STRINGSTRING
glyA glyA metY metY metH metH metH-2 metH-2 yfdZ yfdZ trpB-2 trpB-2 ilvB ilvB iscS-2 iscS-2 hisC hisC aatA aatA alr alr glgP glgP Epro_0161 Epro_0161 dxs dxs bioF bioF Epro_0337 Epro_0337 acpP acpP nrdE nrdE metC metC Epro_0689 Epro_0689 patB patB iscS iscS dapL dapL lysA lysA argD argD thrC thrC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
metYO-acetylhomoserine (thiol)-lyase. (429 aa)
metHPutative cobalamin-dependent methionine synthase. (202 aa)
metH-2Homocysteine S-methyltransferase. (805 aa)
yfdZLL-diaminopimelate aminotransferase. (400 aa)
trpB-2Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (455 aa)
ilvBAcetolactate synthase III, large subunit. (578 aa)
iscS-2Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent. (416 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (373 aa)
aatAAspartate aminotransferase. (401 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (391 aa)
glgPAlpha-glucan phosphorylase. (867 aa)
Epro_0161Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (228 aa)
dxs1-deoxyxylulose-5-phosphate synthase, thiamine-requiring, FAD-requiring; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (617 aa)
bioF8-amino-7-oxononanoate synthase. (397 aa)
Epro_03372-oxoglutarate synthase beta subunit. (247 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa)
nrdERibonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (769 aa)
metCO-acetylhomoserine (thiol)-lyase. (434 aa)
Epro_0689Cystathionine beta-lyase. (388 aa)
patBCystathionine beta-lyase PatB. (390 aa)
iscSCysteine desulfurase. (394 aa)
dapLLL-diaminopimelate aminotransferase. (386 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (412 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (390 aa)
thrCThreonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (355 aa)
Your Current Organism:
Endomicrobium proavitum
NCBI taxonomy Id: 1408281
Other names: Candidatus Endomicrobium sp. Rsa215, DSM 29378, E. proavitum, Endomicrobium proavitum Zheng et al. 2018, JCM 30189, JCM 32103, strain Rsa215
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