STRINGSTRING
gltA gltA AHH15524.1 AHH15524.1 icd icd sdhB sdhB sdhA sdhA sdhD sdhD sdhC sdhC pdhC1 pdhC1 pdhB1 pdhB1 pdhA1 pdhA1 aceE aceE AHH16993.1 AHH16993.1 AHH17065.1 AHH17065.1 pck1 pck1 fumA fumA prpC1 prpC1 acnA acnA AHH19152.1 AHH19152.1 AHH19342.1 AHH19342.1 AHH19343.1 AHH19343.1 mdh mdh AHH19782.1 AHH19782.1 AHH19783.1 AHH19783.1 lpdA2 lpdA2 pdhA2 pdhA2 pdhB2 pdhB2 pdhC2 pdhC2 mqo mqo pyc1 pyc1 pyc2 pyc2 prpC2 prpC2 fumC fumC mqo-2 mqo-2 sucD sucD sucC sucC AHH21887.1 AHH21887.1 pck2 pck2 AHH22318.1 AHH22318.1 AHH22319.1 AHH22319.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gltACitrate synthase; Belongs to the citrate synthase family. (442 aa)
AHH15524.1Putative citrate synthase CitA; Belongs to the citrate synthase family. (380 aa)
icdIsocitrate dehydrogenase; NADP; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (405 aa)
sdhBSuccinate dehydrogenase subunit B. (258 aa)
sdhASuccinate dehydrogenase subunit A. (594 aa)
sdhDSuccinate dehydrogenase subunit D. (143 aa)
sdhCSuccinate dehydrogenase subunit C. (132 aa)
pdhC1Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (455 aa)
pdhB1Pyruvate dehydrogenase E1 component subunit beta. (328 aa)
pdhA1Pyruvate dehydrogenase E1 component subunit alpha. (371 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (971 aa)
AHH16993.12-oxoglutarate dehydrogenase E2 component. (593 aa)
AHH17065.1Citrate synthase-like protein. (395 aa)
pck1Phosphoenolpyruvate carboxykinase Pck; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
fumAPutative fumarate hydratase FumA; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (558 aa)
prpC12-methylcitrate synthase PrpC; Belongs to the citrate synthase family. (374 aa)
acnA2-methylaconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (932 aa)
AHH19152.1Putative aconitate hydratase. (650 aa)
AHH19342.1Putative 2-oxoglutarate oxidoreductase subunit KorB. (359 aa)
AHH19343.1Putative 2-oxoglutarate oxidoreductase subunit KorA. (646 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (335 aa)
AHH19782.1Putative dihydrolipoamide acyltransferase. (402 aa)
AHH19783.1Putative pyruvate dehydrogenase E1 component. (775 aa)
lpdA2Dihydrolipoyl dehydrogenase. (485 aa)
pdhA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (365 aa)
pdhB2Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (330 aa)
pdhC2Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. (395 aa)
mqoPutative malate:quinone oxidoreductase Mqo. (520 aa)
pyc1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1134 aa)
pyc2Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1127 aa)
prpC22-methylcitrate synthase PrpC; Belongs to the citrate synthase family. (374 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
mqo-2Putative malate:quinone oxidoreductase. (471 aa)
sucDsuccinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (304 aa)
sucCsuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
AHH21887.1Dihydrolipoyl dehydrogenase. (467 aa)
pck2Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
AHH22318.1Putative succinate dehydrogenase flavoprotein subunit. (671 aa)
AHH22319.1Putative succinate dehydrogenase/fumarate reductase iron-sulfur protein. (248 aa)
Your Current Organism:
Nocardia nova
NCBI taxonomy Id: 1415166
Other names: N. nova SH22a, Nocardia nova SH22a
Server load: low (22%) [HD]