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A0A2I1CA30 A0A2I1CA30 A0A2I1CPV7 A0A2I1CPV7 A0A2I1CPK0 A0A2I1CPK0 A0A2I1CMY6 A0A2I1CMY6 A0A2I1CMT8 A0A2I1CMT8 A0A2I1CMR3 A0A2I1CMR3 A0A2I1CMQ0 A0A2I1CMQ0 AAH1 AAH1 A0A2I1CM15 A0A2I1CM15 A0A2I1CLQ7 A0A2I1CLQ7 A0A2I1CLI3 A0A2I1CLI3 A0A2I1CKZ0 A0A2I1CKZ0 A0A2I1CKW5 A0A2I1CKW5 A0A2I1CJQ6 A0A2I1CJQ6 A0A2I1CJB0 A0A2I1CJB0 A0A2I1CJ69 A0A2I1CJ69 A0A2I1CIS0 A0A2I1CIS0 A0A2I1CIF1 A0A2I1CIF1 A0A2I1CIE8 A0A2I1CIE8 A0A2I1CHK1 A0A2I1CHK1 A0A2I1CHI9 A0A2I1CHI9 A0A2I1CHH9 A0A2I1CHH9 A0A2I1CHG3 A0A2I1CHG3 A0A2I1CGS5 A0A2I1CGS5 A0A2I1CGK4 A0A2I1CGK4 A0A2I1CGJ5 A0A2I1CGJ5 A0A2I1CGI8 A0A2I1CGI8 A0A2I1CGA8 A0A2I1CGA8 A0A2I1CGA3 A0A2I1CGA3 A0A2I1CG78 A0A2I1CG78 A0A2I1CG01 A0A2I1CG01 A0A2I1CFZ7 A0A2I1CFZ7 A0A2I1CFP0 A0A2I1CFP0 A0A2I1CFH3 A0A2I1CFH3 A0A2I1CE79 A0A2I1CE79 A0A2I1CDY6 A0A2I1CDY6 A0A2I1CDR4 A0A2I1CDR4 A0A2I1CDM8 A0A2I1CDM8 A0A2I1CCI1 A0A2I1CCI1 A0A2I1CCH1 A0A2I1CCH1 A0A2I1CCD9 A0A2I1CCD9 A0A2I1CC80 A0A2I1CC80 A0A2I1CC43 A0A2I1CC43 A0A2I1CC26 A0A2I1CC26 A0A2I1CBB1 A0A2I1CBB1 A0A2I1CAL0 A0A2I1CAL0 A0A2I1CAD0 A0A2I1CAD0 A0A2I1CA91 A0A2I1CA91 ADK1 ADK1 A0A2I1CA01 A0A2I1CA01 A0A2I1C9M7 A0A2I1C9M7 A0A2I1C940 A0A2I1C940 A0A2I1C8R4 A0A2I1C8R4 A0A2I1C871 A0A2I1C871 A0A2I1C7X3 A0A2I1C7X3 A0A2I1C7W6 A0A2I1C7W6 A0A2I1C755 A0A2I1C755 A0A2I1C738 A0A2I1C738 A0A2I1C6X9 A0A2I1C6X9 A0A2I1C6H3 A0A2I1C6H3 A0A2I1C6E1 A0A2I1C6E1 A0A2I1C6C5 A0A2I1C6C5 A0A2I1C5Y4 A0A2I1C5Y4 A0A2I1C5Q8 A0A2I1C5Q8 A0A2I1C4H5 A0A2I1C4H5 A0A2I1C2L0 A0A2I1C2L0 A0A2I1C1Y1 A0A2I1C1Y1 A0A2I1C1N4 A0A2I1C1N4 A0A2I1C1F0 A0A2I1C1F0 A0A2I1C118 A0A2I1C118 A0A2I1BZV5 A0A2I1BZV5 A0A2I1BZQ5 A0A2I1BZQ5 A0A2I1BZ95 A0A2I1BZ95 A0A2I1BYL3 A0A2I1BYL3 A0A2I1BYH4 A0A2I1BYH4 A0A2I1BY40 A0A2I1BY40 A0A2I1BY00 A0A2I1BY00 A0A2I1BXZ7 A0A2I1BXZ7 A0A2I1BXU2 A0A2I1BXU2 A0A2I1BXM6 A0A2I1BXM6 A0A2I1BXE0 A0A2I1BXE0 ADK2 ADK2 A0A2I1BWC9 A0A2I1BWC9 A0A2I1BVR1 A0A2I1BVR1 A0A2I1BV83 A0A2I1BV83 A0A2I1BUW3 A0A2I1BUW3 A0A2I1BU56 A0A2I1BU56 A0A2I1BTR0 A0A2I1BTR0 A0A2I1BT72 A0A2I1BT72 A0A2I1BSN6 A0A2I1BSN6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A2I1CA30Guanylate kinase. (191 aa)
A0A2I1CPV7Zn(2)-C6 fungal-type domain-containing protein. (655 aa)
A0A2I1CPK0Uncharacterized protein. (178 aa)
A0A2I1CMY6Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
A0A2I1CMT8Orotate phosphoribosyltransferase. (246 aa)
A0A2I1CMR3Putative dihydroorotate reductase pyre. (515 aa)
A0A2I1CMQ0RING-type domain-containing protein. (1033 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (354 aa)
