STRINGSTRING
AOT72825.1 AOT72825.1 cmk cmk AOT68121.1 AOT68121.1 nusB nusB AOT72932.1 AOT72932.1 cinA cinA dut dut AOT68231.1 AOT68231.1 nusA nusA polC polC pyrH pyrH AOT68254.1 AOT68254.1 AOT68281.1 AOT68281.1 dinB dinB ackA ackA coaD coaD priA priA AOT68419.1 AOT68419.1 rpoZ rpoZ gmk gmk pyrR pyrR AOT68453.1 AOT68453.1 AOT68454.1 AOT68454.1 murA murA AOT68485.1 AOT68485.1 sigA sigA dnaG dnaG AOT68542.1 AOT68542.1 AOT68593.1 AOT68593.1 nadE nadE AOT68666.1 AOT68666.1 AOT68726.1 AOT68726.1 AOT68782.1 AOT68782.1 nadK nadK AOT68831.1 AOT68831.1 AOT68843.1 AOT68843.1 AOT68866.1 AOT68866.1 AOT68882.1 AOT68882.1 AOT68920.1 AOT68920.1 AOT73000.1 AOT73000.1 AOT68983.1 AOT68983.1 nadK-2 nadK-2 AOT69149.1 AOT69149.1 folD folD AOT69249.1 AOT69249.1 AOT69325.1 AOT69325.1 AOT69327.1 AOT69327.1 AOT69412.1 AOT69412.1 AOT69482.1 AOT69482.1 AOT73040.1 AOT73040.1 AOT69533.1 AOT69533.1 AOT69574.1 AOT69574.1 AOT69618.1 AOT69618.1 AOT69696.1 AOT69696.1 AOT69760.1 AOT69760.1 AOT69822.1 AOT69822.1 AOT69855.1 AOT69855.1 pyrD pyrD AOT69857.1 AOT69857.1 pyrC pyrC purD purD purH purH purN purN purM purM purF purF purC purC AOT69887.1 AOT69887.1 purE purE purK purK guaA guaA guaB guaB AOT69943.1 AOT69943.1 sigI sigI AOT69994.1 AOT69994.1 AOT70039.1 AOT70039.1 murA-2 murA-2 atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH udk udk atpF atpF atpE atpE atpE-2 atpE-2 atpB atpB upp upp tdk tdk rho rho atpD-2 atpD-2 atpB-2 atpB-2 atpA-2 atpA-2 AOT70111.1 AOT70111.1 AOT70113.1 AOT70113.1 AOT70125.1 AOT70125.1 AOT70131.1 AOT70131.1 pyrG pyrG AOT70236.1 AOT70236.1 AOT70288.1 AOT70288.1 tmk tmk dnaX dnaX AOT70313.1 AOT70313.1 AOT70375.1 AOT70375.1 carB carB carA carA AOT70394.1 AOT70394.1 serS serS AOT70410.1 AOT70410.1 AOT73107.1 AOT73107.1 AOT70460.1 AOT70460.1 AOT70532.1 AOT70532.1 purA purA murA-3 murA-3 AOT70569.1 AOT70569.1 Gferi_13925 Gferi_13925 AOT70574.1 AOT70574.1 AOT70626.1 AOT70626.1 AOT70636.1 AOT70636.1 AOT70642.1 AOT70642.1 AOT70671.1 AOT70671.1 AOT73144.1 AOT73144.1 AOT70777.1 AOT70777.1 AOT70929.1 AOT70929.1 AOT70949.1 AOT70949.1 xpt xpt pyrE pyrE pdhA pdhA AOT71041.1 AOT71041.1 glmU glmU prs prs AOT71084.1 AOT71084.1 AOT73176.1 AOT73176.1 coaX coaX AOT71093.1 AOT71093.1 AOT71137.1 AOT71137.1 AOT71138.1 AOT71138.1 thyX thyX AOT71150.1 AOT71150.1 nusG nusG rpoB rpoB rpoC rpoC adk adk rpoA rpoA AOT71229.1 AOT71229.1 AOT71273.1 AOT71273.1 nadD nadD AOT71284.1 AOT71284.1 AOT71338.1 AOT71338.1 AOT71360.1 AOT71360.1 pyrB pyrB pyrF pyrF pyrK pyrK pyrD-2 pyrD-2 ndk ndk dacA dacA AOT71427.1 AOT71427.1 AOT71433.1 AOT71433.1 AOT71445.1 AOT71445.1 AOT71446.1 AOT71446.1 AOT71532.1 AOT71532.1 AOT71614.1 AOT71614.1 AOT71618.1 AOT71618.1 queF queF AOT71677.1 AOT71677.1 AOT71782.1 AOT71782.1 AOT71840.1 AOT71840.1 Gferi_22215 Gferi_22215 rpoZ-2 rpoZ-2 AOT72114.1 AOT72114.1 AOT72197.1 AOT72197.1 AOT72244.1 AOT72244.1 AOT72247.1 AOT72247.1 AOT72870.1 AOT72870.1 AOT72252.1 AOT72252.1 AOT73279.1 AOT73279.1 Gferi_23930 Gferi_23930 AOT72360.1 AOT72360.1 AOT72423.1 AOT72423.1 AOT72456.1 AOT72456.1 AOT72458.1 AOT72458.1 AOT73295.1 AOT73295.1 AOT72503.1 AOT72503.1 AOT72504.1 AOT72504.1 AOT72726.1 AOT72726.1 polA polA coaE coaE AOT72729.1 AOT72729.1 dinB-2 dinB-2 nadD-2 nadD-2 AOT72774.1 AOT72774.1 selA selA AOT72805.1 AOT72805.1 queA queA tgt tgt apt apt
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AOT72825.1(p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (722 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AOT68121.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
nusBTranscription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (133 aa)
AOT72932.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (459 aa)
cinACompetence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (409 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
AOT68231.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (312 aa)
nusATranscription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (354 aa)
polCPolC-type DNA polymerase III; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1414 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa)
AOT68254.1RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (242 aa)
AOT68281.1EscN/YscN/HrcN family type III secretion system ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (420 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (825 aa)
AOT68419.1Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (206 aa)
pyrRBifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (180 aa)
AOT68453.1Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (257 aa)
AOT68454.1Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (249 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
AOT68485.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa)
sigARNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (372 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (615 aa)
AOT68542.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
AOT68593.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (468 aa)
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (251 aa)
AOT68666.1RNA polymerase sigma-F factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (256 aa)
AOT68726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
AOT68782.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
nadKHypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (277 aa)
AOT68831.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa)
AOT68843.14Fe-4S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
AOT68866.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (172 aa)
AOT68882.1Spore coat protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (288 aa)
AOT68920.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (177 aa)
AOT73000.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
AOT68983.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (60 aa)
nadK-2NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (269 aa)
AOT69149.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
AOT69249.1Cytidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1635 aa)
AOT69325.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (292 aa)
AOT69327.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (188 aa)
AOT69412.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
AOT69482.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
AOT73040.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
AOT69533.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
AOT69574.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
AOT69618.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa)
AOT69696.1Deoxyguanosine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AOT69760.1Uridine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
AOT69822.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (531 aa)
AOT69855.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
pyrDDihydroorotate dehydrogenase B catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (304 aa)
AOT69857.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (256 aa)
pyrCHypothetical protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (425 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (419 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (222 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (471 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (232 aa)
AOT69887.1Phosphoribosylformylglycinamidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1260 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (174 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (392 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (511 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (486 aa)
AOT69943.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
sigIRNA polymerase sigma-I factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; Belongs to the sigma-70 factor family. SigI subfamily. (244 aa)
