(47 nodes) Butanoate metabolism network (Geosporobacter ferrireducens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOT68111.1	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
	AOT68112.1	2-oxoglutarate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
	pflD	Formate C-acetyltransferase; Involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (762 aa)
	AOT69020.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (469 aa)
	AOT69071.1	Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
	AOT69074.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (88 aa)
	AOT69531.1	glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (387 aa)
	AOT69532.1	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
	AOT73040.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
	AOT69569.1	acetyl-CoA acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
	AOT69629.1	Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa)
	AOT69724.1	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
	AOT69725.1	2-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
	AOT69808.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	AOT69834.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
	AOT69919.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
	AOT73073.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
	AOT70095.1	succinyl-CoA--3-ketoacid-CoA transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
	AOT70096.1	Branched-chain amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
	AOT70097.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	AOT70203.1	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	AOT70207.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (138 aa)
	AOT70300.1	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
	porA	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
	AOT70302.1	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (102 aa)
	AOT70303.1	Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
	AOT70441.1	Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1174 aa)
	AOT70494.1	Acetohydroxyacid synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (600 aa)
	AOT73116.1	hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
	gabD	Succinate-semialdehyde dehydrogenase (NADP(+)); Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
	AOT70864.1	Butanediol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
	AOT70878.1	Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
	AOT70879.1	Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
	AOT70908.1	Acetaldehyde dehydrogenase (acetylating); Derived by automated computational analysis using gene prediction method: GeneMarkS+. (482 aa)
	Gferi_16685	Thioredoxin peroxidase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (259 aa)
	AOT71050.1	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	AOT71079.1	acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
	AOT71276.1	Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (289 aa)
	AOT73197.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (757 aa)
	buk	Butyrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family. (360 aa)
	AOT73208.1	Phosphate butyryltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
	buk-2	Butyrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family. (358 aa)
	AOT71399.1	3-methyl-2-oxobutanoate dehydrogenase subunit VorB; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
	AOT71400.1	2-oxoglutarate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	AOT71518.1	Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology. (578 aa)
	AOT72201.1	Formate C-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (741 aa)
	AOT72617.1	Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1173 aa)

Your Current Organism:

Geosporobacter ferrireducens

NCBI taxonomy Id: 1424294
Other names: G. ferrireducens, Geosporobacter sp. IRF9, JCM 19987, KCTC 15395, strain IRF9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOT68111.1	AOT68112.1	Gferi_00065	Gferi_00070	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoglutarate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AOT68111.1	AOT69071.1	Gferi_00065	Gferi_05560	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.677
AOT68111.1	AOT69074.1	Gferi_00065	Gferi_05575	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.662
AOT68111.1	AOT69531.1	Gferi_00065	Gferi_08050	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).	0.650
AOT68111.1	AOT69569.1	Gferi_00065	Gferi_08250	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.660
AOT68111.1	AOT69724.1	Gferi_00065	Gferi_09095	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOT68111.1	AOT69725.1	Gferi_00065	Gferi_09100	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.915
AOT68111.1	AOT69808.1	Gferi_00065	Gferi_09590	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.660
AOT68111.1	AOT69919.1	Gferi_00065	Gferi_10190	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.660
AOT68111.1	AOT70097.1	Gferi_00065	Gferi_11155	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.660
AOT68111.1	AOT70203.1	Gferi_00065	Gferi_11720	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.660
AOT68111.1	AOT70300.1	Gferi_00065	Gferi_12275	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.623
AOT68111.1	AOT70302.1	Gferi_00065	Gferi_12285	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.887
AOT68111.1	AOT70303.1	Gferi_00065	Gferi_12290	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.877
AOT68111.1	AOT70441.1	Gferi_00065	Gferi_13140	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOT68111.1	AOT70494.1	Gferi_00065	Gferi_13455	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetohydroxyacid synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.	0.677
AOT68111.1	AOT70878.1	Gferi_00065	Gferi_15720	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.677
AOT68111.1	AOT70879.1	Gferi_00065	Gferi_15725	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.662
AOT68111.1	AOT70908.1	Gferi_00065	Gferi_15880	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	Acetaldehyde dehydrogenase (acetylating); Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.903
AOT68111.1	AOT71079.1	Gferi_00065	Gferi_16865	2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.903