(6 nodes) acetyl-CoA biosynthetic process from pyruvate, and Dihydrolipoamide dehydrogenase network (Geosporobacter ferrireducens)

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	pdhA	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)
	AOT71040.1	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
	AOT71041.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
	AOT71042.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
	AOT72504.1	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
	AOT72505.1	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)

Your Current Organism:

Geosporobacter ferrireducens

NCBI taxonomy Id: 1424294
Other names: G. ferrireducens, Geosporobacter sp. IRF9, JCM 19987, KCTC 15395, strain IRF9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT71040.1	AOT71041.1	Gferi_16635	Gferi_16640	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOT71040.1	AOT71042.1	Gferi_16635	Gferi_16645	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOT71040.1	AOT72504.1	Gferi_16635	Gferi_24895	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AOT71040.1	AOT72505.1	Gferi_16635	Gferi_24900	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.985
AOT71040.1	pdhA	Gferi_16635	Gferi_16630	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.999
AOT71041.1	AOT71040.1	Gferi_16640	Gferi_16635	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOT71041.1	AOT71042.1	Gferi_16640	Gferi_16645	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOT71041.1	AOT72504.1	Gferi_16640	Gferi_24895	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
AOT71041.1	AOT72505.1	Gferi_16640	Gferi_24900	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
AOT71041.1	pdhA	Gferi_16640	Gferi_16630	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.998
AOT71042.1	AOT71040.1	Gferi_16645	Gferi_16635	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOT71042.1	AOT71041.1	Gferi_16645	Gferi_16640	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOT71042.1	AOT72504.1	Gferi_16645	Gferi_24895	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOT71042.1	AOT72505.1	Gferi_16645	Gferi_24900	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.909
AOT71042.1	pdhA	Gferi_16645	Gferi_16630	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.990
AOT72504.1	AOT71040.1	Gferi_24895	Gferi_16635	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
AOT72504.1	AOT71041.1	Gferi_24895	Gferi_16640	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
AOT72504.1	AOT71042.1	Gferi_24895	Gferi_16645	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
AOT72504.1	AOT72505.1	Gferi_24895	Gferi_24900	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOT72504.1	pdhA	Gferi_24895	Gferi_16630	PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).	0.994