(13 nodes) Cell redox homeostasis network (Aspergillus parasiticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P875_00021593	OYEYqiMFMN. (439 aa)
	P875_00042580	Dihydrolipoyl dehydrogenase. (512 aa)
	P875_00053021	OYEYqiMFMN. (456 aa)
	P875_00095233	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (182 aa)
	P875_00034205	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (562 aa)
	P875_00086589	NADH:flavin oxidoreductase / NADH oxidase family protein. (420 aa)
	P875_00011152	OYEYqiMFMN. (421 aa)
	P875_00021598	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (166 aa)
	P875_00108569	NADH:flavin oxidoreductase / NADH oxidase family protein. (434 aa)
	P875_00076150	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (168 aa)
	P875_00108645	AhpC/TSA family protein. (267 aa)
	P875_00128068	Pyridine nucleotide-disulfide oxidoreductase. (334 aa)
	P875_00127557	AhpC/TSA family protein. (207 aa)

Your Current Organism:

Aspergillus parasiticus

NCBI taxonomy Id: 1403190
Other names: A. parasiticus SU-1, Aspergillus parasiticus SU-1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
P875_00011152	P875_00128068	A0A0F0IC05	A0A0F0IHH3	OYEYqiMFMN.	Pyridine nucleotide-disulfide oxidoreductase.	0.460
P875_00021593	P875_00128068	A0A0F0IHS1	A0A0F0IHH3	OYEYqiMFMN.	Pyridine nucleotide-disulfide oxidoreductase.	0.460
P875_00021598	P875_00034205	A0A0F0IER8	A0A0F0I5A2	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.716
P875_00021598	P875_00042580	A0A0F0IER8	A0A0F0I0B7	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Dihydrolipoyl dehydrogenase.	0.693
P875_00021598	P875_00076150	A0A0F0IER8	A0A0F0IMD1	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.891
P875_00021598	P875_00095233	A0A0F0IER8	A0A0F0I478	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.547
P875_00021598	P875_00108645	A0A0F0IER8	A0A0F0ILT9	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	AhpC/TSA family protein.	0.738
P875_00034205	P875_00021598	A0A0F0I5A2	A0A0F0IER8	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.716
P875_00034205	P875_00076150	A0A0F0I5A2	A0A0F0IMD1	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.716
P875_00034205	P875_00095233	A0A0F0I5A2	A0A0F0I478	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.768
P875_00034205	P875_00108645	A0A0F0I5A2	A0A0F0ILT9	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	AhpC/TSA family protein.	0.931
P875_00034205	P875_00127557	A0A0F0I5A2	A0A0F0IGX8	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	AhpC/TSA family protein.	0.444
P875_00034205	P875_00128068	A0A0F0I5A2	A0A0F0IHH3	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	Pyridine nucleotide-disulfide oxidoreductase.	0.895
P875_00042580	P875_00021598	A0A0F0I0B7	A0A0F0IER8	Dihydrolipoyl dehydrogenase.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.693
P875_00042580	P875_00076150	A0A0F0I0B7	A0A0F0IMD1	Dihydrolipoyl dehydrogenase.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.693
P875_00042580	P875_00095233	A0A0F0I0B7	A0A0F0I478	Dihydrolipoyl dehydrogenase.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.693
P875_00042580	P875_00108645	A0A0F0I0B7	A0A0F0ILT9	Dihydrolipoyl dehydrogenase.	AhpC/TSA family protein.	0.686
P875_00042580	P875_00127557	A0A0F0I0B7	A0A0F0IGX8	Dihydrolipoyl dehydrogenase.	AhpC/TSA family protein.	0.435
P875_00042580	P875_00128068	A0A0F0I0B7	A0A0F0IHH3	Dihydrolipoyl dehydrogenase.	Pyridine nucleotide-disulfide oxidoreductase.	0.879
P875_00053021	P875_00128068	A0A0F0I2C0	A0A0F0IHH3	OYEYqiMFMN.	Pyridine nucleotide-disulfide oxidoreductase.	0.460