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| | phoB | Phosphate regulon transcriptional regulator PhoR protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is re [...] (372 aa) |
| | phoU | Phosphate uptake regulator PhoU protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (497 aa) |
| | pstS | ABC phosphate transporter periplasmic phosphate-binding protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (302 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase SDAP desuccinylase protein. (60 aa) |
| | truA | tRNA pseudouridine synthase A protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (718 aa) |
| | def1 | Peptide deformylase 1 PDF 1 protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (323 aa) |
| | rbfA-2 | RmuC domain containing protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (178 aa) |
| | nusA-2 | NAD+ diphosphatase protein; Participates in both transcription termination and antitermination. (572 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (212 aa) |
| | ybeY | ABC transporter nucleotide binding-ATPase protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (190 aa) |
| | miaB-2 | Leucyl aminopeptidase protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (441 aa) |
| | ERL46680.1 | Membrane lipoprotein. (246 aa) |
| | pheS | Phenylalanine--tRNA ligase alpha subunit protein; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (339 aa) |
| | yhdW | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (918 aa) |
| | queG | Epoxyqueuosine reductase protein; Belongs to the UPF0102 family. (127 aa) |
| | rsmI-2 | Glutathione S-transferase protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (295 aa) |
| | rph-2 | Ribonuclease D protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (243 aa) |
| | ERL46660.1 | OstA-like protein. (181 aa) |
| | dnaJ-2 | SSU ribosomal protein S30P; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between Dna [...] (370 aa) |
| | ERL46655.1 | Hypothetical protein. (179 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta ACCase subunit beta Acetyl-C protein. (214 aa) |
| | dnaQ-2 | ATP-dependent DNA helicase PcrA protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (232 aa) |
| | hprK | HPr kinase-phosphorylase protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (421 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase ATP PEP carboxykinase protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (446 aa) |
| | polA | DNA polymerase I protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (631 aa) |
| | rsmG-2 | ABC transporter ATP-binding protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (226 aa) |
| | bfrE | Putative TonB-dependent receptor for iron transport protein. (358 aa) |
| | leuS-2 | Polyketide biosynthesis O-methyltransferase protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (862 aa) |
| | gyrB | DNA gyrase subunit B protein. (266 aa) |
| | ftsK | DNA translocase FtsK protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (459 aa) |
| | atuA | Expressed protein with apparent function in citronellol catabolism; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (357 aa) |
| | rlmN | enoyl-CoA hydratase protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (381 aa) |
| | ERL46485.1 | Alcohol dehydrogenase protein; Belongs to the sigma-70 factor family. ECF subfamily. (223 aa) |
| | ERL46484.1 | Hypothetical protein. (169 aa) |
| | ERL46468.1 | Isoquinoline 1-oxidoreductase protein. (427 aa) |
| | rimM-2 | acyl-CoA dehydrogenase protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (197 aa) |
| | trmD-2 | Pyruvate dehydrogenase E1 component subunit alpha protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (232 aa) |
| | ERL46452.1 | 3alphaor 20beta-hydroxysteroid dehydrogenase protein. (372 aa) |
| | ERL46445.1 | Putative CHAIN-FATTY-ACID-CoA LIGASE FADD13 FATTY-ACYL-CoA SYNTHETASE protein; Belongs to the 'phage' integrase family. (309 aa) |
| | priA-2 | Domain containing protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (731 aa) |
| | rlmH-2 | 3or 17beta-hydroxysteroid dehydrogenase protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (158 aa) |
| | ERL46418.1 | Protein-tyrosine phosphatase-like protein; Belongs to the SUA5 family. (227 aa) |
| | ileS-2 | Phosphoadenosine phosphosulfate reductase protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (937 aa) |
| | hisS-2 | Cytochro ccmD. (491 aa) |
