node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KOV93326.1 | KOX00585.1 | ADK65_33095 | ADK65_12955 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.945 |
KOV93326.1 | dnaA | ADK65_33095 | ADK65_13115 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.487 |
KOV94524.1 | KOX00585.1 | ADK65_31470 | ADK65_12955 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.945 |
KOV94524.1 | dnaA | ADK65_31470 | ADK65_13115 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.487 |
KOV97798.1 | KOX00585.1 | ADK65_24555 | ADK65_12955 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.945 |
KOV97798.1 | dnaA | ADK65_24555 | ADK65_13115 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.487 |
KOV99831.1 | KOV99898.1 | ADK65_16990 | ADK65_17050 | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KOV99831.1 | KOX00585.1 | ADK65_16990 | ADK65_12955 | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.579 |
KOV99831.1 | dnaA | ADK65_16990 | ADK65_13115 | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.473 |
KOV99831.1 | gyrB | ADK65_16990 | ADK65_13140 | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.999 |
KOV99831.1 | recF | ADK65_16990 | ADK65_13130 | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.578 |
KOV99831.1 | ychF | ADK65_16990 | ADK65_34790 | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.542 |
KOV99898.1 | KOV99831.1 | ADK65_17050 | ADK65_16990 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
KOV99898.1 | KOX00585.1 | ADK65_17050 | ADK65_12955 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.451 |
KOV99898.1 | KOX00609.1 | ADK65_17050 | ADK65_13135 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family. | 0.546 |
KOV99898.1 | dnaA | ADK65_17050 | ADK65_13115 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.664 |
KOV99898.1 | gyrA | ADK65_17050 | ADK65_13145 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.999 |
KOV99898.1 | recF | ADK65_17050 | ADK65_13130 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.838 |
KOV99898.1 | ychF | ADK65_17050 | ADK65_34790 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.632 |
KOX00585.1 | KOV93326.1 | ADK65_12955 | ADK65_33095 | Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.945 |