STRINGSTRING
AB434_0688 AB434_0688 AB434_4045 AB434_4045 AB434_4016 AB434_4016 AB434_4014 AB434_4014 AB434_4013 AB434_4013 AB434_3966 AB434_3966 AB434_3798 AB434_3798 AB434_3795 AB434_3795 polA polA rnhC rnhC mutS2 mutS2 uvrC uvrC AB434_3642 AB434_3642 AB434_3617 AB434_3617 AB434_3581 AB434_3581 ybeY ybeY nfo nfo xseA xseA xseB xseB rnz rnz dinG dinG recU recU AB434_3229 AB434_3229 AB434_3189 AB434_3189 rnmV rnmV AB434_1168 AB434_1168 AB434_1160 AB434_1160 AB434_1146 AB434_1146 rnpA rnpA AB434_1106 AB434_1106 AB434_1077 AB434_1077 AB434_0873 AB434_0873 AB434_0821 AB434_0821 uvrA uvrA AB434_2224 AB434_2224 AB434_2246 AB434_2246 yhaM yhaM addB addB addA addA AB434_2422 AB434_2422 AB434_2423 AB434_2423 rnj rnj AB434_2677 AB434_2677 rnc rnc rnhB rnhB polC polC rnj-2 rnj-2 rny rny AB434_2853 AB434_2853 AB434_2862 AB434_2862 AB434_2891 AB434_2891 AB434_3099 AB434_3099 AB434_3142 AB434_3142 AB434_1869 AB434_1869 AB434_2024 AB434_2024 uvrB uvrB AB434_1244 AB434_1244 mrnC mrnC AB434_1336 AB434_1336 AB434_1344 AB434_1344 AB434_1834 AB434_1834 AB434_1467 AB434_1467 AB434_1483 AB434_1483 AB434_1686 AB434_1686 AB434_1729 AB434_1729 AB434_1777 AB434_1777 AB434_1822 AB434_1822 AB434_0055 AB434_0055 rnr rnr AB434_0083 AB434_0083 AB434_0149 AB434_0149 AB434_0248 AB434_0248 AB434_0249 AB434_0249 AB434_0361 AB434_0361 cas2 cas2 cas1 cas1 AB434_0400 AB434_0400 AB434_0403 AB434_0403 AB434_0507 AB434_0507 AB434_0508 AB434_0508 AB434_0512 AB434_0512 AB434_0514 AB434_0514 AB434_0575 AB434_0575 AB434_0578 AB434_0578 AB434_0627 AB434_0627 AB434_0687 AB434_0687
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AB434_0688Hypothetical protein. (90 aa)
AB434_4045Hypothetical protein. (146 aa)
AB434_4016Hypothetical protein. (236 aa)
AB434_4014Hypothetical protein. (63 aa)
AB434_4013Mobile element protein. (83 aa)
AB434_3966Phage-encoded chromosome degrading nuclease YokF. (262 aa)
AB434_37983'-to-5' oligoribonuclease A. (312 aa)
AB434_3795DNA polymerase III alpha subunit. (1114 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (888 aa)
rnhCRibonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (311 aa)
mutS2Recombination inhibitory protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (784 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (590 aa)
AB434_3642Cytoplasmic axial filament protein CafA and Ribonuclease G. (497 aa)
AB434_3617Single-stranded-DNA-specific exonuclease RecJ. (787 aa)
AB434_3581Putative Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (138 aa)
ybeYMetal-dependent hydrolase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (156 aa)
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (299 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (451 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (75 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (305 aa)
dinGDinG family ATP-dependent helicase YoaA; 3'-5' exonuclease. (930 aa)
recURecU Holliday junction resolvase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (201 aa)
AB434_3229DNA polymerase III polC-type. (320 aa)
AB434_3189Hypothetical protein. (55 aa)
rnmVRibonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (200 aa)
AB434_1168Putative deoxyribonuclease YcfH. (276 aa)
AB434_1160DNA polymerase III delta prime subunit. (337 aa)
AB434_1146DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (381 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (114 aa)
AB434_1106Zn-dependent hydrolase (beta-lactamase superfamily). (264 aa)
AB434_1077Type I restriction-modification system, restriction subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1082 aa)
AB434_0873Programmed cell death toxin YdcE. (101 aa)