| | rpsP | 30S ribosomal protein S16; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (627 aa) |
| | trmD | tRNA -methyltransferase protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (164 aa) |
| | rplS | 50S ribosomal protein L19; Belongs to the pseudouridine synthase RsuA family. (330 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit protein. (184 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase ASA dehydrogenase protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (492 aa) |
| | sucB | 2-oxoglutarate dehydrogenase E2 component protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (255 aa) |
| | nadD | Putative nicotinate-nucleotide adenylyltransferase protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (141 aa) |
| | ERL46323.1 | MIP family protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (173 aa) |
| | arsC | ArsC protein; Belongs to the N(4)/N(6)-methyltransferase family. (376 aa) |
| | ERL46320.1 | Hypothetical protein; Adenine glycosylase active on G-A mispairs. (357 aa) |
| | smc-2 | N-methylhydantoinase B protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1174 aa) |
| | glyQ-2 | Hypothetical protein. (291 aa) |
| | glyS-2 | Peptidase M23 protein. (693 aa) |
| | pilD | Type 4 prepilin-like protein leader peptide-processing enzyme. (191 aa) |
| | ERL46290.1 | Methylation site domain containing protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (320 aa) |
| | xseB-2 | Adenylate cyclase protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (85 aa) |
| | ERL46284.1 | Peptidase M16 domain-containing protein; Overlaps CDS with the same product name. (259 aa) |
| | hisG | ATP phosphoribosyltransferase protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (179 aa) |
| | hisZ | HisZ protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (220 aa) |
| | hisS | Histidine--tRNA ligase protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (355 aa) |
| | tilS-2 | butyryl-CoA dehydrogenase protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (439 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (321 aa) |
| | ERL46253.1 | 3-deoxy-D-manno-octulosonic-acid transferase protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (337 aa) |
| | coxII | Cytochrome c oxidase subunit 2; Belongs to the sigma-70 factor family. (238 aa) |
| | ERL46188.1 | Beta-lactamase protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (493 aa) |
| | dxs2 | 1-deoxy-D-xylulose-5-phosphate synthase 2 protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (396 aa) |
| | tolR | TolR protein. (351 aa) |
| | ftsH | ATP-dependent zinc metalloprotease FtsH protein. (287 aa) |
| | miaA | Hypothetical protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (334 aa) |
| | fliG | Putative flagellar motor switch protein FliG; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (436 aa) |
| | fliR | Flagellar biosynthetic protein fliR; Belongs to the BolA/IbaG family. (84 aa) |
| | cysS-2 | ThiJ-PfpI family protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (449 aa) |
| | thrS-2 | Putative ELECTRON TRANSFER PROTEIN FDXB; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (653 aa) |
| | ERL46064.1 | Nicotinate-nucleotide adenylyltransferase protein; Belongs to the UPF0176 family. (331 aa) |
| | ERL46040.1 | acyl-CoA dehydrogenase protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (266 aa) |
| | ERL47028.1 | Hypothetical protein; Belongs to the 'phage' integrase family. (326 aa) |
| | cas9 | NAD-dependent epimerase-dehydratase protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and [...] (1110 aa) |
| | ERL47011.1 | Glycerate kinase protein. (222 aa) |
| | rpoZ-2 | Outer membrane receptor for transport of vitamin B putative protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (148 aa) |
| | rnc | Trans-aconitate 2-methyltransferase protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (232 aa) |
| | recO-2 | Hypothetical protein; Involved in DNA repair and RecF pathway recombination. (242 aa) |
| | tuf | Elongation factor Tu protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (750 aa) |
| | nusB | Hypothetical protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (155 aa) |
| | pdhAa | Pyruvate dehydrogenase E1 component alpha subunit protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (104 aa) |
| | ERL46966.1 | Hypothetical protein; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa) |
| | ivdH | Isovaleryl-CoA dehydrogenase protein. (258 aa) |
