(40 nodes) Ribosome assembly network (Anopheles culicifacies)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182LV67	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (152 aa)
	A0A182M980	WD_REPEATS_REGION domain-containing protein. (991 aa)
	A0A182M8E0	WD_REPEATS_REGION domain-containing protein. (477 aa)
	A0A182M864	60S ribosomal protein L5. (297 aa)
	A0A182M6Y2	Uncharacterized protein. (301 aa)
	A0A182M6H1	40S ribosomal protein S27. (84 aa)
	A0A182M6G6	EFG_C domain-containing protein. (160 aa)
	A0A182M5T0	G domain-containing protein. (391 aa)
	A0A182M4M0	40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (149 aa)
	A0A182LZE9	VWFA domain-containing protein. (6137 aa)
	A0A182LZB4	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (315 aa)
	A0A182LVP4	RRM domain-containing protein. (256 aa)
	A0A182LVC9	Uncharacterized protein. (514 aa)
	A0A182LTN0	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (382 aa)
	A0A182LSX6	Ribosomal_L16 domain-containing protein. (219 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (243 aa)
	A0A182LS23	FtsJ domain-containing protein. (242 aa)
	A0A2C9GUJ9	39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. (131 aa)
	A0A182MX78	Uncharacterized protein. (158 aa)
	A0A182MWT4	Ku domain-containing protein. (728 aa)
	A0A182MUP0	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (410 aa)
	A0A182MTG4	40S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (233 aa)
	A0A182MSU5	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (198 aa)
	A0A182MR80	Brix domain-containing protein. (493 aa)
	A0A182MR76	Uncharacterized protein. (253 aa)
	A0A182MQI4	Uncharacterized protein. (345 aa)
	A0A182MQG0	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (1736 aa)
	A0A182MQ38	Uncharacterized protein. (141 aa)
	A0A182MNM5	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (282 aa)
	A0A182MMT8	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (173 aa)
	A0A182MMJ7	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4153 aa)
	A0A182MM93	Ribosomal_S7 domain-containing protein. (433 aa)
	A0A182MLC6	Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (198 aa)
	A0A182MKC3	Ribosomal_L16 domain-containing protein. (219 aa)
	A0A182MK37	Brix domain-containing protein. (330 aa)
	A0A182MFI4	Uncharacterized protein. (199 aa)
	A0A182MEH4	Brix domain-containing protein. (414 aa)
	A0A182MDF8	Uncharacterized protein. (267 aa)
	A0A182MBM9	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (286 aa)
	A0A182MAW8	60S ribosomal protein L6. (266 aa)

Your Current Organism:

Anopheles culicifacies

NCBI taxonomy Id: 139723
Other names: A. culicifacies

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182LS23	A0A182LSX6	A0A182LS23	A0A182LSX6	FtsJ domain-containing protein.	Ribosomal_L16 domain-containing protein.	0.410
A0A182LS23	A0A182LTN0	A0A182LS23	A0A182LTN0	FtsJ domain-containing protein.	Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.	0.831
A0A182LS23	A0A182LV67	A0A182LS23	A0A182LV67	FtsJ domain-containing protein.	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.576
A0A182LS23	A0A182LVC9	A0A182LS23	A0A182LVC9	FtsJ domain-containing protein.	Uncharacterized protein.	0.685
A0A182LS23	A0A182LVP4	A0A182LS23	A0A182LVP4	FtsJ domain-containing protein.	RRM domain-containing protein.	0.599
A0A182LS23	A0A182LZB4	A0A182LS23	A0A182LZB4	FtsJ domain-containing protein.	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.	0.766
A0A182LS23	A0A182M6Y2	A0A182LS23	A0A182M6Y2	FtsJ domain-containing protein.	Uncharacterized protein.	0.638
A0A182LS23	A0A182M980	A0A182LS23	A0A182M980	FtsJ domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.741
A0A182LS23	A0A182MAW8	A0A182LS23	A0A182MAW8	FtsJ domain-containing protein.	60S ribosomal protein L6.	0.643
A0A182LS23	A0A182MEH4	A0A182LS23	A0A182MEH4	FtsJ domain-containing protein.	Brix domain-containing protein.	0.864
A0A182LS23	A0A182MFI4	A0A182LS23	A0A182MFI4	FtsJ domain-containing protein.	Uncharacterized protein.	0.576
A0A182LS23	A0A182MK37	A0A182LS23	A0A182MK37	FtsJ domain-containing protein.	Brix domain-containing protein.	0.806
A0A182LS23	A0A182MKC3	A0A182LS23	A0A182MKC3	FtsJ domain-containing protein.	Ribosomal_L16 domain-containing protein.	0.410
A0A182LS23	A0A182MMT8	A0A182LS23	A0A182MMT8	FtsJ domain-containing protein.	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.879
A0A182LS23	A0A182MNM5	A0A182LS23	A0A182MNM5	FtsJ domain-containing protein.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.766
A0A182LS23	A0A182MR80	A0A182LS23	A0A182MR80	FtsJ domain-containing protein.	Brix domain-containing protein.	0.420
A0A182LS23	A0A182MUP0	A0A182LS23	A0A182MUP0	FtsJ domain-containing protein.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.892
A0A182LS23	A0A2C9GUJ9	A0A182LS23	A0A2C9GUJ9	FtsJ domain-containing protein.	39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family.	0.678
A0A182LS23	EIF6	A0A182LS23	A0A182LSF6	FtsJ domain-containing protein.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.854
A0A182LSX6	A0A182LS23	A0A182LSX6	A0A182LS23	Ribosomal_L16 domain-containing protein.	FtsJ domain-containing protein.	0.410