(12 nodes) Pyridine nucleotide-disulphide oxidoreductase, class I, and acetyl-CoA biosynthetic process from pyruvate network (Geosporobacter ferrireducens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOT69215.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
	AOT69761.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (456 aa)
	pdhA	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)
	AOT71040.1	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
	AOT71041.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
	AOT71042.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
	AOT71138.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
	AOT71139.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (473 aa)
	AOT73295.1	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
	AOT72502.1	Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
	AOT72504.1	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
	AOT72505.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)

Your Current Organism:

Geosporobacter ferrireducens

NCBI taxonomy Id: 1424294
Other names: G. ferrireducens, Geosporobacter sp. IRF9, JCM 19987, KCTC 15395, strain IRF9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT69215.1	AOT69761.1	Gferi_06340	Gferi_09290	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.921
AOT69215.1	AOT71040.1	Gferi_06340	Gferi_16635	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.984
AOT69215.1	AOT71041.1	Gferi_06340	Gferi_16640	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
AOT69215.1	AOT71042.1	Gferi_06340	Gferi_16645	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.910
AOT69215.1	AOT71138.1	Gferi_06340	Gferi_17220	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOT69215.1	AOT71139.1	Gferi_06340	Gferi_17225	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.909
AOT69215.1	AOT72502.1	Gferi_06340	Gferi_24885	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.846
AOT69215.1	AOT72504.1	Gferi_06340	Gferi_24895	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
AOT69215.1	AOT72505.1	Gferi_06340	Gferi_24900	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.909
AOT69215.1	AOT73295.1	Gferi_06340	Gferi_24880	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.840
AOT69215.1	pdhA	Gferi_06340	Gferi_16630	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.970
AOT69761.1	AOT69215.1	Gferi_09290	Gferi_06340	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
AOT69761.1	AOT71040.1	Gferi_09290	Gferi_16635	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.984
AOT69761.1	AOT71041.1	Gferi_09290	Gferi_16640	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
AOT69761.1	AOT71042.1	Gferi_09290	Gferi_16645	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921
AOT69761.1	AOT71138.1	Gferi_09290	Gferi_17220	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.992
AOT69761.1	AOT71139.1	Gferi_09290	Gferi_17225	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.921
AOT69761.1	AOT72502.1	Gferi_09290	Gferi_24885	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.839
AOT69761.1	AOT72504.1	Gferi_09290	Gferi_24895	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.990
AOT69761.1	AOT72505.1	Gferi_09290	Gferi_24900	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.921