node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DRE2 | SCP_0109960 | A0A401GBY6 | A0A401G7I0 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Biotin synthase. | 0.422 |
DRE2 | SCP_0110300 | A0A401GBY6 | A0A401G7L3 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Frataxin homolog, mitochondrial. | 0.447 |
DRE2 | SCP_0205740 | A0A401GBY6 | A0A401GB19 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.501 |
DRE2 | SCP_0902320 | A0A401GBY6 | A0A401GVY9 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.938 |
DRE2 | SCP_1101570 | A0A401GBY6 | A0A401GZA5 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Uncharacterized bolA-like protein; Belongs to the BolA/IbaG family. | 0.853 |
DRE2 | SCP_1800740 | A0A401GBY6 | A0A401H6L1 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | Monothiol glutaredoxin-4. | 0.954 |
SCP_0109960 | DRE2 | A0A401G7I0 | A0A401GBY6 | Biotin synthase. | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.422 |
SCP_0109960 | SCP_0115560 | A0A401G7I0 | A0A401G920 | Biotin synthase. | Iron-sulfur assembly protein. | 0.428 |
SCP_0109960 | SCP_0205740 | A0A401G7I0 | A0A401GB19 | Biotin synthase. | Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.443 |
SCP_0109960 | SCP_0308940 | A0A401G7I0 | A0A401GG59 | Biotin synthase. | Dihydroxy-acid dehydratase. | 0.470 |
SCP_0109960 | SCP_0701920 | A0A401G7I0 | A0A401GS16 | Biotin synthase. | Dihydroxy-acid dehydratase. | 0.470 |
SCP_0110300 | DRE2 | A0A401G7L3 | A0A401GBY6 | Frataxin homolog, mitochondrial. | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.447 |
SCP_0110300 | SCP_0113320 | A0A401G7L3 | A0A401G8H9 | Frataxin homolog, mitochondrial. | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | 0.522 |
SCP_0110300 | SCP_0115560 | A0A401G7L3 | A0A401G920 | Frataxin homolog, mitochondrial. | Iron-sulfur assembly protein. | 0.566 |
SCP_0110300 | SCP_0203700 | A0A401G7L3 | A0A401GAK1 | Frataxin homolog, mitochondrial. | Electron transfer protein 1, mitochondrial. | 0.829 |
SCP_0110300 | SCP_0205740 | A0A401G7L3 | A0A401GB19 | Frataxin homolog, mitochondrial. | Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. | 0.999 |
SCP_0110300 | SCP_0507420 | A0A401G7L3 | A0A401GN96 | Frataxin homolog, mitochondrial. | Adrenodoxin homolog, mitochondrial. | 0.843 |
SCP_0110300 | SCP_0509950 | A0A401G7L3 | A0A401GNZ8 | Frataxin homolog, mitochondrial. | Iron-sulfur assembly protein. | 0.570 |
SCP_0110300 | SCP_0606350 | A0A401G7L3 | A0A401GR15 | Frataxin homolog, mitochondrial. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.679 |
SCP_0110300 | SCP_0902320 | A0A401G7L3 | A0A401GVY9 | Frataxin homolog, mitochondrial. | Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.547 |