Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aflO | aflP | Q9UQY0 | Q12120 | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | 0.870 |
| aflO | aflQ | Q9UQY0 | O13345 | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | 0.669 |
| aflO | aflR | Q9UQY0 | Q6UEG8 | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | 0.662 |
| aflO | aflS | Q9UQY0 | O42716 | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | 0.433 |
| aflP | aflO | Q12120 | Q9UQY0 | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | 0.870 |
| aflP | aflQ | Q12120 | O13345 | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | 0.958 |
| aflP | aflR | Q12120 | Q6UEG8 | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | 0.738 |
| aflP | aflS | Q12120 | O42716 | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | 0.455 |
| aflQ | aflO | O13345 | Q9UQY0 | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | 0.669 |
| aflQ | aflP | O13345 | Q12120 | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | 0.958 |
| aflQ | aflR | O13345 | Q6UEG8 | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | 0.662 |
| aflQ | aflS | O13345 | O42716 | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | 0.489 |
| aflR | aflO | Q6UEG8 | Q9UQY0 | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | 0.662 |
| aflR | aflP | Q6UEG8 | Q12120 | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | 0.738 |
| aflR | aflQ | Q6UEG8 | O13345 | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | 0.662 |
| aflR | aflS | Q6UEG8 | O42716 | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | 0.787 |
| aflS | aflO | O42716 | Q9UQY0 | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | Demethylsterigmatocystin 6-O-methyltransferase; Demethylsterigmatocystin 6-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as wel [...] | 0.433 |
| aflS | aflP | O42716 | Q12120 | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | Sterigmatocystin 8-O-methyltransferase; Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS afl [...] | 0.455 |
| aflS | aflQ | O42716 | O13345 | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | O-methylsterigmatocystin oxidoreductase; O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2). The first step of the pathway is the conversion of acetate to norsolorinic acid (NOR) and requires the fatty acid synthase subunits aflA and aflB, as well as the PKS a [...] | 0.489 |
| aflS | aflR | O42716 | Q6UEG8 | Aflatoxin cluster transcriptional coactivator aflS; Transcription coactivator involved in regulation of the aflatoxin biosynthesis gene cluster with aflR. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 biosynthesis. AflJ may act in aflR transport to or from the nucleus, thus controlling the availability of af [...] | Aflatoxin biosynthesis regulatory protein; Transcription factor involved in regulation of the aflatoxin biosynthesis gene cluster. Binds with its co-regulator aflS to AFLR1 elements (5'-TCGSWNNSCGR-3') present in the promoters of the aflatoxin cluster genes. The ratio of the expression data between aflS:aflR plays a crucial role in the regulation of aflatoxins production. A high ratio, produced at a range between 17 and 30 degrees Celsius, corresponds with the production profile of aflatoxin G1 biosynthesis. A low ratio, produced over 30 degrees Celsius, is related to aflatoxin B1 bios [...] | 0.787 |