(31 nodes) Mixed, incl. Molybdenum cofactor biosynthesis, and Protein maturation by iron-sulfur cluster transfer network (Aspergillus parasiticus)

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second shell of interactors

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proteins of unknown 3D structure

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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Your Input:
	P875_00042504	SufA. (236 aa)
	P875_00053231	CsdA. (461 aa)
	P875_00095254	BolA-like protein; Belongs to the BolA/IbaG family. (129 aa)
	P875_00095653	ThiF family protein. (394 aa)
	P875_00034198	Elp3 domain-containing protein. (1307 aa)
	P875_00033909	CsdA. (436 aa)
	P875_00011207	MOSC domain-containing protein. (349 aa)
	P875_00010549	Scaffold protein Nfu/NifU N terminal. (804 aa)
	P875_00010328	Iron-sulfur cluster assembly accessory protein. (237 aa)
	P875_00010049	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (450 aa)
	P875_00021831	GRXPICOTlike. (269 aa)
	P875_00010324	Frataxin. (210 aa)
	P875_00021950	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (706 aa)
	P875_00010967	GloB. (292 aa)
	P875_00021939	Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (1320 aa)
	P875_00117423	Rhodanese-like domain protein. (503 aa)
	cnxH	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (194 aa)
	P875_00108926	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (704 aa)
	uba4	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (495 aa)
	P875_00127554	Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (151 aa)
	P875_00116960	Aminotransferase class-V. (197 aa)
	P875_00076268	Aminotransferase class-V. (454 aa)
	P875_00075822	Aminotransferase class-V. (439 aa)
	P875_00076187	Aminotransferase class-V. (609 aa)
	P875_00127614	NifU-like N terminal domain protein. (160 aa)
	P875_00117173	BolA-like protein; Belongs to the BolA/IbaG family. (107 aa)
	P875_00109054	Complex1LYR-like protein; Belongs to the complex I LYR family. (1075 aa)
	cnxH-2	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (179 aa)
	P875_00108940	Polysaccharide deacetylase. (431 aa)
	P875_00108627	Aminotransferase class-V. (513 aa)
	P875_00076209	TLD like protein. (549 aa)

Your Current Organism:

Aspergillus parasiticus

NCBI taxonomy Id: 1403190
Other names: A. parasiticus SU-1, Aspergillus parasiticus SU-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
P875_00010049	P875_00011207	A0A0F0ID98	A0A0F0I9Z0	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	MOSC domain-containing protein.	0.662
P875_00010049	P875_00021950	A0A0F0ID98	A0A0F0IFP6	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	0.907
P875_00010049	P875_00034198	A0A0F0ID98	A0A0F0I8D8	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Elp3 domain-containing protein.	0.872
P875_00010049	P875_00095653	A0A0F0ID98	A0A0F0I8A0	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	ThiF family protein.	0.635
P875_00010049	P875_00108926	A0A0F0ID98	A0A0F0IJB8	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	0.851
P875_00010049	P875_00108940	A0A0F0ID98	A0A0F0IPK4	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Polysaccharide deacetylase.	0.854
P875_00010049	cnxH	A0A0F0ID98	A0A0F0IJ43	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.	0.903
P875_00010049	cnxH-2	A0A0F0ID98	A0A0F0IPH1	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.	0.675
P875_00010049	uba4	A0A0F0ID98	A0A0F0IJF5	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.683
P875_00010324	P875_00010328	A0A0F0IF90	A0A0F0ICB8	Frataxin.	Iron-sulfur cluster assembly accessory protein.	0.484
P875_00010324	P875_00010549	A0A0F0IF90	A0A0F0IBU0	Frataxin.	Scaffold protein Nfu/NifU N terminal.	0.656
P875_00010324	P875_00021831	A0A0F0IF90	A0A0F0IEB6	Frataxin.	GRXPICOTlike.	0.447
P875_00010324	P875_00033909	A0A0F0IF90	A0A0F0I932	Frataxin.	CsdA.	0.873
P875_00010324	P875_00042504	A0A0F0IF90	A0A0F0I0H7	Frataxin.	SufA.	0.499
P875_00010324	P875_00053231	A0A0F0IF90	A0A0F0I3K6	Frataxin.	CsdA.	0.873
P875_00010324	P875_00075822	A0A0F0IF90	A0A0F0ILT5	Frataxin.	Aminotransferase class-V.	0.873
P875_00010324	P875_00076187	A0A0F0IF90	A0A0F0IMA9	Frataxin.	Aminotransferase class-V.	0.873
P875_00010324	P875_00076268	A0A0F0IF90	A0A0F0IKC9	Frataxin.	Aminotransferase class-V.	0.873
P875_00010324	P875_00108627	A0A0F0IF90	A0A0F0IQE8	Frataxin.	Aminotransferase class-V.	0.999
P875_00010324	P875_00109054	A0A0F0IF90	A0A0F0IPD1	Frataxin.	Complex1LYR-like protein; Belongs to the complex I LYR family.	0.998