(10 nodes) De novo IMP biosynthetic process network (Geosporobacter ferrireducens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	purD	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (419 aa)
	purH	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
	purN	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (222 aa)
	purM	Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
	purF	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (471 aa)
	purC	Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (232 aa)
	AOT73069.1	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
	AOT69887.1	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1260 aa)
	purE	5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (174 aa)
	purK	5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (392 aa)

Your Current Organism:

Geosporobacter ferrireducens

NCBI taxonomy Id: 1424294
Other names: G. ferrireducens, Geosporobacter sp. IRF9, JCM 19987, KCTC 15395, strain IRF9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT69887.1	AOT73069.1	Gferi_10025	Gferi_10020	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.906
AOT69887.1	purC	Gferi_10025	Gferi_10015	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.	0.997
AOT69887.1	purD	Gferi_10025	Gferi_09990	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family.	0.999
AOT69887.1	purE	Gferi_10025	Gferi_10060	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.996
AOT69887.1	purF	Gferi_10025	Gferi_10010	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.998
AOT69887.1	purH	Gferi_10025	Gferi_09995	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AOT69887.1	purK	Gferi_10025	Gferi_10065	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.997
AOT69887.1	purM	Gferi_10025	Gferi_10005	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOT69887.1	purN	Gferi_10025	Gferi_10000	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.	0.999
AOT73069.1	AOT69887.1	Gferi_10020	Gferi_10025	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.906
AOT73069.1	purC	Gferi_10020	Gferi_10015	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.	0.776
AOT73069.1	purD	Gferi_10020	Gferi_09990	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family.	0.751
AOT73069.1	purE	Gferi_10020	Gferi_10060	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).	0.678
AOT73069.1	purF	Gferi_10020	Gferi_10010	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.	0.710
AOT73069.1	purH	Gferi_10020	Gferi_09995	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.765
AOT73069.1	purK	Gferi_10020	Gferi_10065	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.637
AOT73069.1	purM	Gferi_10020	Gferi_10005	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.776
AOT73069.1	purN	Gferi_10020	Gferi_10000	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.	0.730
purC	AOT69887.1	Gferi_10015	Gferi_10025	Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.	Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
purC	AOT73069.1	Gferi_10015	Gferi_10020	Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family.	Guanine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.776