| | ERL46932.1 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 protein. (348 aa) |
| | ERL46929.1 | 5-amino-6-uracil reductase protein; Belongs to the 'phage' integrase family. (322 aa) |
| | dusA | Pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (327 aa) |
| | rsmH-2 | Hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (348 aa) |
| | ERL47713.1 | Beta-lactamase protein; May be involved in recombinational repair of damaged DNA. (555 aa) |
| | ptrB | Protease II protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (706 aa) |
| | ERL47702.1 | ABC transporter permease protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (519 aa) |
| | ERL47700.1 | NMT1-THI5-like domain-containing protein. (430 aa) |
| | cycH | Cytochrome c-type biosis protein CycH; Belongs to the peptidase S24 family. (140 aa) |
| | ftsQ | Cell division protein FtsQ; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (363 aa) |
| | ftsA | Cell division protein ftsA; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (887 aa) |
| | ftsZ1 | Cell division protein FtsZ; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (265 aa) |
| | uvrC-2 | RNA polymerase sigma-54 factor protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (623 aa) |
| | umuD | UmuD protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-D [...] (757 aa) |
| | dnaG-2 | Catechol O-methyltransferase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (622 aa) |
| | rpoD-2 | Prenyltransferase-like domain containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (651 aa) |
| | alaS | Alanine--tRNA ligase protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (452 aa) |
| | rlmE-2 | Domain containing protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (228 aa) |
| | dnaG | DNA primase protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (464 aa) |
| | ERL47584.1 | Dihydroorotate oxidase protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (509 aa) |
| | dhs | 2-dehydro-3-deoxyphosphoheptonate aldolase protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (283 aa) |
| | ERL47567.1 | Putative Multidrug resistance protein. (152 aa) |
| | guaA | GMP synthase glutamine-hydrolyzing protein; Belongs to the DnaA family. (237 aa) |
| | ERL47558.1 | Integral membrane protein. (88 aa) |
| | sppA | Protease 4 protein. (306 aa) |
| | aspS | Hypothetical protein; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (591 aa) |
| | purF | Amidophosphoribosyltransferase protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (836 aa) |
| | rpsR | 30S ribosomal protein S18; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (417 aa) |
| | rnd | Ribonuclease D RNase D protein; Overlaps another CDS with the same product name. (594 aa) |
| | valS-2 | Hypothetical protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (887 aa) |
| | ERL47476.1 | Hypothetical protein. (261 aa) |
| | argS | Gamma-glutamyl-gamma-aminobutyrate hydrolase protein. (583 aa) |
| | serS-2 | Hypothetical protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | trmFO-2 | Hypothetical protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (471 aa) |
| | uvrA-2 | Hypothetical protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (982 aa) |
| | ERL47455.1 | precorrin-8W decarboxylase protein. (155 aa) |
| | gyrA-2 | Putative Outer membrane protein TolC; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependen [...] (966 aa) |
| | tgt-2 | 1-deoxy-D-xylulose-5-phosphate reductoisomerase protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' [...] (378 aa) |
| | coaD | Phosphopantetheine adenylyltransferase protein; Belongs to the 'phage' integrase family. (411 aa) |
| | mfd-2 | Protein 3-oxoalanine-rating enzyme family protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1170 aa) |
| | ERL47424.1 | TonB system biopolymer transport component protein. (273 aa) |
| | metG-2 | alpha-methylacyl-CoA racemase protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (511 aa) |
| | ERL47357.1 | Haloacetate dehalogenase protein. (369 aa) |
| | ntrY | Nitrogen regulation protein NtrY Signal transduction histidine kinase. (238 aa) |
| | prnA | Tryptophan halogenase protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (356 aa) |
| | ispF | 2-C-methyl-D-erythritol 24-cyclodiphosphate synthase protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (222 aa) |
| | gltX | Cyclase-dehydrase protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (464 aa) |
