(89 nodes) Glyoxylate and dicarboxylate metabolism network (Aspergillus novofumigatus)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	A0A2I1C6W1	Glutamine synthetase bacteria; Belongs to the glutamine synthetase family. (479 aa)
	A0A2I1BTJ6	AB hydrolase-1 domain-containing protein. (246 aa)
	A0A2I1BUV7	Catalase domain-containing protein. (90 aa)
	A0A2I1BV52	Methylaspartate ammonia-lyase C-terminal domain protein. (416 aa)
	A0A2I1BVE5	MACPF domain-containing protein. (583 aa)
	A0A2I1BVK1	Putative MFS transporter. (416 aa)
	A0A2I1BVM5	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (728 aa)
	A0A2I1BWJ7	Wd and tetratricopeptide repeat protein. (1107 aa)
	A0A2I1BX59	Uncharacterized protein. (124 aa)
	A0A2I1BXT1	Putative C6 transcription factor. (761 aa)
	A0A2I1BXU3	Dihydrodipicolinate synthetase family protein; Belongs to the DapA family. (296 aa)
	A0A2I1BXV1	FMN-dependent dehydrogenase family protein. (361 aa)
	A0A2I1BYL3	Putative phosphoglycolate phosphatase. (231 aa)
	A0A2I1BZ42	Malate dehydrogenase. (341 aa)
	A0A2I1BZU4	Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	A0A2I1BZY2	Pyr_redox_2 domain-containing protein. (406 aa)
	A0A2I1C073	Dihydrodipicolinate synthetase family protein; Belongs to the DapA family. (315 aa)
	A0A2I1C0D8	Putative dehydrogenase. (358 aa)
	A0A2I1C118	FAD/NAD(P)-binding domain-containing protein. (468 aa)
	A0A2I1C194	FabD/lysophospholipase-like protein. (957 aa)
	A0A2I1C1Y7	SET domain-containing protein. (421 aa)
	A0A2I1C212	NIPSNAP family protein. (385 aa)
	A0A2I1C2B7	Glutamine synthetase bacteria; Belongs to the glutamine synthetase family. (857 aa)
	A0A2I1C2U0	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (462 aa)
	A0A2I1C3H8	Putative MFS transporter. (529 aa)
	A0A2I1C408	MACPF domain-containing protein. (777 aa)
	A0A2I1C473	Putative MFS multidrug resistance transporter. (556 aa)
	A0A2I1C481	Isocitrate lyase. (538 aa)
	A0A2I1C4D8	Glutamine synthetase. (358 aa)
	A0A2I1C4E9	Putative HAD superfamily hydrolase. (263 aa)
	A0A2I1C4P8	Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
	A0A2I1C4U9	Putative MFS transporter. (574 aa)
	A0A2I1C4W1	SET domain protein. (696 aa)
	A0A2I1C4W9	Acetyl-coenzyme A synthetase. (670 aa)
	A0A2I1C572	Shr3 amino acid permease chaperone. (207 aa)
	A0A2I1C5T5	Dihydrodipicolinate synthetase family protein; Belongs to the DapA family. (324 aa)
	A0A2I1C668	Putative coenzyme A synthetase. (510 aa)
	A0A2I1C6S4	Putative uridine/cytidine kinase. (315 aa)
	A0A2I1C6T0	Putative membrane-spanning ATPase; Belongs to the AAA ATPase family. (419 aa)
	A0A2I1C6T8	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1004 aa)
	A0A2I1C8C9	Putative NAD-dependent D-isomer specific 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
	A0A2I1C8P3	SET domain protein. (494 aa)
	A0A2I1C8P7	Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
	A0A2I1C964	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (175 aa)
	A0A2I1C9F2	Uncharacterized protein. (144 aa)
	A0A2I1C9M6	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (467 aa)
	A0A2I1C9R1	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (295 aa)
	A0A2I1CA08	PLP-dependent transferase. (517 aa)
	A0A2I1CB92	Putative acetyl-CoA-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa)
	A0A2I1CBD4	FabD/lysophospholipase-like protein. (338 aa)
	A0A2I1CBE9	Uncharacterized protein. (720 aa)
	A0A2I1CBP2	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (770 aa)
	A0A2I1CC05	FabD/lysophospholipase-like protein. (376 aa)
	A0A2I1CC26	Putative formyltetrahydrofolate deformylase. (292 aa)
	A0A2I1CC34	Putative alpha/beta hydrolase. (516 aa)
	A0A2I1CDS2	Malate dehydrogenase, NAD-dependent; Belongs to the LDH/MDH superfamily. (330 aa)
	A0A2I1CDU8	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (359 aa)
	A0A2I1CE94	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (746 aa)
	A0A2I1CE98	Citrate synthase; Belongs to the citrate synthase family. (465 aa)
	A0A2I1CE99	Glutamine synthetase; Belongs to the glutamine synthetase family. (502 aa)
	A0A2I1CEA0	Malate synthase; Belongs to the malate synthase family. (539 aa)
	A0A2I1CEC9	MFS general substrate transporter. (292 aa)
	A0A2I1CEM3	Isocitrate lyase. (602 aa)
	A0A2I1CFJ8	SET domain protein. (428 aa)
	A0A2I1CFQ3	Putative MFS transporter. (585 aa)
	A0A2I1CGF3	Citrate synthase; Belongs to the citrate synthase family. (429 aa)
	A0A2I1CGH3	Uncharacterized protein. (58 aa)
	A0A2I1CH45	Putative MFS transporter. (428 aa)
	A0A2I1CH97	2OG-FeII_Oxy_2 domain-containing protein. (508 aa)
	A0A2I1CHA1	Carboxyphosphonoenolpyruvate phosphonomutase-like protein. (271 aa)
	A0A2I1CHB2	Uncharacterized protein. (136 aa)
	A0A2I1CHD7	Propionyl-CoA carboxylase. (531 aa)
	A0A2I1CJ23	Putative C6 transcription factor. (1043 aa)
	A0A2I1CJS7	Citrate synthase; Belongs to the citrate synthase family. (474 aa)
	A0A2I1CJU4	Catalase. (582 aa)
	A0A2I1CK68	Dihydrodipicolinate synthetase family protein. (331 aa)
	A0A2I1CK70	Putative D-mandelate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
	A0A2I1CKF7	Formamidase FmdS. (351 aa)
	A0A2I1CKI5	Dihydrolipoyl dehydrogenase. (513 aa)
	A0A2I1CL60	Putative C6 transcription factor. (807 aa)
	A0A2I1CLG8	Putative MFS transporter. (437 aa)
	A0A2I1CLU7	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (537 aa)
	A0A2I1CLX3	Putative patatin-like serine hydrolase. (590 aa)
	A0A2I1CNA4	Putative mitochondrial AAA ATPase. (952 aa)
	A0A2I1CNQ8	Aldolase; Belongs to the DapA family. (282 aa)
	A0A2I1CNU3	Putative oxalate decarboxylase. (449 aa)
	A0A2I1CP03	Citrate synthase; Belongs to the citrate synthase family. (440 aa)
	A0A2I1CP09	Putative MFS efflux transporter. (498 aa)
	A0A2I1CP31	Glutamine synthetase/guanido kinase; Belongs to the glutamine synthetase family. (288 aa)