AB434_0821Hypothetical protein. (314 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (954 aa)
AB434_2224Hypothetical protein. (308 aa)
AB434_2246DNA repair exonuclease family protein YhaO. (423 aa)
yhaM3'->5' exoribonuclease YhaM; Shows a 3'-5' exoribonuclease activity. (314 aa)
addBATP-dependent nuclease, subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1167 aa)
addAATP-dependent nuclease, subunit A; ATP-dependent DNA helicase. (1243 aa)
AB434_2422Type III restriction-modification system StyLTI enzyme res. (986 aa)
AB434_2423Putative ATP-dependent endonuclease, OLD family. (539 aa)
rnjRibonuclease J1 (endonuclease and 5' exonuclease); An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. (555 aa)
AB434_2677Protein YicC. (287 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (246 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (255 aa)
polCDNA polymerase III alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1442 aa)
rnj-2Ribonuclease J2; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily. (556 aa)
rnyHydrolase (HAD superfamily); Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (520 aa)
AB434_2853DNA polymerase I. (299 aa)
AB434_2862HD domain protein. (237 aa)
AB434_2891ATP-dependent DNA ligase. (621 aa)
AB434_3099Exodeoxyribonuclease III. (251 aa)
AB434_31423'-to-5' oligoribonuclease B. (395 aa)
AB434_1869Hypothetical protein. (71 aa)
AB434_2024DNA repair exonuclease family protein YhaO. (424 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (666 aa)
AB434_1244Membrane-associated protein. (361 aa)
mrnCRibonuclease III family protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (137 aa)
AB434_1336Phage-encoded chromosome degrading nuclease YokF. (413 aa)
AB434_1344Hypothetical protein. (315 aa)
AB434_1834Hypothetical protein. (179 aa)
AB434_1467Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (361 aa)
AB434_1483Hypothetical protein. (309 aa)
AB434_1686Putative ATP-dependent endonuclease, OLD family. (623 aa)
AB434_1729Hypothetical protein. (383 aa)
AB434_1777Hypothetical protein. (318 aa)
AB434_1822Hypothetical protein. (313 aa)
AB434_0055Hypothetical protein. (305 aa)
rnr3'-to-5' exoribonuclease RNase R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (762 aa)
AB434_0083Hypothetical protein. (304 aa)
AB434_0149Hypothetical protein. (345 aa)
AB434_0248Hypothetical protein. (45 aa)
AB434_0249Hypothetical protein. (90 aa)
AB434_0361Ribonuclease BN; Belongs to the UPF0761 family. (307 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (96 aa)
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (343 aa)
AB434_0400CRISPR-associated RecB family exonuclease Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (218 aa)
AB434_0403CRISPR-associated protein, Cas5d family. (239 aa)
AB434_0507ATPase. (804 aa)
AB434_0508Type I restriction-modification system, restriction subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1027 aa)
AB434_0512Hypothetical protein. (136 aa)
AB434_0514Hypothetical protein. (78 aa)
AB434_0575Hypothetical protein. (297 aa)
AB434_0578Hypothetical protein. (329 aa)
AB434_06275-methylcytosine-specific restriction related enzyme. (675 aa)
AB434_0687Hypothetical protein. (45 aa)
Your Current Organism:
Bacillus coagulans
NCBI taxonomy Id: 1398
Other names: ATCC 7050, B. coagulans, BCRC 10606, Bacillus sp. NCIM 2323, CCM 2013, CCRC 10606, CCRC:10606, CCUG 7417, CFBP 4225, CIP 66.25, DSM 1, IFO 12583, IMET 10993, JCM 2257, LMG 6326, LMG:6326, Lactobacillus sp. T4, NBRC 12583, NCAIM B.01086, NCCB 48014, NCCB 77025, NCIB 9365, NCIMB 9365, NCTC 10334, NRRL NRS-609, VKM B-731
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