STRINGSTRING
queA queA AOT72884.1 AOT72884.1 AOT72843.1 AOT72843.1 AOT72842.1 AOT72842.1 AOT72841.1 AOT72841.1 AOT72840.1 AOT72840.1 hisA hisA AOT73307.1 AOT73307.1 AOT72639.1 AOT72639.1 AOT72628.1 AOT72628.1 nagB-4 nagB-4 AOT72577.1 AOT72577.1 AOT72571.1 AOT72571.1 mtnA mtnA tpiA tpiA hemL-2 hemL-2 AOT72383.1 AOT72383.1 AOT72349.1 AOT72349.1 AOT72345.1 AOT72345.1 AOT72340.1 AOT72340.1 AOT72204.1 AOT72204.1 AOT72174.1 AOT72174.1 pgi pgi kduI-2 kduI-2 menC-2 menC-2 menC menC AOT72008.1 AOT72008.1 AOT71966.1 AOT71966.1 AOT71842.1 AOT71842.1 AOT71701.1 AOT71701.1 nnrD nnrD gpmI gpmI AOT71584.1 AOT71584.1 AOT71582.1 AOT71582.1 AOT71455.1 AOT71455.1 glmM glmM AOT71379.1 AOT71379.1 AOT71321.1 AOT71321.1 AOT71294.1 AOT71294.1 AOT71293.1 AOT71293.1 AOT71235.1 AOT71235.1 truA-2 truA-2 AOT71099.1 AOT71099.1 AOT71081.1 AOT71081.1 AOT71080.1 AOT71080.1 AOT71059.1 AOT71059.1 AOT71023.1 AOT71023.1 truA truA nagB-3 nagB-3 AOT70832.1 AOT70832.1 topB topB kduI kduI AOT70676.1 AOT70676.1 AOT70650.1 AOT70650.1 AOT73132.1 AOT73132.1 AOT70577.1 AOT70577.1 AOT70568.1 AOT70568.1 AOT70492.1 AOT70492.1 aroK aroK pheA pheA AOT70485.1 AOT70485.1 AOT73111.1 AOT73111.1 gyrB gyrB gyrA gyrA AOT70382.1 AOT70382.1 AOT70357.1 AOT70357.1 AOT70356.1 AOT70356.1 nagB-2 nagB-2 nagB nagB AOT70168.1 AOT70168.1 AOT70165.1 AOT70165.1 AOT70164.1 AOT70164.1 AOT70131.1 AOT70131.1 AOT70130.1 AOT70130.1 AOT70088.1 AOT70088.1 AOT70084.1 AOT70084.1 AOT70055.1 AOT70055.1 AOT70054.1 AOT70054.1 groL groL AOT69903.1 AOT69903.1 hemL hemL AOT69899.1 AOT69899.1 purE purE AOT69868.1 AOT69868.1 tig tig AOT69744.1 AOT69744.1 AOT69589.1 AOT69589.1 AOT69327.1 AOT69327.1 AOT69300.1 AOT69300.1 trpF trpF murI murI AOT73009.1 AOT73009.1 AOT69030.1 AOT69030.1 AOT68888.1 AOT68888.1 AOT68786.1 AOT68786.1 AOT72981.1 AOT72981.1 AOT68695.1 AOT68695.1 AOT68694.1 AOT68694.1 uxaC uxaC AOT72958.1 AOT72958.1 AOT68427.1 AOT68427.1 dapF dapF AOT68411.1 AOT68411.1 AOT68333.1 AOT68333.1 topA topA truB truB deoB deoB AOT68119.1 AOT68119.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
queAtRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (341 aa)
AOT72884.1UDP-galactopyranose mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
AOT72843.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
AOT72842.1DNA mismatch repair protein MutL; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)
AOT72841.1LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (736 aa)
AOT72840.1Ornithine aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
AOT73307.1L-ribulose-5-phosphate 4-epimerase; Catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
AOT72639.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
AOT72628.1Fuculose phosphate aldolase; Catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
nagB-4Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (242 aa)
AOT72577.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
AOT72571.1AP endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
mtnAS-methyl-5-thioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (348 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
hemL-2Glutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AOT72383.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
AOT72349.1RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (322 aa)
AOT72345.116S rRNA pseudouridine(516) synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (240 aa)
AOT72340.1Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (172 aa)
AOT72204.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
AOT72174.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (447 aa)
kduI-25-dehydro-4-deoxy-D-glucuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (275 aa)
menC-2O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (369 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (370 aa)
AOT72008.1Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (212 aa)
AOT71966.1AroM family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
AOT71842.1Phenazine biosynthesis protein PhzF; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
AOT71701.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (391 aa)
nnrDHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (517 aa)
gpmIPhosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (519 aa)
AOT71584.1Hypothetical protein; Converts alpha-aldose to the beta-anomer. (345 aa)
AOT71582.1UDP-glucose 4-epimerase GalE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa)
AOT71455.1Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (448 aa)
AOT71379.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
AOT71321.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (281 aa)
AOT71294.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AOT71293.1Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AOT71235.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (451 aa)
truA-2tRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (244 aa)
AOT71099.1Amino-acid racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/glutamate racemases family. (230 aa)
AOT71081.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
AOT71080.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
AOT71059.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (330 aa)
AOT71023.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
truAtRNA pseudouridine(38-40) synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (245 aa)
nagB-3Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (244 aa)
AOT70832.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
topBDNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] (729 aa)
kduI5-dehydro-4-deoxy-D-glucuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (280 aa)
AOT70676.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (200 aa)
AOT70650.1Phenazine biosynthesis protein PhzF; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
AOT73132.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AOT70577.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AOT70568.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (200 aa)
AOT70492.1AP endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
aroKChorismate mutase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (265 aa)
pheAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AOT70485.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
AOT73111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (636 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (813 aa)
AOT70382.1Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
AOT70357.1Amino-acid racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AOT70356.1Phosphopentomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
nagB-2Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (241 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (240 aa)
AOT70168.1Lysine 2,3-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
AOT70165.1D-lysine 5,6-aminomutase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
AOT70164.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AOT70131.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
AOT70130.1UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (374 aa)
AOT70088.1Ribose 5-phosphate isomerase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AOT70084.1UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (373 aa)
AOT70055.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AOT70054.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
groLChaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (542 aa)
AOT69903.1Proline racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the proline racemase family. (334 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
AOT69899.1Nucleotidyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (822 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (174 aa)
AOT69868.1Dipeptide epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (425 aa)
AOT69744.1DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
AOT69589.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
AOT69327.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (188 aa)
AOT69300.1Beta-phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (200 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (274 aa)
AOT73009.1RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (281 aa)
AOT69030.1Lysine 2,3-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
AOT68888.1Hydantoin racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
AOT68786.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
AOT72981.1DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (707 aa)
AOT68695.1DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)
AOT68694.1Derived by automated computational analysis using gene prediction method: Protein Homology. (729 aa)
uxaCGlucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
AOT72958.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
AOT68427.1RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (309 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (277 aa)
AOT68411.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa)
AOT68333.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (378 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (691 aa)
truBtRNA pseudouridine(55) synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (297 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (389 aa)
AOT68119.1Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (235 aa)
Your Current Organism:
Geosporobacter ferrireducens
NCBI taxonomy Id: 1424294
Other names: G. ferrireducens, Geosporobacter sp. IRF9, JCM 19987, KCTC 15395, strain IRF9
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