36 items (Pneumocystis jirovecii RU7) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	T551_03070	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (343 aa)
	T551_03429	Checkpoint protein; Belongs to the HUS1 family. (285 aa)
	T551_03271	Uncharacterized protein. (681 aa)
	T551_03385	Uncharacterized protein. (887 aa)
	T551_03071	Uncharacterized protein. (1474 aa)
	T551_02613	Uncharacterized protein. (103 aa)
	T551_02735	WD_REPEATS_REGION domain-containing protein. (570 aa)
	T551_02729	DUF2439 domain-containing protein. (222 aa)
	T551_02280	Uncharacterized protein. (586 aa)
	T551_02347	Uncharacterized protein. (796 aa)
	T551_02420	Zf-primase domain-containing protein. (490 aa)
	T551_02352	Helicase ATP-binding domain-containing protein. (856 aa)
	T551_02136	Uncharacterized protein. (248 aa)
	T551_02211	RECA_2 domain-containing protein. (350 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (811 aa)
	T551_01965	SAE2 domain-containing protein. (647 aa)
	T551_01692	Uncharacterized protein. (1093 aa)
	T551_01551	Uncharacterized protein. (673 aa)
	T551_01579	Uncharacterized protein. (616 aa)
	T551_01580	RBR-type E3 ubiquitin transferase. (510 aa)
	T551_01210	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (598 aa)
	T551_01250	Uncharacterized protein. (535 aa)
	T551_01300	DNA polymerase. (1411 aa)
	T551_01358	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (416 aa)
	T551_01354	Uncharacterized protein. (379 aa)
	T551_01165	Uncharacterized protein. (837 aa)
	T551_00791	AAA_23 domain-containing protein. (1131 aa)
	T551_00792	Protein kinase domain-containing protein. (520 aa)
	T551_00788	Uncharacterized protein. (303 aa)
	T551_00790	DNA repair protein rad50. (172 aa)
	T551_00873	Uncharacterized protein. (985 aa)
	T551_05052	RPA_C domain-containing protein. (294 aa)
	T551_00414	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (497 aa)
	T551_00086	Uncharacterized protein. (282 aa)
	T551_00124	TP6A_N domain-containing protein. (412 aa)
	T551_00269	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (603 aa)

Your Current Organism:

Pneumocystis jirovecii RU7

NCBI taxonomy Id: 1408657
Other names: P. jirovecii RU7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PIF1	T551_00269	A0A0W4ZNJ0	A0A0W4ZWN5	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.751
PIF1	T551_00790	A0A0W4ZNJ0	A0A0W4ZUR2	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DNA repair protein rad50.	0.627
PIF1	T551_00791	A0A0W4ZNJ0	A0A0W4ZUP7	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	AAA_23 domain-containing protein.	0.627
PIF1	T551_00792	A0A0W4ZNJ0	A0A0W4ZUQ1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Protein kinase domain-containing protein.	0.476
PIF1	T551_01210	A0A0W4ZNJ0	A0A0W4ZRX6	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.895
PIF1	T551_01250	A0A0W4ZNJ0	A0A0W4ZS24	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.851
PIF1	T551_01300	A0A0W4ZNJ0	A0A0W4ZS79	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DNA polymerase.	0.514
PIF1	T551_01579	A0A0W4ZNJ0	A0A0W4ZRM6	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.940
PIF1	T551_01692	A0A0W4ZNJ0	A0A0W4ZPV8	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.824
PIF1	T551_02211	A0A0W4ZNJ0	A0A0W4ZMK1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	RECA_2 domain-containing protein.	0.566
PIF1	T551_02347	A0A0W4ZNJ0	A0A0W4ZL24	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.481
PIF1	T551_02352	A0A0W4ZNJ0	A0A0W4ZLB5	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Helicase ATP-binding domain-containing protein.	0.713
PIF1	T551_02420	A0A0W4ZNJ0	A0A0W4ZL89	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Zf-primase domain-containing protein.	0.488
PIF1	T551_03070	A0A0W4ZNJ0	A0A0W4ZGT1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.853
PIF1	T551_03071	A0A0W4ZNJ0	A0A0W4ZGT8	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.984
PIF1	T551_03385	A0A0W4ZNJ0	A0A0W4ZEW9	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.627
PIF1	T551_05052	A0A0W4ZNJ0	A0A0W4ZVC0	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	RPA_C domain-containing protein.	0.666
T551_00124	T551_00269	A0A0W4ZWC1	A0A0W4ZWN5	TP6A_N domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.546
T551_00124	T551_00790	A0A0W4ZWC1	A0A0W4ZUR2	TP6A_N domain-containing protein.	DNA repair protein rad50.	0.721
T551_00124	T551_00791	A0A0W4ZWC1	A0A0W4ZUP7	TP6A_N domain-containing protein.	AAA_23 domain-containing protein.	0.721