STRINGSTRING
KOV93485.1 KOV93485.1 KOX02310.1 KOX02310.1 KOV96326.1 KOV96326.1 KOV96822.1 KOV96822.1 KOV97796.1 KOV97796.1 KOV98263.1 KOV98263.1 KOV98944.1 KOV98944.1 KOV98998.1 KOV98998.1 KOV99811.1 KOV99811.1 KOW00057.1 KOW00057.1 KOX00248.1 KOX00248.1 ku ku KOX00355.1 KOX00355.1 KOX00281.1 KOX00281.1 KOX00961.1 KOX00961.1 KOX00959.1 KOX00959.1 topA topA ku-2 ku-2 KOX02309.1 KOX02309.1 KOX03911.1 KOX03911.1 recG recG ruvA ruvA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KOV93485.1ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (825 aa)
KOX02310.1Molecular chaperone DnaK; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
KOV96326.1Recombinase RecB; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
KOV96822.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
KOV97796.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
KOV98263.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
KOV98944.1Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1118 aa)
KOV98998.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
KOV99811.1DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
KOW00057.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa)
KOX00248.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (85 aa)
kuDNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (346 aa)
KOX00355.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
KOX00281.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
KOX00961.1Integration host factor; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (93 aa)
KOX00959.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (774 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (941 aa)
ku-2DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (301 aa)
KOX02309.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)
KOX03911.1DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (200 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (739 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa)
Your Current Organism:
Streptomyces sp. NRRLB1140
NCBI taxonomy Id: 1415549
Other names: S. sp. NRRL B-1140, Streptomyces sp. NRRL B-1140
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