A0A2I1CM15Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (286 aa)
A0A2I1CLQ7Deoxycytidylate deaminase. (379 aa)
A0A2I1CLI3Uridine kinase; Belongs to the uridine kinase family. (453 aa)
A0A2I1CKZ0Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (546 aa)
A0A2I1CKW5Putative C6 transcription factor. (696 aa)
A0A2I1CJQ6Haloacid dehalogenase, type II. (266 aa)
A0A2I1CJB0Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (254 aa)
A0A2I1CJ69Uncharacterized protein. (108 aa)
A0A2I1CIS0Putative ribonucleotide reductase small subunit RnrA. (405 aa)
A0A2I1CIF1Thioredoxin; Belongs to the thioredoxin family. (110 aa)
A0A2I1CIE8Putative nucleoside diphosphatase; Belongs to the GDA1/CD39 NTPase family. (713 aa)
A0A2I1CHK1MutT/nudix family protein; Belongs to the Nudix hydrolase family. (212 aa)
A0A2I1CHI9Putative NUDIX family hydrolase. (302 aa)
A0A2I1CHH9Putative HAD superfamily hydrolase. (244 aa)
A0A2I1CHG3Putative importin 13. (1025 aa)
A0A2I1CGS5Putative adenosine kinase. (351 aa)
A0A2I1CGK4Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (177 aa)
A0A2I1CGJ5Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa)
A0A2I1CGI8Cytosine deaminase-uracil phosphoribosyltransferase fusion protein. (242 aa)
A0A2I1CGA8Nucleoside diphosphate kinase. (153 aa)
A0A2I1CGA3P-loop containing nucleoside triphosphate hydrolase protein. (322 aa)
A0A2I1CG78Thymidylate kinase. (221 aa)
A0A2I1CG01Phosphoribosylformylglycinamidine synthase. (1362 aa)
A0A2I1CFZ7Uncharacterized protein. (367 aa)
A0A2I1CFP0Guanine deaminase. (556 aa)
A0A2I1CFH3Uncharacterized protein. (425 aa)
A0A2I1CE79Amidophosphoribosyltransferase. (583 aa)
A0A2I1CDY6Putative bifunctional purine Ade1. (822 aa)
A0A2I1CDR4Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (320 aa)
A0A2I1CDM8TYR_PHOSPHATASE_2 domain-containing protein. (312 aa)
A0A2I1CCI1Putative guanine deaminase. (454 aa)
A0A2I1CCH1Thioredoxin; Belongs to the thioredoxin family. (125 aa)
A0A2I1CCD9Putative HAD superfamily hydrolase. (292 aa)
A0A2I1CC80Putative bifunctional pyrimidine biosynthesis protein. (2255 aa)
A0A2I1CC43NUDIX domain protein. (222 aa)
A0A2I1CC26Putative formyltetrahydrofolate deformylase. (292 aa)
A0A2I1CBB1Putative 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (667 aa)
A0A2I1CAL0Putative glutaredoxin. (102 aa)
A0A2I1CAD0Uncharacterized protein. (78 aa)
A0A2I1CA91Uncharacterized protein. (447 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (255 aa)
A0A2I1CA01Glutaredoxin domain protein. (245 aa)
A0A2I1C9M7Putative glycerol-3-phosphate phosphatase. (237 aa)
