31 items (Pneumocystis jirovecii RU7) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Predicted Interactions

gene neighborhood

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Your Input:
	T551_01538	CUE domain-containing protein. (913 aa)
	T551_03650	Uncharacterized protein. (1052 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (303 aa)
	T551_03429	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	T551_03015	Uncharacterized protein. (307 aa)
	T551_03048	Uncharacterized protein. (719 aa)
	T551_02840	ENDO3c domain-containing protein. (337 aa)
	T551_02864	RPOL9 domain-containing protein. (103 aa)
	T551_02613	Uncharacterized protein. (103 aa)
	T551_02761	Uncharacterized protein. (339 aa)
	T551_02401	UV excision repair protein Rad23. (369 aa)
	T551_02081	Uncharacterized protein. (69 aa)
	T551_02136	Uncharacterized protein. (248 aa)
	T551_02170	Uncharacterized protein. (265 aa)
	T551_02213	Uncharacterized protein. (732 aa)
	T551_01969	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (708 aa)
	T551_01988	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (447 aa)
	T551_02044	DNA polymerase. (1088 aa)
	T551_01770	CDK-activating kinase assembly factor MAT1. (326 aa)
	T551_01849	DNA repair protein. (297 aa)
	T551_01564	CULLIN_2 domain-containing protein; Belongs to the cullin family. (820 aa)
	T551_01210	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (598 aa)
	T551_01314	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2179 aa)
	T551_01049	DNA repair helicase rad15. (784 aa)
	T551_01103	Uncharacterized protein. (1045 aa)
	T551_01119	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (457 aa)
	T551_01178	Uncharacterized protein. (762 aa)
	T551_05052	RPA_C domain-containing protein. (294 aa)
	T551_00133	Uncharacterized protein. (844 aa)
	T551_00213	Uncharacterized protein. (1024 aa)
	T551_00218	ERCC4 domain-containing protein. (919 aa)

Your Current Organism:

Pneumocystis jirovecii RU7

NCBI taxonomy Id: 1408657
Other names: P. jirovecii RU7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NTH1	T551_00133	A0A0W4ZD52	A0A0W4ZW87	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Uncharacterized protein.	0.423
NTH1	T551_00218	A0A0W4ZD52	A0A0W4ZWI9	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	ERCC4 domain-containing protein.	0.811
NTH1	T551_01049	A0A0W4ZD52	A0A0W4ZTS7	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	DNA repair helicase rad15.	0.426
NTH1	T551_01103	A0A0W4ZD52	A0A0W4ZTX8	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Uncharacterized protein.	0.558
NTH1	T551_01314	A0A0W4ZD52	A0A0W4ZS83	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.471
NTH1	T551_01849	A0A0W4ZD52	A0A0W4ZQC6	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	DNA repair protein.	0.611
NTH1	T551_01969	A0A0W4ZD52	A0A0W4ZNR9	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family.	0.598
NTH1	T551_02044	A0A0W4ZD52	A0A0W4ZP06	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	DNA polymerase.	0.547
NTH1	T551_02136	A0A0W4ZD52	A0A0W4ZME3	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Uncharacterized protein.	0.525
NTH1	T551_02401	A0A0W4ZD52	A0A0W4ZL82	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	UV excision repair protein Rad23.	0.412
NTH1	T551_02840	A0A0W4ZD52	A0A0W4ZHM5	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	ENDO3c domain-containing protein.	0.672
NTH1	T551_03650	A0A0W4ZD52	A0A0W4ZBN9	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	Uncharacterized protein.	0.644
T551_00133	NTH1	A0A0W4ZW87	A0A0W4ZD52	Uncharacterized protein.	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.	0.423
T551_00133	T551_00213	A0A0W4ZW87	A0A0W4ZWI0	Uncharacterized protein.	Uncharacterized protein.	0.631
T551_00133	T551_00218	A0A0W4ZW87	A0A0W4ZWI9	Uncharacterized protein.	ERCC4 domain-containing protein.	0.870
T551_00133	T551_01049	A0A0W4ZW87	A0A0W4ZTS7	Uncharacterized protein.	DNA repair helicase rad15.	0.999
T551_00133	T551_01103	A0A0W4ZW87	A0A0W4ZTX8	Uncharacterized protein.	Uncharacterized protein.	0.836
T551_00133	T551_01119	A0A0W4ZW87	A0A0W4ZTZ6	Uncharacterized protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.999
T551_00133	T551_01178	A0A0W4ZW87	A0A0W4ZU58	Uncharacterized protein.	Uncharacterized protein.	0.631
T551_00133	T551_01210	A0A0W4ZW87	A0A0W4ZRX6	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.675