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mamP mamP mamO mamO mamN mamN mamM mamM mamL mamL
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Your Input:
mamPMagnetosome protein MamP, containing PDZ-like domain; Involved in redox-control of magnetite formation (By similarity). Oxidizes Fe(2+) at alkaline pH; successively forms ferrihydrite (Fe(3+)(2)O(3) 0.5 H(2)O) then magnetite (Fe(3)O(4)) from an Fe(2+) solution (By similarity); Belongs to the magnetosome MamP family. (270 aa)
mamOProbable membrane transporter protein MamO; Plays 2 roles; promotes magnetite nucleation/formation and activates the MamE protease (By similarity). Despite its near conservation of a protease-like sequence, this is probably not a protease (By similarity). Required in conjunction with MamP for proteolysis of at least MamE, itself and MamP (By similarity). May transport a solute that controls MamE's protease activity. May place individual iron atoms into the magnetite lattice (By similarity). One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamL [...] (632 aa)
mamNMagnetosome protein MamN, containing Divalent ion symporter domain; Plays a role in biomineralization; might regulate pH in the magnetosome; Belongs to the arsenite-antimonite (ArsB) efflux (TC 2.A.45) family. (437 aa)
mamMMagnetosome protein MamM, containing Cation efflux protein; Essential for magnetosome formation; required for stable accumulation of MamB. May nucleate iron crystal formation (Probable). Probably binds and transports iron. Binds divalent cations, possibly up to 3 Zn(2+) per dimer in vitro, probably iron in vivo (Probable). One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis. (318 aa)
mamLMagnetosome protein MamL; Involved in magnetite crystal maturation, but not in magnetosome vesicle tubulation or formation. One of 7 genes (mamLQBIEMO) able to induce magnetosome membrane biogenesis; coexpression of mamLQRBIEMO in a deletion of the 17 gene mamAB operon restores magnetosome vesicle formation but not magnetite biosynthesis. (78 aa)
Your Current Organism:
Magnetospirillum gryphiswaldense
NCBI taxonomy Id: 1430440
Other names: M. gryphiswaldense MSR-1 v2, Magnetospirillum gryphiswaldense MSR-1 v2, Magnetospirillum gryphiswaldense str. MSR-1 v2
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