57 items (Pneumocystis jirovecii RU7) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T551_03651	Uncharacterized protein. (687 aa)
	T551_03524	Uncharacterized protein. (1140 aa)
	T551_03558	SGF29 C-terminal domain-containing protein. (270 aa)
	T551_03415	Uncharacterized protein. (321 aa)
	T551_03462	MRG domain-containing protein. (308 aa)
	T551_03290	Uncharacterized protein. (498 aa)
	T551_03299	Uncharacterized protein. (634 aa)
	T551_03331	Uncharacterized protein. (581 aa)
	T551_03128	Uncharacterized protein. (352 aa)
	T551_03225	Uncharacterized protein. (784 aa)
	T551_03233	ARID domain-containing protein. (848 aa)
	T551_03240	Uncharacterized protein. (297 aa)
	T551_03004	Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. (639 aa)
	T551_03064	Uncharacterized protein. (458 aa)
	T551_02839	Uncharacterized protein. (143 aa)
	T551_02643	Uncharacterized protein. (627 aa)
	T551_02538	YL1_C domain-containing protein. (463 aa)
	T551_02543	Uncharacterized protein. (557 aa)
	T551_02380	Uncharacterized protein. (280 aa)
	T551_02073	Uncharacterized protein. (1440 aa)
	T551_02143	GATA-type domain-containing protein. (427 aa)
	SUS1	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...] (104 aa)
	T551_01946	WD_REPEATS_REGION domain-containing protein. (387 aa)
	T551_01934	SET domain-containing protein. (784 aa)
	T551_01669	Uncharacterized protein. (418 aa)
	T551_01820	VEFS-Box domain-containing protein. (565 aa)
	T551_01817	RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (461 aa)
	T551_01485	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (396 aa)
	T551_01550	Uncharacterized protein. (1302 aa)
	T551_01549	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (556 aa)
	T551_01609	Histone H2A; Belongs to the histone H2A family. (132 aa)
	T551_01610	Histone H2B; Belongs to the histone H2B family. (134 aa)
	T551_01628	Histone H2B; Belongs to the histone H2B family. (226 aa)
	T551_01204	40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (247 aa)
	T551_01280	B30.2/SPRY domain-containing protein. (698 aa)
	T551_01275	Negative cofactor 2 complex subunit beta. (137 aa)
	T551_01298	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (531 aa)
	T551_01294	SWIB domain-containing protein. (445 aa)
	T551_01379	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (336 aa)
	T551_00977	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (845 aa)
	T551_01030	Uncharacterized protein. (189 aa)
	T551_01094	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (300 aa)
	T551_01056	Uncharacterized protein. (1167 aa)
	T551_00610	Uncharacterized protein. (231 aa)
	T551_00608	Uncharacterized protein. (299 aa)
	T551_00653	SANT domain-containing protein. (446 aa)
	T551_00736	SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (156 aa)
	T551_00357	Uncharacterized protein. (482 aa)
	T551_00331	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (592 aa)
	T551_00446	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (407 aa)
	T551_00464	Uncharacterized protein. (552 aa)
	T551_00473	Uncharacterized protein. (1598 aa)
	T551_00491	Uncharacterized protein. (224 aa)
	T551_00513	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1050 aa)
	T551_00559	Uncharacterized protein. (773 aa)
	T551_00095	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1247 aa)
	T551_00134	WD_REPEATS_REGION domain-containing protein. (440 aa)

Your Current Organism:

Pneumocystis jirovecii RU7

NCBI taxonomy Id: 1408657
Other names: P. jirovecii RU7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SUS1	T551_00608	A0A0W4ZNG7	A0A0W4ZU72	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Uncharacterized protein.	0.958
SUS1	T551_00736	A0A0W4ZNG7	A0A0W4ZUJ3	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...]	0.998
SUS1	T551_01609	A0A0W4ZNG7	A0A0W4ZRQ9	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Histone H2A; Belongs to the histone H2A family.	0.565
SUS1	T551_01610	A0A0W4ZNG7	A0A0W4ZRS4	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Histone H2B; Belongs to the histone H2B family.	0.505
SUS1	T551_01628	A0A0W4ZNG7	A0A0W4ZRS8	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	Histone H2B; Belongs to the histone H2B family.	0.505
SUS1	T551_03558	A0A0W4ZNG7	A0A0W4ZD31	Transcription and mRNA export factor SUS1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of [...]	SGF29 C-terminal domain-containing protein.	0.997
T551_00095	T551_01549	A0A0W4ZW61	A0A0W4ZRM1	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.998
T551_00095	T551_02380	A0A0W4ZW61	A0A0W4ZL51	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	Uncharacterized protein.	0.853
T551_00095	T551_03128	A0A0W4ZW61	A0A0W4ZFI2	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	Uncharacterized protein.	0.993
T551_00095	T551_03415	A0A0W4ZW61	A0A0W4ZDL9	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	Uncharacterized protein.	0.990
T551_00134	T551_00331	A0A0W4ZW96	A0A0W4ZV74	WD_REPEATS_REGION domain-containing protein.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.827
T551_00134	T551_00357	A0A0W4ZW96	A0A0W4ZV64	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.814
T551_00134	T551_00446	A0A0W4ZW96	A0A0W4ZVG6	WD_REPEATS_REGION domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.908
T551_00134	T551_00464	A0A0W4ZW96	A0A0W4ZVG7	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.714
T551_00134	T551_00473	A0A0W4ZW96	A0A0W4ZVH4	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.938
T551_00134	T551_00513	A0A0W4ZW96	A0A0W4ZVM4	WD_REPEATS_REGION domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.823
T551_00134	T551_00559	A0A0W4ZW96	A0A0W4ZVR8	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.574
T551_00134	T551_00610	A0A0W4ZW96	A0A0W4ZU64	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.815
T551_00134	T551_00977	A0A0W4ZW96	A0A0W4ZTQ7	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.817
T551_00134	T551_01030	A0A0W4ZW96	A0A0W4ZTR6	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.986