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| | kdsC | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. (179 aa) |
| | accD | acetyl-CoA carboxylase, beta (carboxyltransferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (269 aa) |
| | Epro_0401 | Putative Heptosyltransferase II. (381 aa) |
| | Epro_0399 | Putative membrane-associated phospholipid phosphatase. (709 aa) |
| | fabF | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (79 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | fabD | malonyl-CoA-[acyl-carrier-protein] transacylase. (309 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (336 aa) |
| | plsX | phosphate:acyl-ACP acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (344 aa) |
| | waaJ | UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase. (295 aa) |
| | Epro_0323 | Hypothetical protein. (233 aa) |
| | waaF-2 | ADP-heptose:LPS heptosyltransferase II. (361 aa) |
| | waaF | ADP-heptose:LPS heptosyltransferase II. (361 aa) |
| | Epro_0320 | Hypothetical protein. (384 aa) |
| | lpxL | Lipid A biosynthesis acyltransferase. (302 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (357 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (362 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (388 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Belongs to the CDS family. (263 aa) |
| | Epro_0249 | Exported protein of unknown function. (143 aa) |
| | lpxK | Putative Tetraacyldisaccharide 4-kinase, lipid A 4kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (339 aa) |
| | dxs | 1-deoxyxylulose-5-phosphate synthase, thiamine-requiring, FAD-requiring; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (617 aa) |
| | ispA | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. (295 aa) |
| | rfaK-2 | Putative ADP-heptose--lipopolysaccharide heptosyltransferase. (339 aa) |
| | rfaK | Lipopolysaccharide heptosyltransferase. (354 aa) |
| | suhB | Inositol-1-monophosphatase. (260 aa) |
| | tibC | Glycosyltransferase TibC. (452 aa) |
| | lpxP | Putative Lipid A biosynthesis acyltransferase. (300 aa) |
| | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (275 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (241 aa) |
| | Epro_0059 | LPS biosynthesis glycosyltransferase. (248 aa) |
| | accA | acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (352 aa) |
| | lpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (445 aa) |
| | lpxA | UDP-N-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (256 aa) |
| | lpxA-2 | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (262 aa) |
| | Epro_0453 | Hypothetical protein. (266 aa) |
| | lpxB | Putative Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (362 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (275 aa) |
| | psd | Phosphatidylserine decarboxylase. (207 aa) |
| | pssA | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (270 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (332 aa) |
| | plsY | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (214 aa) |
| | rfaF | Lipopolysaccharide heptosyltransferase II. (312 aa) |
| | waaC | Lipopolysaccharide heptosyltransferase I. (308 aa) |
| | kdtA | Three-deoxy-d-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (426 aa) |
| | pgsA | CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (210 aa) |
| | accB | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (154 aa) |
| | tibC-2 | Glycosyltransferase TibC. (452 aa) |
| | Epro_0764 | Tetratricopeptide domain-containing protein. (342 aa) |
| | Epro_0827 | Putative metallophosphoesterase. (366 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase; Belongs to the P-Pant transferase superfamily. (111 aa) |
| | Epro_0876 | Exported protein of unknown function. (165 aa) |
| | Epro_0935 | Beta-ketoacyl-acyl-carrier-protein synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (395 aa) |
| | acpP-2 | Acyl carrier protein. (85 aa) |
| | Epro_0937 | Putative Lipid A biosynthesis acyltransferase. (298 aa) |
| | Epro_0941 | Putative (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase. (113 aa) |
| | Epro_0947 | Putative Phospholipid/glycerol acyltransferase. (237 aa) |
| | acpP-3 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (84 aa) |
| | Epro_0949 | Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa) |
| | Epro_0950 | Putative All-trans-retinol 13,14-reductase. (468 aa) |
| | Epro_1007 | Putative Glycosyl transferase, family 9. (421 aa) |
| | Epro_1008 | Membrane protein of unknown function. (699 aa) |
| | accB-2 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase. (139 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (283 aa) |
| | glmU | Bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (454 aa) |
| | Epro_1221 | Putative Acyl-ACP thioesterase. (242 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (156 aa) |
| | ispD | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (217 aa) |
| | waaX | Putative beta1,4-galactosyltransferase. (266 aa) |
| | cls | Cardiolipin synthase. (486 aa) |
| | plsC | 1-acylglycerol-3-phosphate O-acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (197 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (287 aa) |
| | lpxD | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (346 aa) |
