69 items (Pneumocystis jirovecii RU7) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T551_01638	Uncharacterized protein. (182 aa)
	T551_03526	Uncharacterized protein. (407 aa)
	T551_03557	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (405 aa)
	T551_03564	Uncharacterized protein. (699 aa)
	T551_03587	Protein kinase domain-containing protein. (1017 aa)
	T551_03553	Uncharacterized protein. (180 aa)
	T551_03594	Uncharacterized protein. (1083 aa)
	T551_03421	Uncharacterized protein. (1617 aa)
	T551_03373	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (264 aa)
	T551_03336	Uncharacterized protein. (404 aa)
	T551_03115	Ras-like protein. (208 aa)
	T551_03122	Exo84_C domain-containing protein. (631 aa)
	T551_03243	Uncharacterized protein; Belongs to the actin family. (419 aa)
	T551_02967	Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (319 aa)
	T551_03011	UNC45-central domain-containing protein. (843 aa)
	T551_03017	Uncharacterized protein; Belongs to the actin family. (431 aa)
	T551_02846	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (353 aa)
	T551_02887	Uncharacterized protein. (328 aa)
	T551_02655	BAR domain-containing protein. (246 aa)
	T551_02674	ENTH domain-containing protein. (592 aa)
	T551_02691	Uncharacterized protein. (173 aa)
	T551_02757	HECT domain-containing protein. (1003 aa)
	T551_02329	DUF2013 domain-containing protein. (417 aa)
	T551_02083	Actin-2; Belongs to the actin family. (385 aa)
	T551_02138	Uncharacterized protein. (291 aa)
	T551_02120	WH2 domain-containing protein. (347 aa)
	T551_02161	Uncharacterized protein. (1056 aa)
	T551_02110	Calponin-homology (CH) domain-containing protein. (178 aa)
	T551_02240	Uncharacterized protein. (148 aa)
	T551_02255	SH3 domain-containing protein. (951 aa)
	T551_01994	Uncharacterized protein. (629 aa)
	T551_01671	Uncharacterized protein. (788 aa)
	T551_01780	ENTH domain-containing protein. (613 aa)
	T551_01805	DH domain-containing protein. (1067 aa)
	T551_01831	Uncharacterized protein. (1233 aa)
	T551_01842	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (190 aa)
	T551_01467	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (182 aa)
	T551_01470	Calmodulin; Belongs to the calmodulin family. (168 aa)
	T551_01521	Uncharacterized protein. (374 aa)
	T551_01540	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2300 aa)
	T551_01249	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (346 aa)
	T551_01277	Profilin; Belongs to the profilin family. (127 aa)
	T551_01287	Actin-1. (383 aa)
	T551_00962	Uncharacterized protein. (774 aa)
	T551_00949	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1572 aa)
	T551_00973	Uncharacterized protein. (656 aa)
	T551_01062	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1175 aa)
	T551_01047	MHD domain-containing protein. (765 aa)
	T551_01061	Protein kinase domain-containing protein. (676 aa)
	T551_00636	Uncharacterized protein. (798 aa)
	T551_00666	AIP3 domain-containing protein. (823 aa)
	T551_00759	Uncharacterized protein. (451 aa)
	T551_00757	RRM domain-containing protein. (683 aa)
	T551_00718	DH domain-containing protein. (595 aa)
	T551_00809	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (366 aa)
	T551_00399	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (270 aa)
	T551_00423	Serine/threonine-protein phosphatase. (529 aa)
	T551_00480	IPPc domain-containing protein. (1178 aa)
	T551_00504	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1669 aa)
	T551_00499	Uncharacterized protein. (1135 aa)
	T551_00519	Uncharacterized protein. (1242 aa)
	T551_00524	Uncharacterized protein. (161 aa)
	T551_00011	TYR_PHOSPHATASE_2 domain-containing protein. (513 aa)
	T551_00092	Uncharacterized protein. (206 aa)
	T551_00128	WD_REPEATS_REGION domain-containing protein. (609 aa)
	T551_00242	Uncharacterized protein. (587 aa)
	T551_00274	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
	T551_00268	Uncharacterized protein. (490 aa)
	T551_00318	Uncharacterized protein. (808 aa)

Your Current Organism:

Pneumocystis jirovecii RU7

NCBI taxonomy Id: 1408657
Other names: P. jirovecii RU7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T551_00011	T551_00504	A0A0W4ZVX6	A0A0W4ZVL0	TYR_PHOSPHATASE_2 domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.764
T551_00011	T551_00718	A0A0W4ZVX6	A0A0W4ZUM8	TYR_PHOSPHATASE_2 domain-containing protein.	DH domain-containing protein.	0.498
T551_00011	T551_00962	A0A0W4ZVX6	A0A0W4ZTJ0	TYR_PHOSPHATASE_2 domain-containing protein.	Uncharacterized protein.	0.719
T551_00011	T551_01467	A0A0W4ZVX6	A0A0W4ZRC1	TYR_PHOSPHATASE_2 domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.586
T551_00011	T551_01470	A0A0W4ZVX6	A0A0W4ZRC9	TYR_PHOSPHATASE_2 domain-containing protein.	Calmodulin; Belongs to the calmodulin family.	0.429
T551_00011	T551_01540	A0A0W4ZVX6	A0A0W4ZRJ1	TYR_PHOSPHATASE_2 domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.539
T551_00011	T551_01638	A0A0W4ZVX6	A0A0W4ZRW6	TYR_PHOSPHATASE_2 domain-containing protein.	Uncharacterized protein.	0.407
T551_00011	T551_02161	A0A0W4ZVX6	A0A0W4ZME0	TYR_PHOSPHATASE_2 domain-containing protein.	Uncharacterized protein.	0.547
T551_00011	T551_02240	A0A0W4ZVX6	A0A0W4ZMM8	TYR_PHOSPHATASE_2 domain-containing protein.	Uncharacterized protein.	0.429
T551_00011	T551_03115	A0A0W4ZVX6	A0A0W4ZFF5	TYR_PHOSPHATASE_2 domain-containing protein.	Ras-like protein.	0.411
T551_00011	T551_03421	A0A0W4ZVX6	A0A0W4ZDN9	TYR_PHOSPHATASE_2 domain-containing protein.	Uncharacterized protein.	0.443
T551_00092	T551_00274	A0A0W4ZW94	A0A0W4ZWN9	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.999
T551_00092	T551_00759	A0A0W4ZW94	A0A0W4ZUL2	Uncharacterized protein.	Uncharacterized protein.	0.908
T551_00092	T551_00809	A0A0W4ZW94	A0A0W4ZUT6	Uncharacterized protein.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	0.999
T551_00092	T551_01062	A0A0W4ZW94	A0A0W4ZTT8	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.525
T551_00092	T551_01287	A0A0W4ZW94	A0A0W4ZS78	Uncharacterized protein.	Actin-1.	0.929
T551_00092	T551_01540	A0A0W4ZW94	A0A0W4ZRJ1	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.549
T551_00092	T551_01842	A0A0W4ZW94	A0A0W4ZQC0	Uncharacterized protein.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.999
T551_00092	T551_02083	A0A0W4ZW94	A0A0W4ZM78	Uncharacterized protein.	Actin-2; Belongs to the actin family.	0.837
T551_00092	T551_02120	A0A0W4ZW94	A0A0W4ZMC7	Uncharacterized protein.	WH2 domain-containing protein.	0.655