AOT69994.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (192 aa)
AOT70039.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sigma-70 factor family. (191 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (134 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (465 aa)
atpGATP synthase F1 subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (504 aa)
atpHATP synthase F1 subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (180 aa)
udkUridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
atpFATP synthase F0 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (170 aa)
atpEATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (88 aa)
atpE-2ATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (184 aa)
atpBATP synthase F0 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (233 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (466 aa)
atpD-2ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. (207 aa)
atpB-2V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (457 aa)
atpA-2V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (589 aa)
AOT70111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (213 aa)
AOT70113.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AOT70125.1UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-glucuronate from UDP-glucose; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AOT70131.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (540 aa)
AOT70236.1Anaerobic sulfite reductase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AOT70288.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (207 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (548 aa)
AOT70313.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sigma-70 factor family. ECF subfamily. (208 aa)
AOT70375.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (178 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1072 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (359 aa)
AOT70394.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (160 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa)
AOT70410.1Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (303 aa)
AOT73107.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (257 aa)
AOT70460.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)
AOT70532.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (443 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)
murA-3UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
AOT70569.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (411 aa)
Gferi_13925IS110 family transposase; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AOT70574.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (388 aa)
AOT70626.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa)
AOT70636.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (181 aa)
AOT70642.1(Fe-S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
AOT70671.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)
AOT73144.1GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
AOT70777.1ACT domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0237 family. (89 aa)
AOT70929.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (194 aa)
AOT70949.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (211 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (362 aa)
AOT71041.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (460 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa)
AOT71084.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
AOT73176.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (257 aa)
AOT71093.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (787 aa)
AOT71137.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
AOT71138.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
thyXFAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (252 aa)
AOT71150.1RNA polymerase factor sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (214 aa)
nusGTranscription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (172 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1237 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1162 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (315 aa)
AOT71229.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
AOT71273.1Quinolinate phosphoribosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (211 aa)
AOT71284.11-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
AOT71338.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (259 aa)
AOT71360.1Aspartate carbamoyltransferase regulatory subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (309 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (314 aa)
pyrKHypothetical protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (258 aa)
pyrD-2Dihydroorotate dehydrogenase B catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (305 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (144 aa)
dacATIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (267 aa)
AOT71427.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (176 aa)
AOT71433.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sigma-70 factor family. ECF subfamily. (163 aa)
AOT71445.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (186 aa)
AOT71446.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
AOT71532.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AOT71614.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (178 aa)
AOT71618.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (108 aa)
queFNADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (167 aa)
AOT71677.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
AOT71782.1DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1156 aa)
AOT71840.1Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
Gferi_22215MFS transporter; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (146 aa)
rpoZ-2DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (68 aa)
AOT72114.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (74 aa)
AOT72197.1GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
AOT72244.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AOT72247.1DUF4406 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AOT72870.1Flagellar biosynthesis protein FliA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sigma-70 factor family. (158 aa)
AOT72252.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AOT73279.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
Gferi_23930Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (261 aa)
AOT72360.1tRNA epoxyqueuosine(34) reductase QueG; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
AOT72423.1RNA polymerase sigma-54 factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
AOT72456.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)
AOT72458.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
AOT73295.1Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
AOT72503.1ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (331 aa)
AOT72504.1PdhC; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
AOT72726.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (888 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)
AOT72729.1Nicotinate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
dinB-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (344 aa)
nadD-2Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (208 aa)
AOT72774.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (468 aa)
AOT72805.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (565 aa)
queAtRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (341 aa)
tgttRNA guanosine(34) transglycosylase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...] (372 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)
Your Current Organism:
Geosporobacter ferrireducens
NCBI taxonomy Id: 1424294
Other names: G. ferrireducens, Geosporobacter sp. IRF9, JCM 19987, KCTC 15395, strain IRF9
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