(5 nodes) AP endonuclease 1, and Helix-hairpin-helix motif network (Streptomyces sp. NRRLB1140)

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second shell of interactors

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	KOV99490.1	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
	nfo	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (288 aa)
	KOV96039.1	Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
	ung-2	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (222 aa)
	KOV90959.1	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)

Your Current Organism:

Streptomyces sp. NRRLB1140

NCBI taxonomy Id: 1415549
Other names: S. sp. NRRL B-1140, Streptomyces sp. NRRL B-1140

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KOV90959.1	KOV96039.1	ADK65_36460	ADK65_28850	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
KOV90959.1	KOV99490.1	ADK65_36460	ADK65_17670	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.913
KOV90959.1	nfo	ADK65_36460	ADK65_21340	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.958
KOV90959.1	ung-2	ADK65_36460	ADK65_30275	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.987
KOV96039.1	KOV90959.1	ADK65_28850	ADK65_36460	Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
KOV96039.1	KOV99490.1	ADK65_28850	ADK65_17670	Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.970
KOV96039.1	ung-2	ADK65_28850	ADK65_30275	Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.696
KOV99490.1	KOV90959.1	ADK65_17670	ADK65_36460	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.913
KOV99490.1	KOV96039.1	ADK65_17670	ADK65_28850	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.970
KOV99490.1	nfo	ADK65_17670	ADK65_21340	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.960
KOV99490.1	ung-2	ADK65_17670	ADK65_30275	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.987
nfo	KOV90959.1	ADK65_21340	ADK65_36460	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.958
nfo	KOV99490.1	ADK65_21340	ADK65_17670	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.960
nfo	ung-2	ADK65_21340	ADK65_30275	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.972
ung-2	KOV90959.1	ADK65_30275	ADK65_36460	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
ung-2	KOV96039.1	ADK65_30275	ADK65_28850	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.696
ung-2	KOV99490.1	ADK65_30275	ADK65_17670	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
ung-2	nfo	ADK65_30275	ADK65_21340	uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.972