node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPB1 | T310_0349 | A0A0F4Z1B0 | A0A0F4Z5M4 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Ribosomal biogenesis protein Gar2. | 0.993 |
SPB1 | T310_0418 | A0A0F4Z1B0 | A0A0F4Z6M7 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Ribosome biogenesis protein NSA2. | 0.980 |
SPB1 | T310_0579 | A0A0F4Z1B0 | A0A0F4Z5M7 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Protein MAK16; Belongs to the MAK16 family. | 0.982 |
SPB1 | T310_1447 | A0A0F4Z1B0 | A0A0F4Z378 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Uncharacterized protein. | 0.971 |
SPB1 | T310_1583 | A0A0F4Z1B0 | A0A0F4Z3E3 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | 60S ribosomal subunit biogenesis protein Nop16. | 0.984 |
SPB1 | T310_2372 | A0A0F4Z1B0 | A0A0F4YZP9 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | RNA helicase. | 0.985 |
SPB1 | T310_2748 | A0A0F4Z1B0 | A0A0F4YYU6 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Ribosome assembly protein Noc2. | 0.989 |
SPB1 | T310_2901 | A0A0F4Z1B0 | A0A0F4YXI7 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | C2H2-type domain-containing protein. | 0.461 |
SPB1 | T310_3527 | A0A0F4Z1B0 | A0A0F4YXU2 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | CCAAT-box-binding transcription factor. | 0.892 |
SPB1 | T310_3731 | A0A0F4Z1B0 | A0A0F4YWM5 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | 60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. | 0.970 |
SPB1 | T310_3732 | A0A0F4Z1B0 | A0A0F4YVD1 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. | 0.980 |
SPB1 | T310_3859 | A0A0F4Z1B0 | A0A0F4YV68 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. | 0.890 |
SPB1 | T310_4153 | A0A0F4Z1B0 | A0A0F4YU46 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Uncharacterized protein. | 0.527 |
SPB1 | T310_5424 | A0A0F4Z1B0 | A0A0F4YQL6 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | RNA-binding protein required for biogenesis of the ribosomal 60S subunit. | 0.862 |
SPB1 | T310_6098 | A0A0F4Z1B0 | A0A0F4YNS8 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | RNA helicase. | 0.989 |
SPB1 | T310_6648 | A0A0F4Z1B0 | A0A0F4YND7 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | ATP-dependent RNA helicase DBP10. | 0.939 |
SPB1 | T310_7555 | A0A0F4Z1B0 | A0A0F4YK40 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Ribosome biogenesis protein. | 0.972 |
SPB1 | T310_7874 | A0A0F4Z1B0 | A0A0F4YJ94 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | DEAD/DEAH box helicase. | 0.823 |
SPB1 | T310_7930 | A0A0F4Z1B0 | A0A0F4YIT2 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | Ribosome biogenesis protein RLP24. | 0.990 |
SPB1 | T310_9098 | A0A0F4Z1B0 | A0A0F4YHW4 | AdoMet-dependent rRNA methyltransferase SPB1; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. | 60S ribosome biogenesis protein Brx1. | 0.862 |