STRINGSTRING
fbaA fbaA gapA gapA pgk pgk gpmA gpmA pfkA pfkA tpiA tpiA rpiB rpiB tktB tktB tkt tkt pfkA-2 pfkA-2 pykF pykF rpe rpe eno eno pgi pgi
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fbaAFructose-bisphosphate aldolase. (331 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (415 aa)
gpmAPhosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa)
rpiBRibose 5-phosphate epimerase. (153 aa)
tktBPutative transketolase N-terminal section. (275 aa)
tktPutative transketolase C-terminal section. (315 aa)
pfkA-2Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 2; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (557 aa)
pykFPyruvate kinase; Belongs to the pyruvate kinase family. (341 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (215 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa)
pgiGlucosephosphate isomerase; Belongs to the GPI family. (547 aa)
Your Current Organism:
Endomicrobium proavitum
NCBI taxonomy Id: 1408281
Other names: Candidatus Endomicrobium sp. Rsa215, DSM 29378, E. proavitum, Endomicrobium proavitum Zheng et al. 2018, JCM 30189, JCM 32103, strain Rsa215
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.