Your Current Organism:

Aspergillus novofumigatus

NCBI taxonomy Id: 1392255
Other names: A. novofumigatus IBT 16806, Aspergillus novofumigatus IBT 16806

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A2I1BTJ6	A0A2I1BUV7	AB hydrolase-1 domain-containing protein.	Catalase domain-containing protein.	0.728
A0A2I1BTJ6	A0A2I1BVM5	AB hydrolase-1 domain-containing protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.	0.835
A0A2I1BTJ6	A0A2I1BXU3	AB hydrolase-1 domain-containing protein.	Dihydrodipicolinate synthetase family protein; Belongs to the DapA family.	0.720
A0A2I1BTJ6	A0A2I1BYL3	AB hydrolase-1 domain-containing protein.	Putative phosphoglycolate phosphatase.	0.824
A0A2I1BTJ6	A0A2I1C073	AB hydrolase-1 domain-containing protein.	Dihydrodipicolinate synthetase family protein; Belongs to the DapA family.	0.720
A0A2I1BTJ6	A0A2I1C0D8	AB hydrolase-1 domain-containing protein.	Putative dehydrogenase.	0.535
A0A2I1BTJ6	A0A2I1C481	AB hydrolase-1 domain-containing protein.	Isocitrate lyase.	0.852
A0A2I1BTJ6	A0A2I1C4E9	AB hydrolase-1 domain-containing protein.	Putative HAD superfamily hydrolase.	0.528
A0A2I1BTJ6	A0A2I1C4P8	AB hydrolase-1 domain-containing protein.	Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.840
A0A2I1BTJ6	A0A2I1C5T5	AB hydrolase-1 domain-containing protein.	Dihydrodipicolinate synthetase family protein; Belongs to the DapA family.	0.830
A0A2I1BTJ6	A0A2I1C8C9	AB hydrolase-1 domain-containing protein.	Putative NAD-dependent D-isomer specific 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.840
A0A2I1BTJ6	A0A2I1C8P7	AB hydrolase-1 domain-containing protein.	Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.840
A0A2I1BTJ6	A0A2I1CA08	AB hydrolase-1 domain-containing protein.	PLP-dependent transferase.	0.908
A0A2I1BTJ6	A0A2I1CE94	AB hydrolase-1 domain-containing protein.	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.	0.835
A0A2I1BTJ6	A0A2I1CEA0	AB hydrolase-1 domain-containing protein.	Malate synthase; Belongs to the malate synthase family.	0.893
A0A2I1BTJ6	A0A2I1CEM3	AB hydrolase-1 domain-containing protein.	Isocitrate lyase.	0.852
A0A2I1BTJ6	A0A2I1CH97	AB hydrolase-1 domain-containing protein.	2OG-FeII_Oxy_2 domain-containing protein.	0.539
A0A2I1BTJ6	A0A2I1CHA1	AB hydrolase-1 domain-containing protein.	Carboxyphosphonoenolpyruvate phosphonomutase-like protein.	0.425
A0A2I1BTJ6	A0A2I1CHB2	AB hydrolase-1 domain-containing protein.	Uncharacterized protein.	0.539
A0A2I1BTJ6	A0A2I1CJ23	AB hydrolase-1 domain-containing protein.	Putative C6 transcription factor.	0.425