STRINGSTRING
ligB ligB KOV96326.1 KOV96326.1 KOV98998.1 KOV98998.1 KOV99083.1 KOV99083.1 KOV99162.1 KOV99162.1 polA polA uvrB uvrB uvrA uvrA uvrC uvrC KOV99853.1 KOV99853.1 lexA lexA KOW00057.1 KOW00057.1 KOX00355.1 KOX00355.1 KOX00281.1 KOX00281.1 KOX01060.1 KOX01060.1 KOX00959.1 KOX00959.1 KOX01161.1 KOX01161.1 KOX04447.1 KOX04447.1 KOV96301.1 KOV96301.1 KOV96822.1 KOV96822.1 KOV97826.1 KOV97826.1 KOV97796.1 KOV97796.1 KOV98944.1 KOV98944.1 mfd mfd KOV92579.1 KOV92579.1 KOV93485.1 KOV93485.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ligBATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (512 aa)
KOV96326.1Recombinase RecB; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
KOV98998.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)
KOV99083.1Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (767 aa)
KOV99162.1ABC transporter; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (803 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (888 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (716 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1021 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (694 aa)
KOV99853.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
lexALexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (240 aa)
KOW00057.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (672 aa)
KOX00355.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
KOX00281.1ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
KOX01060.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
KOX00959.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (774 aa)
KOX01161.13'-5' exonuclease; Similar to DNA polymerase I; lacks 5'-3' exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa)
KOX04447.1Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (800 aa)
KOV96301.15'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
KOV96822.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
KOV97826.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
KOV97796.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (679 aa)
KOV98944.1Helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1118 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1177 aa)
KOV92579.1Daunorubicin resistance protein DrrC; Derived by automated computational analysis using gene prediction method: Protein Homology. (758 aa)
KOV93485.1ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (825 aa)
Your Current Organism:
Streptomyces sp. NRRLB1140
NCBI taxonomy Id: 1415549
Other names: S. sp. NRRL B-1140, Streptomyces sp. NRRL B-1140
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