(44 nodes) Butanoate metabolism network (Aspergillus parasiticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P875_00053319	FadB. (609 aa)
	P875_00042704	Putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (466 aa)
	P875_00042558	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (292 aa)
	P875_00053321	3-hydroxy-3-methylglutaryl-CoA lyase catalytic TIM barrel domain protein. (350 aa)
	P875_00053359	Uncharacterized protein. (334 aa)
	P875_00086528	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (963 aa)
	P875_00086406	AMP-binding enzyme. (700 aa)
	P875_00042768	Acetoacetyl-CoA synthetase acetoacetate-CoA ligase AACS. (244 aa)
	P875_00042733	Uncharacterized protein. (321 aa)
	P875_00095290	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (518 aa)
	P875_00095251	Aldehyde dehydrogenase family protein. (519 aa)
	P875_00095227	3-hydroxyacyl-CoA dehydrogenase NAD binding domain protein. (320 aa)
	P875_00064937	AMP-binding enzyme. (688 aa)
	P875_00086396	Pyridoxal-dependent decarboxylase conserved domain protein. (576 aa)
	P875_00095370	Aldehyde dehydrogenase family protein. (131 aa)
	P875_00138398	Thiamine pyrophosphate enzyme C-terminal TPP binding domain protein; Belongs to the TPP enzyme family. (586 aa)
	P875_00138378	Alpha-acetolactate decarboxylase. (157 aa)
	P875_00138252	Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (498 aa)
	P875_00034469	Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (498 aa)
	P875_00064992	Uncharacterized protein. (130 aa)
	P875_00065018	3-hydroxyacyl-CoA dehydrogenase NAD binding domain protein. (601 aa)
	P875_00138389	Zinc-binding dehydrogenase. (365 aa)
	P875_00010745	Pyridoxal-dependent decarboxylase conserved domain protein. (570 aa)
	P875_00010530	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (504 aa)
	P875_00010524	DAO domain-containing protein. (464 aa)
	P875_00010038	DadA. (515 aa)
	P875_00022153	FadB. (813 aa)
	P875_00010847	Acetolactate synthase. (690 aa)
	P875_00010489	Salicylaldehyde dehydrogenase DoxF-like protein. (481 aa)
	P875_00022151	3HCDH_N domain-containing protein. (227 aa)
	P875_00022169	FadB. (606 aa)
	P875_00022160	Fungal transcription factor regulatory middle homology region. (679 aa)
	P875_00127756	Succinate-semialdehyde dehydrogenase. (498 aa)
	P875_00010814	3-hydroxy-3-methylglutaryl-CoA-synthase. (286 aa)
	P875_00021521	GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	P875_00127683	Small subunit of acetolactate synthase. (322 aa)
	P875_00117303	Aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family. (466 aa)
	P875_00010062	Fungal transcription factor regulatory middle homology region. (1016 aa)
	P875_00021982	2R3R-23-butanediol dehydrogenase. (351 aa)
	P875_00108957	Aldehyde dehydrogenase family protein. (499 aa)
	P875_00076323	Coenzyme A transferase. (1088 aa)
	P875_00117216	Aldehyde dehydrogenase family protein. (499 aa)
	P875_00117290	Hydroxymethylglutaryl-coenzyme A synthase C terminal. (233 aa)
	P875_00109026	FAD dependent oxidoreductase. (532 aa)

Your Current Organism:

Aspergillus parasiticus

NCBI taxonomy Id: 1403190
Other names: A. parasiticus SU-1, Aspergillus parasiticus SU-1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
P875_00010062	P875_00010847	A0A0F0IIH9	A0A0F0IDW4	Fungal transcription factor regulatory middle homology region.	Acetolactate synthase.	0.421
P875_00010062	P875_00021521	A0A0F0IIH9	A0A0F0IGN8	Fungal transcription factor regulatory middle homology region.	GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.508
P875_00010062	P875_00021982	A0A0F0IIH9	A0A0F0IJ78	Fungal transcription factor regulatory middle homology region.	2R3R-23-butanediol dehydrogenase.	0.419
P875_00010062	P875_00042768	A0A0F0IIH9	A0A0F0I307	Fungal transcription factor regulatory middle homology region.	Acetoacetyl-CoA synthetase acetoacetate-CoA ligase AACS.	0.557
P875_00010062	P875_00053321	A0A0F0IIH9	A0A0F0I1G9	Fungal transcription factor regulatory middle homology region.	3-hydroxy-3-methylglutaryl-CoA lyase catalytic TIM barrel domain protein.	0.449
P875_00010062	P875_00064937	A0A0F0IIH9	A0A0F0I775	Fungal transcription factor regulatory middle homology region.	AMP-binding enzyme.	0.557
P875_00010062	P875_00086406	A0A0F0IIH9	A0A0F0I2Q2	Fungal transcription factor regulatory middle homology region.	AMP-binding enzyme.	0.557
P875_00010062	P875_00086528	A0A0F0IIH9	A0A0F0I2H6	Fungal transcription factor regulatory middle homology region.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.405
P875_00010062	P875_00138252	A0A0F0IIH9	A0A0F0I977	Fungal transcription factor regulatory middle homology region.	Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.709
P875_00010062	P875_00138389	A0A0F0IIH9	A0A0F0IAR0	Fungal transcription factor regulatory middle homology region.	Zinc-binding dehydrogenase.	0.419
P875_00010062	P875_00138398	A0A0F0IIH9	A0A0F0I930	Fungal transcription factor regulatory middle homology region.	Thiamine pyrophosphate enzyme C-terminal TPP binding domain protein; Belongs to the TPP enzyme family.	0.421
P875_00010489	P875_00010847	A0A0F0IEN9	A0A0F0IDW4	Salicylaldehyde dehydrogenase DoxF-like protein.	Acetolactate synthase.	0.421
P875_00010489	P875_00021521	A0A0F0IEN9	A0A0F0IGN8	Salicylaldehyde dehydrogenase DoxF-like protein.	GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.508
P875_00010489	P875_00021982	A0A0F0IEN9	A0A0F0IJ78	Salicylaldehyde dehydrogenase DoxF-like protein.	2R3R-23-butanediol dehydrogenase.	0.419
P875_00010489	P875_00042768	A0A0F0IEN9	A0A0F0I307	Salicylaldehyde dehydrogenase DoxF-like protein.	Acetoacetyl-CoA synthetase acetoacetate-CoA ligase AACS.	0.557
P875_00010489	P875_00053321	A0A0F0IEN9	A0A0F0I1G9	Salicylaldehyde dehydrogenase DoxF-like protein.	3-hydroxy-3-methylglutaryl-CoA lyase catalytic TIM barrel domain protein.	0.449
P875_00010489	P875_00064937	A0A0F0IEN9	A0A0F0I775	Salicylaldehyde dehydrogenase DoxF-like protein.	AMP-binding enzyme.	0.557
P875_00010489	P875_00086406	A0A0F0IEN9	A0A0F0I2Q2	Salicylaldehyde dehydrogenase DoxF-like protein.	AMP-binding enzyme.	0.557
P875_00010489	P875_00086528	A0A0F0IEN9	A0A0F0I2H6	Salicylaldehyde dehydrogenase DoxF-like protein.	Glutamate decarboxylase; Belongs to the group II decarboxylase family.	0.405
P875_00010489	P875_00138252	A0A0F0IEN9	A0A0F0I977	Salicylaldehyde dehydrogenase DoxF-like protein.	Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.709