STRINGSTRING
AKB26696.1 AKB26696.1 AKB23503.1 AKB23503.1 AKB23515.1 AKB23515.1 AKB23519.1 AKB23519.1 AKB23564.1 AKB23564.1 AKB23570.1 AKB23570.1 thyA thyA AKB23670.1 AKB23670.1 AKB23692.1 AKB23692.1 AKB23727.1 AKB23727.1 AKB23732.1 AKB23732.1 AKB23736.1 AKB23736.1 AKB23741.1 AKB23741.1 ogt ogt cbiT cbiT AKB23806.1 AKB23806.1 AKB23807.1 AKB23807.1 AKB23810.1 AKB23810.1 AKB23929.1 AKB23929.1 AKB23930.1 AKB23930.1 AKB23995.1 AKB23995.1 AKB24040.1 AKB24040.1 AKB24043.1 AKB24043.1 AKB24096.1 AKB24096.1 AKB24114.1 AKB24114.1 cdhE cdhE cdhE-2 cdhE-2 AKB24185.1 AKB24185.1 AKB24265.1 AKB24265.1 AKB24543.1 AKB24543.1 AKB24547.1 AKB24547.1 AKB24548.1 AKB24548.1 AKB24549.1 AKB24549.1 AKB24564.1 AKB24564.1 AKB24608.1 AKB24608.1 AKB24609.1 AKB24609.1 AKB24662.1 AKB24662.1 AKB24700.1 AKB24700.1 AKB24729.1 AKB24729.1 AKB24771.1 AKB24771.1 AKB24825.1 AKB24825.1 AKB24907.1 AKB24907.1 AKB24918.1 AKB24918.1 AKB24940.1 AKB24940.1 AKB26710.1 AKB26710.1 AKB24948.1 AKB24948.1 AKB24957.1 AKB24957.1 AKB24993.1 AKB24993.1 AKB25118.1 AKB25118.1 AKB25353.1 AKB25353.1 AKB25374.1 AKB25374.1 AKB25375.1 AKB25375.1 AKB25380.1 AKB25380.1 AKB25385.1 AKB25385.1 AKB25387.1 AKB25387.1 AKB25416.1 AKB25416.1 AKB25445.1 AKB25445.1 AKB25474.1 AKB25474.1 AKB25492.1 AKB25492.1 rsmA rsmA trmY trmY trm1 trm1 AKB25570.1 AKB25570.1 AKB25573.1 AKB25573.1 AKB25624.1 AKB25624.1 dphB dphB AKB25655.1 AKB25655.1 AKB25717.1 AKB25717.1 AKB25863.1 AKB25863.1 AKB25885.1 AKB25885.1 AKB25886.1 AKB25886.1 AKB26018.1 AKB26018.1 AKB26019.1 AKB26019.1 AKB26020.1 AKB26020.1 AKB26107.1 AKB26107.1 AKB26118.1 AKB26118.1 AKB26135.1 AKB26135.1 AKB26155.1 AKB26155.1 AKB26177.1 AKB26177.1 AKB26209.1 AKB26209.1 AKB26271.1 AKB26271.1 pcm pcm AKB26373.1 AKB26373.1 AKB26376.1 AKB26376.1 AKB26379.1 AKB26379.1 AKB26380.1 AKB26380.1 cbiD cbiD AKB26391.1 AKB26391.1 AKB26395.1 AKB26395.1 AKB26432.1 AKB26432.1 flpA flpA AKB26444.1 AKB26444.1 mtrE mtrE mtrD mtrD mtrC mtrC mtrB mtrB mtrA mtrA mtrF mtrF mtrG mtrG mtrH mtrH AKB26512.1 AKB26512.1 AKB26518.1 AKB26518.1 AKB26547.1 AKB26547.1 AKB26556.1 AKB26556.1 AKB26584.1 AKB26584.1 AKB26595.1 AKB26595.1 AKB26597.1 AKB26597.1 AKB26673.1 AKB26673.1 AKB26674.1 AKB26674.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB26696.1Methyltransferase. (261 aa)
AKB23503.1Fe-S OXIDOREDUCTASE. (705 aa)
AKB23515.1C-20 methyltransferase BchU. (349 aa)
AKB23519.1Hypothetical protein. (345 aa)
AKB23564.1Methyl coenzyme M reductase associated protein / Fe-S oxidoreductase, related to NifB/MoaA family. (411 aa)
AKB23570.1RNA methyltransferase related protein. (326 aa)
thyAThymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. (217 aa)
AKB23670.1D-arabino-3-hexulose 6-phosphate formaldehyde lyase; Hypothetical protein with distant similarity to Ribonuclease E inhibitor RraA (former MenG). (413 aa)
AKB23692.1Thymidylate synthase. (225 aa)
AKB23727.1Methanol:corrinoid methyltransferase. (461 aa)
AKB23732.1Dimethylsulfide:corrinoid methyltransferase. (631 aa)
AKB23736.1Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (339 aa)
AKB23741.1Putative methyltransferase YodH. (285 aa)
ogtMethylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (154 aa)
cbiTCobalt-precorrin-6y C15-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. (181 aa)
AKB23806.1Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (202 aa)
AKB23807.1Cobalt-precorrin-4 C11-methyltransferase. (242 aa)
AKB23810.1Cobalt-precorrin-3b C17-methyltransferase. (266 aa)
AKB23929.1Hypothetical protein. (285 aa)
AKB23930.1Hypothetical protein. (143 aa)
AKB23995.1Hypothetical protein. (241 aa)
AKB24040.15-methyltetrahydrofolate--homocysteine methyltransferase. (221 aa)
AKB24043.15-methyltetrahydrofolate--homocysteine methyltransferase. (213 aa)
AKB24096.1Hypothetical protein. (280 aa)
AKB24114.1Hypothetical protein. (294 aa)
cdhE5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (469 aa)
cdhE-25-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (469 aa)
AKB24185.1tRNA (adenine57/58-N1)-methyltransferase. (249 aa)
AKB24265.1Phosphatidylethanolamine N-methyltransferase. (198 aa)
AKB24543.1Hypothetical protein. (74 aa)
AKB24547.1Tetrahydromethanopterin S-methyltransferase subunit H. (310 aa)
AKB24548.1Tetrahydromethanopterin S-methyltransferase subunit A 1. (196 aa)
AKB24549.1N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit X. (284 aa)
AKB24564.1Thymidylate synthase. (271 aa)
AKB24608.1Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (339 aa)
AKB24609.1Methanol:corrinoid methyltransferase. (460 aa)
AKB24662.1Type I restriction-modification system, DNA-methyltransferase subunit M. (517 aa)
AKB24700.1tRNA cytosine methylase Pos56. (143 aa)
AKB24729.1Arsenite S-adenosylmethyltransferase. (254 aa)
