(10 nodes) DNA-templated transcription, termination, and RNA polymerase network (Streptomyces sp. NRRLB1140)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rho	Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (380 aa)
	nusA	Transcription elongation factor NusA; Participates in both transcription termination and antitermination. (328 aa)
	KOX01477.1	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
	rho-2	Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (685 aa)
	KOV98359.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	nusG	Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (302 aa)
	rpoB	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1161 aa)
	rpoC	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1285 aa)
	rpoA	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa)
	KOV92575.1	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (107 aa)

Your Current Organism:

Streptomyces sp. NRRLB1140

NCBI taxonomy Id: 1415549
Other names: S. sp. NRRL B-1140, Streptomyces sp. NRRL B-1140

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KOV92575.1	KOV98359.1	ADK65_33705	ADK65_21830	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.858
KOV92575.1	KOX01477.1	ADK65_33705	ADK65_09720	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.858
KOV92575.1	nusA	ADK65_33705	ADK65_05570	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription elongation factor NusA; Participates in both transcription termination and antitermination.	0.858
KOV92575.1	nusG	ADK65_33705	ADK65_32115	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination.	0.913
KOV92575.1	rpoA	ADK65_33705	ADK65_32350	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.932
KOV92575.1	rpoB	ADK65_33705	ADK65_32150	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.921
KOV92575.1	rpoC	ADK65_33705	ADK65_32155	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.917
KOV98359.1	KOV92575.1	ADK65_21830	ADK65_33705	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.858
KOV98359.1	nusG	ADK65_21830	ADK65_32115	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination.	0.961
KOV98359.1	rho	ADK65_21830	ADK65_02895	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.	0.879
KOV98359.1	rho-2	ADK65_21830	ADK65_14910	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.	0.879
KOV98359.1	rpoA	ADK65_21830	ADK65_32350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.986
KOV98359.1	rpoB	ADK65_21830	ADK65_32150	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.988
KOV98359.1	rpoC	ADK65_21830	ADK65_32155	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.972
KOX01477.1	KOV92575.1	ADK65_09720	ADK65_33705	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plasmid stabilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.858
KOX01477.1	nusG	ADK65_09720	ADK65_32115	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination.	0.961
KOX01477.1	rho	ADK65_09720	ADK65_02895	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.	0.879
KOX01477.1	rho-2	ADK65_09720	ADK65_14910	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.	0.879
KOX01477.1	rpoA	ADK65_09720	ADK65_32350	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.986
KOX01477.1	rpoB	ADK65_09720	ADK65_32150	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.988