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SCP_0111450 SCP_0111450 SCP_0116180 SCP_0116180 SCP_0202290 SCP_0202290 SCP_0701590 SCP_0701590 SCP_0601320 SCP_0601320 SCP_0506770 SCP_0506770 SCP_0506780 SCP_0506780 SCP_0505720 SCP_0505720 SCP_0410980 SCP_0410980 SCP_0701970 SCP_0701970 SCP_0407650 SCP_0407650 SCP_0309120 SCP_0309120 SCP_0303860 SCP_0303860 SCP_0213650 SCP_0213650 SCP_0211280 SCP_0211280 SCP_0209030 SCP_0209030 SCP_0208440 SCP_0208440 SCP_0205580 SCP_0205580 SCP_0202750 SCP_0202750 SCP_0702720 SCP_0702720 SCP_0703260 SCP_0703260 SCP_0803280 SCP_0803280 SCP_0803460 SCP_0803460 SCP_0901510 SCP_0901510 SCP_0100080 SCP_0100080 SCP_0103460 SCP_0103460 SCP_0106750 SCP_0106750 SCP_1002210 SCP_1002210 SCP_1101480 SCP_1101480 SCP_1102080 SCP_1102080 SCP_1303530 SCP_1303530 SCP_1602100 SCP_1602100 SCP_0108080 SCP_0108080 SCP_0108990 SCP_0108990 SCP_0109980 SCP_0109980
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SCP_0111450NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (353 aa)
SCP_0116180Poly [ADP-ribose] polymerase. (625 aa)
SCP_0202290Malate dehydrogenase. (337 aa)
SCP_0701590NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (242 aa)
SCP_0601320NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (497 aa)
SCP_0506770tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. (673 aa)
SCP_0506780UDP-glucose 6-dehydrogenase. (469 aa)
SCP_0505720Malate dehydrogenase. (334 aa)
SCP_0410980Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (472 aa)
SCP_0701970Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...] (320 aa)
SCP_04076503-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (344 aa)
SCP_0309120NADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family. (227 aa)
SCP_0303860Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (386 aa)
SCP_0213650Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (547 aa)
SCP_02112803-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (383 aa)
SCP_0209030Histidine biosynthesis trifunctional protein. (855 aa)
SCP_0208440Ferredoxin reductase-like C-terminal NADP-linked domain-containing protein. (358 aa)
SCP_0205580S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (379 aa)
SCP_0202750Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (545 aa)
SCP_0702720NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1056 aa)
SCP_0703260NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (292 aa)
SCP_0803280Dihydrolipoyl dehydrogenase. (505 aa)
SCP_0803460NAD-dependent protein deacylase; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (298 aa)
SCP_0901510Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (663 aa)
SCP_0100080NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (327 aa)
SCP_0103460NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. (484 aa)
SCP_0106750Glycerol-3-phosphate dehydrogenase [NAD(+)]. (368 aa)
SCP_1002210Glyceraldehyde-3-phosphate dehydrogenase. (337 aa)
SCP_1101480Uncharacterized protein. (304 aa)
SCP_1102080Adenosylhomocysteinase. (430 aa)
SCP_1303530Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (358 aa)
SCP_1602100ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (349 aa)
SCP_0108080Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (368 aa)
SCP_0108990D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (467 aa)
SCP_0109980Probable NADH-ubiquinone oxidoreductase 30.4 kDa subunit; Belongs to the complex I 30 kDa subunit family. (272 aa)
Your Current Organism:
Sparassis crispa
NCBI taxonomy Id: 139825
Other names: S. crispa
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