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lysA lysA Epro_0765 Epro_0765 argB argB Epro_0775 Epro_0775 Epro_0781 Epro_0781 ribF ribF Epro_0811 Epro_0811 yhaA yhaA Epro_0887 Epro_0887 ftsQ-2 ftsQ-2 argC argC nadD nadD Epro_1017 Epro_1017 metY metY bioB bioB Epro_1167 Epro_1167 Epro_1181 Epro_1181 iscS-2 iscS-2 ispE ispE Epro_1249 Epro_1249 Epro_1257 Epro_1257 acs acs adk adk ychF ychF tadA tadA Epro_0047 Epro_0047 Epro_0071 Epro_0071 nth nth Epro_0228 Epro_0228 fieF fieF nfo nfo tktB tktB guaD guaD argA argA Epro_0344 Epro_0344 acdA acdA etfA etfA gltB-2 gltB-2 purF purF ptpS ptpS Epro_0393 Epro_0393 Epro_0470 Epro_0470 ada ada leuA leuA truA truA nspC nspC ybeY ybeY hnh hnh purD purD metC metC nifH nifH glnA-2 glnA-2 Epro_0709 Epro_0709 iscS iscS yqgF yqgF folK folK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (412 aa)
Epro_0765Patatin. (317 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (249 aa)
Epro_0775Hypothetical protein. (138 aa)
Epro_0781Hypothetical protein. (179 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (289 aa)
Epro_0811Hypothetical protein. (190 aa)
yhaAAmidohydrolase. (381 aa)
Epro_0887Pyruvate carboxyltransferase. (457 aa)
ftsQ-2Cell division protein FtsQ. (158 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (340 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (195 aa)
Epro_1017RNA-metabolising metallo-beta-lactamase. (505 aa)
metYO-acetylhomoserine (thiol)-lyase. (429 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (331 aa)
Epro_1167Alpha-isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (521 aa)
Epro_1181Putative acetyltransferase. (162 aa)
iscS-2Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent. (416 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (283 aa)
Epro_1249Hypothetical protein. (286 aa)
Epro_1257Conserved membrane protein of unknown function. (189 aa)
acsAMP-dependent synthetase and ligase. (552 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (209 aa)
ychFPutative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa)
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (169 aa)
Epro_0047Conserved membrane protein of unknown function. (205 aa)
Epro_0071Metallo-beta-lactamase superfamily 1 protein. (273 aa)
nthDNA glycosylase and apyrimidinic (AP) lyase (endonuclease III); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (212 aa)
Epro_0228Radical SAM domain protein. (358 aa)
fieFPutative cation efflux family protein, CzcD-like; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (312 aa)
nfoPutative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (282 aa)
tktBPutative transketolase N-terminal section. (275 aa)
guaDCytidine/deoxycytidylate deaminase, zinc-binding region. (158 aa)
argAPutative N-acetyltransferase; Belongs to the acetyltransferase family. (152 aa)
Epro_0344Class V aminotransferase. (377 aa)
acdAAcyl-CoA dehydrogenase. (389 aa)
etfAElectron transfer flavoprotein subunit alpha. (401 aa)
gltB-2Archaeal glutamate synthase [NADPH]; Belongs to the glutamate synthase family. (501 aa)
purFAmidophosphoribosyltransferase 2, chloroplastic; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (456 aa)
ptpS6-pyruvoyl tetrahydrobiopterin synthase. (123 aa)
Epro_0393Ferredoxin thioredoxin reductase subunit beta. (202 aa)
Epro_0470Putative Amine oxidase family protein. (427 aa)
adaPutative methylated-DNA--protein-cysteine methyltransferase. (130 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (509 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (244 aa)
nspCCarboxynorspermidine/carboxyspermidine decarboxylase. (368 aa)
ybeYEndoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (138 aa)
hnhHNH endonuclease. (358 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (424 aa)
metCO-acetylhomoserine (thiol)-lyase. (434 aa)
nifHNitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (291 aa)
glnA-2Glutamine synthetase. (698 aa)
Epro_0709Hypothetical protein. (253 aa)
iscSCysteine desulfurase. (394 aa)
yqgFPutative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (137 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (176 aa)
Your Current Organism:
Endomicrobium proavitum
NCBI taxonomy Id: 1408281
Other names: Candidatus Endomicrobium sp. Rsa215, DSM 29378, E. proavitum, Endomicrobium proavitum Zheng et al. 2018, JCM 30189, JCM 32103, strain Rsa215
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