AKB24771.1Type I restriction-modification system, DNA-methyltransferase subunit M. (504 aa)
AKB24825.1Type I restriction-modification system, DNA-methyltransferase subunit M. (576 aa)
AKB24907.1Hypothetical protein. (345 aa)
AKB24918.1Putative methyltransferase. (283 aa)
AKB24940.1Tungsten-containing formylmethanofuran dehydrogenase 2 subunit G. (154 aa)
AKB26710.1Chemotaxis protein methyltransferase CheR. (302 aa)
AKB24948.1Ubiquinone/menaquinone biosynthesis methyltransferase. (224 aa)
AKB24957.1Putative DNA methylase. (834 aa)
AKB24993.1Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (458 aa)
AKB25118.1Hypothetical protein. (155 aa)
AKB25353.1Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (467 aa)
AKB25374.1Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (336 aa)
AKB25375.15-methyltetrahydrofolate--homocysteine methyltransferase. (217 aa)
AKB25380.15-methyltetrahydrofolate--homocysteine methyltransferase. (216 aa)
AKB25385.1Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (335 aa)
AKB25387.1Dimethylsulfide:corrinoid methyltransferase. (216 aa)
AKB25416.1Methyltransferase. (229 aa)
AKB25445.1Type I restriction-modification system, DNA-methyltransferase subunit M. (483 aa)
AKB25474.1O-methyltransferase. (373 aa)
AKB25492.1Putative methyltransferase. (202 aa)
rsmAPutative ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (273 aa)
trmYProtein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (213 aa)
trm1tRNA N2,N2-dimethyl(Guanine26-N2)-methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (386 aa)
AKB25570.1N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A. (184 aa)
AKB25573.1SAM-dependent methyltransferase. (223 aa)
AKB25624.1Hypothetical protein. (281 aa)
dphBDiphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. (266 aa)
AKB25655.1Hypothetical protein. (303 aa)
AKB25717.1Uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. (255 aa)
AKB25863.1Hypothetical protein. (388 aa)
AKB25885.1Methylcobamide:CoM methyltransferase MtaA. (345 aa)
AKB25886.1Methyltransferase. (314 aa)
AKB26018.1Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (467 aa)
AKB26019.1Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family. (495 aa)
AKB26020.1Trimethylamine methyltransferase corrinoid protein. (217 aa)
AKB26107.1Methylated-DNA--protein-cysteine methyltransferase. (227 aa)
AKB26118.1Hypothetical protein. (352 aa)
AKB26135.1Hypothetical protein. (198 aa)
AKB26155.1Hypothetical protein. (243 aa)
AKB26177.1Ribosomal protein L11 methyltransferase. (196 aa)
AKB26209.1tRNA:Cm32/Um32 methyltransferase. (249 aa)
AKB26271.1Type I restriction-modification system, DNA-methyltransferase subunit M. (64 aa)
pcmProtein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (242 aa)
AKB26373.1LysM protein. (225 aa)
AKB26376.1Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (467 aa)
AKB26379.1Trimethylamine methyltransferase corrinoid protein. (215 aa)
AKB26380.1Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family. (497 aa)
cbiDCobalt-precorrin-6 synthase, anaerobic; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (339 aa)
AKB26391.1Cobalt-precorrin-6y C5-methyltransferase. (195 aa)
AKB26395.1Methanol:corrinoid methyltransferase. (461 aa)
AKB26432.1Hypothetical protein. (150 aa)
flpAFibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (229 aa)
AKB26444.1rRNA biogenesis protein Nop5/Nop56. (338 aa)
mtrEN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (305 aa)
mtrDN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (240 aa)
mtrCN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (267 aa)
mtrBN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (108 aa)
mtrAN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (240 aa)
mtrFN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit F; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (72 aa)
mtrGN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (72 aa)
mtrHN5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA. (315 aa)
AKB26512.1(dimethylallyl)adenosine tRNA methylthiotransferase. (387 aa)
AKB26518.1Dimethylsulfide:corrinoid methyltransferase. (213 aa)
AKB26547.1tRNA-(G10-N2) dimethyltransferase. (346 aa)
AKB26556.1Hypothetical protein. (346 aa)
AKB26584.1Fe-S oxidoreductase. (327 aa)
AKB26595.1Methylcobalamin:coenzyme M methyltransferase, methylamine-specific. (339 aa)
AKB26597.1Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (458 aa)
AKB26673.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (344 aa)
AKB26674.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (347 aa)
Your Current Organism:
Methanosarcina sp. MTP4
NCBI taxonomy Id: 1434100
Other names: M. sp. MTP4
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