| | trpC | Indole-3-glycerol phosphate synthase protein. (1164 aa) |
| | proS | Hypothetical protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (445 aa) |
| | lpxB | Lipid-A-disaccharide synthase protein. (558 aa) |
| | clpX | ATP-dependent Clp protease ATP-binding subunit ClpX protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (702 aa) |
| | clpP | ATP-dependent Clp protease proteolytic subunit protein; Belongs to the DEAD box helicase family. (460 aa) |
| | ERL47244.1 | NADH dehydrogenase protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (154 aa) |
| | ERL47240.1 | enoyl-CoA hydratase protein. (121 aa) |
| | gatA | Glutamyl-tRNA amidotransferase subunit A Glu-ADT subunit A protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage aro [...] (843 aa) |
| | gatC | Aspartyl-glutamyl-tRNA amidotransferase subunit C Asp-Glu-ADT subunit C protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (785 aa) |
| | dinB-2 | Nuclease protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (442 aa) |
| | pccA | Propionyl-CoA carboxylase alpha subunit protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (332 aa) |
| | rpoA-2 | ATP12 ATPase protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (339 aa) |
| | rpoC-2 | Elongation factor Tu protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1388 aa) |
| | fusA | Elongation factor G protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1363 aa) |
| | rplL | 50S ribosomal protein L7-L12; Participates in transcription elongation, termination and antitermination. (176 aa) |
| | recF-2 | Agmatinase protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (398 aa) |
| | nspC | Carboxynorspermidine-carboxyspermidine decarboxylase protein. (248 aa) |
| | ERL46724.1 | Saccharopine dehydrogenase NAD+ L-lysine forming protein. (564 aa) |
| | ERL46730.1 | Iron ABC transporter periplasmic binding protein. (123 aa) |
| | argF | Ornithine carbamoyltransferase protein. (514 aa) |
| | polA-2 | Membrane lipoprotein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (950 aa) |
| | ERL46746.1 | Glutathione S-transferase protein. (506 aa) |
| | ERL46748.1 | NADH dehydrogenase protein. (1024 aa) |
| | ihfB-2 | Glutathione S-transferase protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (95 aa) |
| | ERL46769.1 | Ral secretion pathway protein D. (204 aa) |
| | queG-2 | Type II secretion system protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (400 aa) |
| | pheS-2 | Hydroxyacylglutathione hydrolase protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (368 aa) |
| | pheT-2 | Sulfate transporter protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (804 aa) |
| | dnaX-2 | Phosphoribosylanthranilate isomerase protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (649 aa) |
| | recR-2 | Hypothetical protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa) |
| | ERL46801.1 | Hypothetical protein. (373 aa) |
| | fmt-2 | Hypothetical protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (309 aa) |
| | truA-2 | Hypothetical protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (248 aa) |
| | ptsI | Phosphoenolpyruvate-protein phosphotransferase PtsI; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (121 aa) |
| | yffB | Protein YffB. (130 aa) |
| | lysS-2 | Hypothetical protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (531 aa) |
| | etfA | Electron transfer flavoprotein alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (656 aa) |
| | hbdA | 3-hydroxyacyl-CoA dehydrogenase protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (319 aa) |
| | ERL46869.1 | Trans-aconitate 2-methyltransferase protein. (410 aa) |
| | ERL45935.1 | Hypothetical protein. (143 aa) |
| | xerC-2 | Hypothetical protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (323 aa) |
| | ERL45946.1 | Hypothetical protein; Belongs to the BolA/IbaG family. (93 aa) |
| | ERL45947.1 | Hypothetical protein. (193 aa) |
| | ERL45956.1 | Hypothetical protein; Belongs to the sigma-70 factor family. (299 aa) |
| | ERL45964.1 | Hypothetical protein; Belongs to the sulfur carrier protein TusA family. (75 aa) |
| | ERL45972.1 | Hypothetical protein. (201 aa) |
| | ERL45973.1 | Hypothetical protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (295 aa) |
| | ERL46006.1 | Hypothetical protein; Belongs to the 'phage' integrase family. (324 aa) |
| | ERL46025.1 | Hypothetical protein. (599 aa) |
