STRINGSTRING
KOV95128.1 KOV95128.1 KOX06368.1 KOX06368.1 KOX06556.1 KOX06556.1 KOX06429.1 KOX06429.1 clpB clpB ruvA ruvA ruvB ruvB KOX05134.1 KOX05134.1 KOX05078.1 KOX05078.1 KOX05100.1 KOX05100.1 KOX04447.1 KOX04447.1 htpG htpG KOX04493.1 KOX04493.1 KOX04506.1 KOX04506.1 KOX03692.1 KOX03692.1 smc smc recG recG KOX03906.1 KOX03906.1 KOX03394.1 KOX03394.1 KOX02603.1 KOX02603.1 clpX clpX KOX02333.1 KOX02333.1 KOX01462.1 KOX01462.1 KOX01118.1 KOX01118.1 KOX01119.1 KOX01119.1 KOX01162.1 KOX01162.1 ftsH ftsH KOX00913.1 KOX00913.1 KOX00914.1 KOX00914.1 KOX01041.1 KOX01041.1 KOX00959.1 KOX00959.1 KOX00585.1 KOX00585.1 KOX00603.1 KOX00603.1 KOX00698.1 KOX00698.1 clpB-2 clpB-2 KOX00281.1 KOX00281.1 KOX00355.1 KOX00355.1 lon lon KOX00121.1 KOX00121.1 KOX00245.1 KOX00245.1 KOW00057.1 KOW00057.1 KOW00081.1 KOW00081.1 KOV99811.1 KOV99811.1 KOV99495.1 KOV99495.1 KOV99505.1 KOV99505.1 uvrA uvrA uvrB uvrB KOV99162.1 KOV99162.1 KOV99083.1 KOV99083.1 KOV98998.1 KOV98998.1 KOV98969.1 KOV98969.1 KOV98680.1 KOV98680.1 KOV98574.1 KOV98574.1 KOV98300.1 KOV98300.1 KOV98440.1 KOV98440.1 KOV98452.1 KOV98452.1 KOV98067.1 KOV98067.1 KOV97992.1 KOV97992.1 KOV97796.1 KOV97796.1 KOV97808.1 KOV97808.1 KOV97719.1 KOV97719.1 KOV97731.1 KOV97731.1 KOV96822.1 KOV96822.1 KOV96949.1 KOV96949.1 KOV96990.1 KOV96990.1 arc arc KOV96050.1 KOV96050.1 KOV95890.1 KOV95890.1 KOV94766.1 KOV94766.1 KOV93485.1 KOV93485.1 KOV93491.1 KOV93491.1 KOV92579.1 KOV92579.1 KOV91597.1 KOV91597.1 ychF ychF KOV90919.1 KOV90919.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KOV95128.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
KOX06368.1Magnesium ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (830 aa)
KOX06556.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
KOX06429.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
clpBProtein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (879 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (356 aa)
KOX05134.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
KOX05078.1CbxX/CfqX; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
KOX05100.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1546 aa)
KOX04447.1Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (800 aa)
htpGHeat shock protein 90; Molecular chaperone. Has ATPase activity. (632 aa)
KOX04493.1Carbonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (749 aa)
KOX04506.1Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (812 aa)
KOX03692.1Topoisomerase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (978 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1187 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (739 aa)
KOX03906.1Heat shock protein 90; Derived by automated computational analysis using gene prediction method: Protein Homology. (612 aa)
KOX03394.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (877 aa)
KOX02603.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
clpXATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (419 aa)
KOX02333.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1443 aa)
KOX01462.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1483 aa)
KOX01118.1ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
KOX01119.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
KOX01162.1Clp protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (679 aa)
KOX00913.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
KOX00914.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
KOX01041.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
KOX00959.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (774 aa)
KOX00585.1Helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (487 aa)
KOX00603.1Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
KOX00698.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
clpB-2ATPase AAA; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (861 aa)
KOX00281.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
KOX00355.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
lonLon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (804 aa)
KOX00121.1Metal-sulfur cluster biosynthetic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
KOX00245.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
KOW00057.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa)
KOW00081.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
KOV99811.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
KOV99495.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (844 aa)
KOV99505.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1021 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (716 aa)
KOV99162.1ABC transporter; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (803 aa)
KOV99083.1Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (767 aa)
KOV98998.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
KOV98969.1Sodium:proton antiporter; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (377 aa)
KOV98680.1Carbonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (745 aa)
KOV98574.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
KOV98300.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
KOV98440.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
KOV98452.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
KOV98067.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
KOV97992.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
KOV97796.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
KOV97808.1Metal ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (797 aa)
KOV97719.1Metal ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (655 aa)
KOV97731.1Phenylacetic acid degradation protein PaaD; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
KOV96822.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
KOV96949.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
KOV96990.1Heat shock protein 90; Derived by automated computational analysis using gene prediction method: Protein Homology. (618 aa)
arcATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (581 aa)
KOV96050.1NDP-hexose 4-ketoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (841 aa)
KOV95890.1Serine-threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
KOV94766.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
KOV93485.1ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (825 aa)
KOV93491.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
KOV92579.1Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (758 aa)
KOV91597.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
ychFGTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (353 aa)
KOV90919.1Cellulose-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
Your Current Organism:
Streptomyces sp. NRRLB1140
NCBI taxonomy Id: 1415549
Other names: S. sp. NRRL B-1140, Streptomyces sp. NRRL B-1140
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