16 items (Pneumocystis jirovecii RU7) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T551_01210	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (598 aa)
	T551_01300	DNA polymerase. (1411 aa)
	T551_00843	Uncharacterized protein. (467 aa)
	T551_05052	RPA_C domain-containing protein. (294 aa)
	T551_00005	Uncharacterized protein. (322 aa)
	T551_00535	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (462 aa)
	T551_03135	Uncharacterized protein. (146 aa)
	T551_02820	Uncharacterized protein. (351 aa)
	T551_02613	Uncharacterized protein. (103 aa)
	T551_02622	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (629 aa)
	T551_02469	RRM domain-containing protein. (199 aa)
	T551_02283	Replication factor C subunit 4. (351 aa)
	T551_02170	Uncharacterized protein. (265 aa)
	T551_01874	Uncharacterized protein. (200 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (811 aa)
	T551_02044	DNA polymerase. (1088 aa)

Your Current Organism:

Pneumocystis jirovecii RU7

NCBI taxonomy Id: 1408657
Other names: P. jirovecii RU7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PIF1	T551_00005	A0A0W4ZNJ0	A0A0W4ZVW7	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.418
PIF1	T551_01210	A0A0W4ZNJ0	A0A0W4ZRX6	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.895
PIF1	T551_01300	A0A0W4ZNJ0	A0A0W4ZS79	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DNA polymerase.	0.514
PIF1	T551_01874	A0A0W4ZNJ0	A0A0W4ZNI7	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.612
PIF1	T551_02044	A0A0W4ZNJ0	A0A0W4ZP06	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DNA polymerase.	0.511
PIF1	T551_02469	A0A0W4ZNJ0	A0A0W4ZJT2	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	RRM domain-containing protein.	0.506
PIF1	T551_02622	A0A0W4ZNJ0	A0A0W4ZIK2	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.744
PIF1	T551_05052	A0A0W4ZNJ0	A0A0W4ZVC0	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	RPA_C domain-containing protein.	0.666
T551_00005	PIF1	A0A0W4ZVW7	A0A0W4ZNJ0	Uncharacterized protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.418
T551_00005	T551_00535	A0A0W4ZVW7	A0A0W4ZVP5	Uncharacterized protein.	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	0.653
T551_00005	T551_00843	A0A0W4ZVW7	A0A0W4ZUV7	Uncharacterized protein.	Uncharacterized protein.	0.870
T551_00005	T551_01210	A0A0W4ZVW7	A0A0W4ZRX6	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.611
T551_00005	T551_01300	A0A0W4ZVW7	A0A0W4ZS79	Uncharacterized protein.	DNA polymerase.	0.747
T551_00005	T551_01874	A0A0W4ZVW7	A0A0W4ZNI7	Uncharacterized protein.	Uncharacterized protein.	0.655
T551_00005	T551_02044	A0A0W4ZVW7	A0A0W4ZP06	Uncharacterized protein.	DNA polymerase.	0.867
T551_00005	T551_02283	A0A0W4ZVW7	A0A0W4ZKV3	Uncharacterized protein.	Replication factor C subunit 4.	0.669
T551_00005	T551_02469	A0A0W4ZVW7	A0A0W4ZJT2	Uncharacterized protein.	RRM domain-containing protein.	0.747
T551_00005	T551_02622	A0A0W4ZVW7	A0A0W4ZIK2	Uncharacterized protein.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.642
T551_00005	T551_02820	A0A0W4ZVW7	A0A0W4ZHL0	Uncharacterized protein.	Uncharacterized protein.	0.670
T551_00005	T551_03135	A0A0W4ZVW7	A0A0W4ZFJ3	Uncharacterized protein.	Uncharacterized protein.	0.568