27 items (Halobacterium hubeiense) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	HHUB_1033	Peptidase M20 family protein. (409 aa)
	citB1	Aconitate hydratase; Gene: hly; product: serine protease halolysin (nonfunctional); EC_number: 3.4.21.-; gene has a frameshift. (661 aa)
	HHUB_1134	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase). (363 aa)
	dapE	Succinyl-diaminopimelate desuccinylase. (356 aa)
	pabC	Aminodeoxychorismate lyase. (284 aa)
	aspC4	Pyridoxal phosphate-dependent aminotransferase. (368 aa)
	aspC3	Pyridoxal phosphate-dependent aminotransferase. (380 aa)
	aspC2	Pyridoxal phosphate-dependent aminotransferase. (373 aa)
	aspC6	Pyridoxal phosphate-dependent aminotransferase. (385 aa)
	asd	Aspartate-semialdehyde dehydrogenase. (343 aa)
	leuB1	3-isopropylmalate dehydrogenase. (329 aa)
	leuD	3-isopropylmalate dehydratase small subunit. (204 aa)
	leuC	3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (474 aa)
	ilvC	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (350 aa)
	ilvN	Acetolactate synthase small subunit. (209 aa)
	ilvB	Acetolactate synthase large subunit. (590 aa)
	leuA1	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (399 aa)
	ilvD	Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (586 aa)
	icd	Isocitrate dehydrogenase (NADP). (419 aa)
	citZ	Citrate synthase. (378 aa)
	ilvE	Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa)
	argX	Probable glutamate--argW ligase. (288 aa)
	argC	N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (346 aa)
	argB	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (278 aa)
	argD	Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (370 aa)
	argE	Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (336 aa)
	lysC	Aspartate kinase; Belongs to the aspartokinase family. (394 aa)

Your Current Organism:

Halobacterium hubeiense

NCBI taxonomy Id: 1407499
Other names: H. hubeiense, HAMBI 3616, Halobacterium sp. JI20-1, strain JI20-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HHUB_1033	HHUB_1134	HHUB_1033	HHUB_1134	Peptidase M20 family protein.	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase).	0.929
HHUB_1033	argC	HHUB_1033	HHUB_3649	Peptidase M20 family protein.	N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.	0.567
HHUB_1033	argE	HHUB_1033	HHUB_3652	Peptidase M20 family protein.	Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.	0.966
HHUB_1033	dapE	HHUB_1033	HHUB_1586	Peptidase M20 family protein.	Succinyl-diaminopimelate desuccinylase.	0.926
HHUB_1134	HHUB_1033	HHUB_1134	HHUB_1033	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase).	Peptidase M20 family protein.	0.929
HHUB_1134	argB	HHUB_1134	HHUB_3650	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase).	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	0.426
HHUB_1134	argC	HHUB_1134	HHUB_3649	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase).	N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.	0.573
HHUB_1134	argE	HHUB_1134	HHUB_3652	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase).	Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.	0.926
HHUB_1134	dapE	HHUB_1134	HHUB_1586	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase).	Succinyl-diaminopimelate desuccinylase.	0.921
argB	HHUB_1134	HHUB_3650	HHUB_1134	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Peptidase M20 family protein (homolog to succinyl-diaminopimelate desuccinylase).	0.426
argB	argC	HHUB_3650	HHUB_3649	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.	0.999
argB	argD	HHUB_3650	HHUB_3651	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.	0.999
argB	argE	HHUB_3650	HHUB_3652	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.	0.992
argB	argX	HHUB_3650	HHUB_3648	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Probable glutamate--argW ligase.	0.998
argB	asd	HHUB_3650	HHUB_2863	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Aspartate-semialdehyde dehydrogenase.	0.446
argB	dapE	HHUB_3650	HHUB_1586	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Succinyl-diaminopimelate desuccinylase.	0.454
argB	ilvB	HHUB_3650	HHUB_3056	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Acetolactate synthase large subunit.	0.403
argB	leuA1	HHUB_3650	HHUB_3057	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.433
argB	leuB1	HHUB_3650	HHUB_3050	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	3-isopropylmalate dehydrogenase.	0.456
argB	lysC	HHUB_3650	HHUB_3743	Acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	Aspartate kinase; Belongs to the aspartokinase family.	0.528