STRINGSTRING
KOX03309.1 KOX03309.1 KOX06278.1 KOX06278.1 KOX06416.1 KOX06416.1 KOX06473.1 KOX06473.1 rnhA rnhA KOX06141.1 KOX06141.1 KOX04371.1 KOX04371.1 KOX04372.1 KOX04372.1 KOX04375.1 KOX04375.1 KOX04394.1 KOX04394.1 pnp pnp KOX03851.1 KOX03851.1 rnhB rnhB KOV98958.1 KOV98958.1 KOV97554.1 KOV97554.1 KOV96776.1 KOV96776.1 KOV96805.1 KOV96805.1 prcB prcB KOV96308.1 KOV96308.1 pafA pafA prcA prcA prcB-2 prcB-2 pup pup KOV96321.1 KOV96321.1 arc arc KOV94758.1 KOV94758.1 xseA xseA xseB xseB rph rph KOX00702.1 KOX00702.1 KOX00878.1 KOX00878.1 KOX00742.1 KOX00742.1 KOX00886.1 KOX00886.1 KOX00127.1 KOX00127.1 KOX00236.1 KOX00236.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KOX03309.1Sugar hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
KOX06278.1Deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
KOX06416.1Alpha-glucuronidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (660 aa)
KOX06473.1alpha-L-arabinofuranosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (237 aa)
KOX06141.11,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology. (696 aa)
KOX04371.1alpha-L-arabinofuranosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
KOX04372.11,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa)
KOX04375.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
KOX04394.1Ricin B lectin; Derived by automated computational analysis using gene prediction method: Protein Homology. (731 aa)
pnpPolynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (753 aa)
KOX03851.1Muramidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (233 aa)
KOV98958.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (899 aa)
KOV97554.11,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 11 (cellulase G) family. (225 aa)
KOV96776.1Xylosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 43 family. (538 aa)
KOV96805.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
prcBProteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. (282 aa)
KOV96308.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (934 aa)
pafAPup--protein ligase; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. (453 aa)
prcAProteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. (235 aa)
prcB-2Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. (258 aa)
pupUbiquitin; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family. (72 aa)
KOV96321.1Pup deamidase/depupylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
arcATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (581 aa)
KOV94758.11,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (402 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (84 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (245 aa)
KOX00702.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
KOX00878.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
KOX00742.1Integrin; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
KOX00886.1Integrin; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
KOX00127.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
KOX00236.1Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 43 family. (492 aa)
Your Current Organism:
Streptomyces sp. NRRLB1140
NCBI taxonomy Id: 1415549
Other names: S. sp. NRRL B-1140, Streptomyces sp. NRRL B-1140
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