66 items (Sparassis crispa) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	SCP_0302530	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (157 aa)
	SCP_0302760	Uncharacterized protein. (254 aa)
	SCP_0305810	Uncharacterized protein. (233 aa)
	SCP_0313440	Uncharacterized protein. (403 aa)
	SCP_0403220	Mitochondrial protein. (332 aa)
	BNA5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (465 aa)
	BNA4	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (509 aa)
	SCP_0405640	NAD/NADP-dependent indole-3-acetaldehyde reductase. (280 aa)
	SCP_0103800	Probable hexaprenyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (467 aa)
	SCP_0105050	Uncharacterized protein. (370 aa)
	SCP_0112960	Hydrolase. (396 aa)
	SCP_0206220	Glutathione-independent glyoxalase HSP31. (224 aa)
	SCP_0208900	3-ketodihydrosphingosine reductase TSC10. (347 aa)
	SCP_0605390	G domain-containing protein. (325 aa)
	SCP_0405630	NAD/NADP-dependent indole-3-acetaldehyde reductase. (300 aa)
	SCP_0407470	Probable hydroxyacylglutathione hydrolase. (253 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (230 aa)
	SCP_0412030	Uncharacterized methyltransferase. (244 aa)
	SCP_0412380	Short-chain dehydrogenase/reductase tropE; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa)
	SCP_0413150	Short-chain dehydrogenase/reductase tropE; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
	SCP_0502430	NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial. (365 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (305 aa)
	SCP_0507420	Adrenodoxin homolog, mitochondrial. (152 aa)
	SCP_0508910	Uncharacterized protein. (447 aa)
	SCP_0412420	Short-chain dehydrogenase/reductase tropE; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (242 aa)
	SCP_1600410	Uncharacterized protein. (432 aa)
	SCP_1600330	Uncharacterized protein. (492 aa)
	SCP_1402390	Uncharacterized protein. (464 aa)
	SCP_1301070	Uncharacterized protein. (369 aa)
	SCP_1203790	Uncharacterized protein. (745 aa)
	SCP_1203750	Uncharacterized protein. (431 aa)
	SCP_1203340	Uncharacterized protein. (393 aa)
	SCP_1202800	Indoleamine 2,3-dioxygenase. (445 aa)
	SCP_1202140	Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. (208 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (292 aa)
	SCP_0509510	Uncharacterized protein. (393 aa)
	SCP_1104260	F-box domain-containing protein. (455 aa)
	SCP_1104350	Uncharacterized protein. (429 aa)
	SCP_1103960	F-box domain-containing protein. (526 aa)
	SCP_1800130	Uncharacterized protein. (443 aa)
	SCP_1700240	Reductase. (167 aa)
	SCP_1700220	NADPH-dependent conjugated polyketone reductase C1. (271 aa)
	SCP_0209510	Uncharacterized aminotransferase. (440 aa)
	SCP_0210300	Uncharacterized protein. (443 aa)
	SCP_0210470	Polyketide_cyc domain-containing protein. (230 aa)
	SCP_0211350	Uncharacterized protein. (416 aa)
	SCP_1603030	Uncharacterized protein. (293 aa)
	SCP_1601470	F-box domain-containing protein. (448 aa)
	SCP_1600930	F-box domain-containing protein. (406 aa)
	SCP_1104090	Uncharacterized protein. (572 aa)
	SCP_1100740	Glutathione-independent glyoxalase DJ-1. (203 aa)
	SCP_1002600	Protein ABC1 homolog, mitochondrial. (644 aa)
	SCP_1004420	Uncharacterized aminotransferase. (466 aa)
	SCP_0901330	Uncharacterized protein. (279 aa)
	SCP_0900830	F-box domain-containing protein. (445 aa)
	COQ3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (350 aa)
	SCP_0902800	Nitronate monooxygenase. (349 aa)
	SCP_0902180	Glutathione-independent glyoxalase HSP31. (227 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (567 aa)
	SCP_0803990	Alpha/beta-hydrolase. (311 aa)
	SCP_0801070	Probable NADPH:adrenodoxin oxidoreductase. (493 aa)
	SCP_0703760	NAD/NADP-dependent indole-3-acetaldehyde reductase. (307 aa)
	SCP_0703920	Uncharacterized protein. (194 aa)
	SCP_0703910	Uncharacterized protein. (174 aa)
	SCP_0606460	F-box domain-containing protein. (437 aa)
	SCP_0606300	NADPH-dependent conjugated polyketone reductase C1. (303 aa)

Your Current Organism:

Sparassis crispa

NCBI taxonomy Id: 139825
Other names: S. crispa

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA4	BNA5	A0A401GIK2	A0A401GII3	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.984
BNA4	COQ3	A0A401GIK2	A0A401GW87	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.506
BNA4	COQ5	A0A401GIK2	A0A401GM31	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.420
BNA4	SCP_0209510	A0A401GIK2	A0A401GC64	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized aminotransferase.	0.802
BNA4	SCP_0305810	A0A401GIK2	A0A401GFF9	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.414
BNA4	SCP_0412030	A0A401GIK2	A0A401GKW8	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized methyltransferase.	0.506
BNA4	SCP_0803990	A0A401GIK2	A0A401GUG3	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Alpha/beta-hydrolase.	0.874
BNA4	SCP_0901330	A0A401GIK2	A0A401GWW2	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized protein.	0.506
BNA4	SCP_1004420	A0A401GIK2	A0A401GY88	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Uncharacterized aminotransferase.	0.802
BNA4	SCP_1202800	A0A401GIK2	A0A401H0U5	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	Indoleamine 2,3-dioxygenase.	0.554
BNA5	BNA4	A0A401GII3	A0A401GIK2	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.984
BNA5	COQ6	A0A401GII3	A0A401GVN9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.560
BNA5	SCP_0209510	A0A401GII3	A0A401GC64	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized aminotransferase.	0.803
BNA5	SCP_0305810	A0A401GII3	A0A401GFF9	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein.	0.988
BNA5	SCP_0803990	A0A401GII3	A0A401GUG3	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Alpha/beta-hydrolase.	0.870
BNA5	SCP_1004420	A0A401GII3	A0A401GY88	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized aminotransferase.	0.803
BNA5	SCP_1202800	A0A401GII3	A0A401H0U5	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Indoleamine 2,3-dioxygenase.	0.899
COQ3	BNA4	A0A401GW87	A0A401GIK2	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.506
COQ3	COQ4	A0A401GW87	A0A401H0N5	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	0.622
COQ3	COQ5	A0A401GW87	A0A401GM31	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.699