A0A2I1C940Nucleoside diphosphatase Gda1; Belongs to the GDA1/CD39 NTPase family. (503 aa)
A0A2I1C8R4Putative adenosine deaminase. (322 aa)
A0A2I1C871Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (424 aa)
A0A2I1C7X3OMPdecase domain-containing protein. (451 aa)
A0A2I1C7W6Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (554 aa)
A0A2I1C755Putative UDP-sugar hydrolase; Belongs to the 5'-nucleotidase family. (396 aa)
A0A2I1C738Putative nucleotidase. (126 aa)
A0A2I1C6X9Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (529 aa)
A0A2I1C6H3Putative flavo protein. (243 aa)
A0A2I1C6E1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (859 aa)
A0A2I1C6C5Uncharacterized protein. (253 aa)
A0A2I1C5Y4Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (595 aa)
A0A2I1C5Q8Putative acyltransferase. (537 aa)
A0A2I1C4H5Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (555 aa)
A0A2I1C2L0Uncharacterized protein. (409 aa)
A0A2I1C1Y1Phosphoribosyl-aminoimidazole-succinocarboxamide synthase. (302 aa)
A0A2I1C1N4Ser/Thr protein phosphatase family. (541 aa)
A0A2I1C1F0Putative haloacid dehalogenase-like hydrolase. (285 aa)
A0A2I1C118FAD/NAD(P)-binding domain-containing protein. (468 aa)
A0A2I1BZV5Uncharacterized protein. (353 aa)
A0A2I1BZQ5Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (235 aa)
A0A2I1BZ95CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (569 aa)
A0A2I1BYL3Putative phosphoglycolate phosphatase. (231 aa)
A0A2I1BYH4Putative cytidine deaminase. (128 aa)
A0A2I1BY40Adenine phosphoribosyltransferase 1. (217 aa)
A0A2I1BY00Putative AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (937 aa)
A0A2I1BXZ7Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (141 aa)
A0A2I1BXU2Uncharacterized protein. (117 aa)
A0A2I1BXM6Alpha/beta-hydrolase. (367 aa)
A0A2I1BXE0Thioredoxin; Belongs to the thioredoxin family. (108 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (247 aa)
A0A2I1BWC9dUTP diphosphatase. (175 aa)
A0A2I1BVR1Uncharacterized protein. (230 aa)
A0A2I1BV83GMP synthase. (543 aa)
A0A2I1BUW3Tetratricopeptide repeat domain protein. (563 aa)
A0A2I1BU56Alpha/beta-hydrolase. (370 aa)
A0A2I1BTR0Putative cytoplasmic thioredoxin. (109 aa)
A0A2I1BT72Metallo-dependent hydrolase. (435 aa)
A0A2I1BSN6Fungal_trans domain-containing protein. (542 aa)
Your Current Organism:
Aspergillus novofumigatus
NCBI taxonomy Id: 1392255
Other names: A. novofumigatus IBT 16806, Aspergillus novofumigatus IBT 16806
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