(14 nodes) Nicotinate and nicotinamide metabolism network (Acinetobacter sp. TGLY2)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AMW80284.1	Nicotinate-nucleotide diphosphorylase (carboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (282 aa)
	AMW77887.1	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
	AMW77888.1	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)
	AMW77889.1	NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (480 aa)
	nadA	Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (355 aa)
	nadE	NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (541 aa)
	AMW78289.1	NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	ppnK	NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (313 aa)
	AMW78436.1	Nicotinamide-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
	AMW80349.1	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (545 aa)
	AMW79046.1	NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
	AMW79337.1	NAD(P)(+) transhydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
	pncB	Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (402 aa)
	AMW80209.1	Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)

Your Current Organism:

Acinetobacter sp. TGLY2

NCBI taxonomy Id: 1407071
Other names: A. sp. TGL-Y2, Acinetobacter sp. TGL-Y2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMW77887.1	AMW77888.1	AMD27_02575	AMD27_02580	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMW77887.1	AMW77889.1	AMD27_02575	AMD27_02585	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.999
AMW77887.1	AMW78289.1	AMD27_02575	AMD27_04915	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMW77887.1	AMW78436.1	AMD27_02575	AMD27_05750	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinamide-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMW77887.1	AMW79046.1	AMD27_02575	AMD27_09200	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
AMW77887.1	AMW79337.1	AMD27_02575	AMD27_10795	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(P)(+) transhydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.906
AMW77887.1	nadE	AMD27_02575	AMD27_04600	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.906
AMW77887.1	ppnK	AMD27_02575	AMD27_05250	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.910
AMW77888.1	AMW77887.1	AMD27_02580	AMD27_02575	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMW77888.1	AMW77889.1	AMD27_02580	AMD27_02585	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	0.999
AMW77888.1	AMW78289.1	AMD27_02580	AMD27_04915	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMW77888.1	AMW78436.1	AMD27_02580	AMD27_05750	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nicotinamide-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMW77888.1	AMW79046.1	AMD27_02580	AMD27_09200	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD-dependent protein deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.903
AMW77888.1	AMW79337.1	AMD27_02580	AMD27_10795	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(P)(+) transhydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
AMW77888.1	nadE	AMD27_02580	AMD27_04600	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.	0.906
AMW77888.1	ppnK	AMD27_02580	AMD27_05250	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.911
AMW77889.1	AMW77887.1	AMD27_02585	AMD27_02575	NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMW77889.1	AMW77888.1	AMD27_02585	AMD27_02580	NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AMW77889.1	AMW78289.1	AMD27_02585	AMD27_04915	NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AMW77889.1	AMW78436.1	AMD27_02585	AMD27_05750	NAD synthetase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.	Nicotinamide-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901