(14 nodes) Valine, leucine and isoleucine biosynthesis network (Aspergillus parasiticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P875_00042931	Uncharacterized protein. (407 aa)
	P875_00042488	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
	P875_00042385	Uncharacterized protein. (622 aa)
	P875_00033937	Thr-dehyd. (378 aa)
	P875_00034229	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
	P875_00095454	Dehydratase family protein. (608 aa)
	P875_00034117	Uncharacterized protein. (380 aa)
	P875_00010847	Acetolactate synthase. (690 aa)
	P875_00127683	Small subunit of acetolactate synthase. (322 aa)
	P875_00021406	PALP domain-containing protein. (1106 aa)
	P875_00127746	Threonine dehydratase. (567 aa)
	P875_00116994	Dehydratase family protein. (702 aa)
	P875_00127721	Pyridoxal-phosphate dependent enzyme. (438 aa)
	P875_00127566	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (412 aa)

Your Current Organism:

Aspergillus parasiticus

NCBI taxonomy Id: 1403190
Other names: A. parasiticus SU-1, Aspergillus parasiticus SU-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
P875_00010847	P875_00021406	A0A0F0IDW4	A0A0F0IH28	Acetolactate synthase.	PALP domain-containing protein.	0.819
P875_00010847	P875_00033937	A0A0F0IDW4	A0A0F0I7U3	Acetolactate synthase.	Thr-dehyd.	0.922
P875_00010847	P875_00034117	A0A0F0IDW4	A0A0F0IAR9	Acetolactate synthase.	Uncharacterized protein.	0.782
P875_00010847	P875_00034229	A0A0F0IDW4	A0A0F0I880	Acetolactate synthase.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.948
P875_00010847	P875_00042385	A0A0F0IDW4	A0A0F0I2W4	Acetolactate synthase.	Uncharacterized protein.	0.673
P875_00010847	P875_00042488	A0A0F0IDW4	A0A0F0I0L0	Acetolactate synthase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.782
P875_00010847	P875_00042931	A0A0F0IDW4	A0A0F0HZG5	Acetolactate synthase.	Uncharacterized protein.	0.782
P875_00010847	P875_00095454	A0A0F0IDW4	A0A0F0I8N2	Acetolactate synthase.	Dehydratase family protein.	0.876
P875_00010847	P875_00116994	A0A0F0IDW4	A0A0F0ILH6	Acetolactate synthase.	Dehydratase family protein.	0.734
P875_00010847	P875_00127566	A0A0F0IDW4	A0A0F0IMD6	Acetolactate synthase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.816
P875_00010847	P875_00127683	A0A0F0IDW4	A0A0F0IGS0	Acetolactate synthase.	Small subunit of acetolactate synthase.	0.998
P875_00010847	P875_00127721	A0A0F0IDW4	A0A0F0IM12	Acetolactate synthase.	Pyridoxal-phosphate dependent enzyme.	0.925
P875_00010847	P875_00127746	A0A0F0IDW4	A0A0F0IIC3	Acetolactate synthase.	Threonine dehydratase.	0.936
P875_00021406	P875_00010847	A0A0F0IH28	A0A0F0IDW4	PALP domain-containing protein.	Acetolactate synthase.	0.819
P875_00021406	P875_00033937	A0A0F0IH28	A0A0F0I7U3	PALP domain-containing protein.	Thr-dehyd.	0.550
P875_00021406	P875_00034117	A0A0F0IH28	A0A0F0IAR9	PALP domain-containing protein.	Uncharacterized protein.	0.957
P875_00021406	P875_00034229	A0A0F0IH28	A0A0F0I880	PALP domain-containing protein.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.623
P875_00021406	P875_00042385	A0A0F0IH28	A0A0F0I2W4	PALP domain-containing protein.	Uncharacterized protein.	0.835
P875_00021406	P875_00042488	A0A0F0IH28	A0A0F0I0L0	PALP domain-containing protein.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.957
P875_00021406	P875_00042931	A0A0F0IH28	A0A0F0HZG5	PALP domain-containing protein.	Uncharacterized protein.	0.938