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| | guaAB | GMP synthase (glutamine-hydrolyzing), ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP. (304 aa) |
| | AKB23623.1 | Methionyl-tRNA formyltransferase. (235 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory chain (PyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa) |
| | pyrB | Aspartate carbamoyltransferase. (298 aa) |
| | tmk | Thymidylate kinase. (207 aa) |
| | AKB23701.1 | Geranylgeranyl/isoprenyl reductase. (385 aa) |
| | AKB23716.1 | 7,8 dihydropteroate synthase (methanopterin). (220 aa) |
| | AKB23756.1 | Molybdopterin biosynthesis protein MoeA; Periplasmic molybdate-binding domain. (663 aa) |
| | thiC | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (428 aa) |
| | AKB23890.1 | (S)-3-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (247 aa) |
| | AKB23892.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa) |
| | AKB23913.1 | GDP-mannose mannosyl hydrolase. (145 aa) |
| | AKB23935.1 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. (538 aa) |
| | AKB23948.1 | Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (349 aa) |
| | AKB23951.1 | Adenylate cyclase. (177 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase, synthetase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (715 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (237 aa) |
| | AKB23991.1 | Molybdopterin converting factor small subunit. (97 aa) |
| | AKB23992.1 | Molybdopterin biosynthesis MoeA protein. (397 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (424 aa) |
| | atpE | V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (183 aa) |
| | atpC | V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (357 aa) |
| | atpF | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (101 aa) |
| | atpA | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (578 aa) |
| | atpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (460 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (208 aa) |
| | AKB24069.1 | Thiamine monophosphate kinase. (326 aa) |
| | thiE | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (215 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (261 aa) |
| | AKB24115.1 | Geranylgeranyl diphosphate reductase. (396 aa) |
| | AKB24183.1 | Putative electron-transfer protein. (281 aa) |
| | AKB24207.1 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase. (191 aa) |
| | AKB24217.1 | Nicotinamide-nucleotide adenylyltransferase, NadM family. (154 aa) |
| | AKB24218.1 | AMP/CMP kinase AK6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (197 aa) |
| | uppS | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (312 aa) |
| | AKB24231.1 | NAD synthetase. (332 aa) |
| | thiI | tRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (438 aa) |
| | AKB24287.1 | Phosphopantothenoylcysteine synthetase. (525 aa) |
| | AKB24288.1 | Pantoate kinase, archaeal. (301 aa) |
| | AKB24290.1 | Phosphopantothenate synthetase, archaeal. (253 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (141 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (283 aa) |
| | egsA | Glycerol-1-phosphate dehydrogenase [NAD(P)]; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (354 aa) |
| | AKB24378.1 | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase. (387 aa) |
| | AKB24383.1 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (181 aa) |
| | AKB24423.1 | Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (407 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (143 aa) |
| | pdxT | Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (203 aa) |
| | pdxS | Pyridoxine biosynthesis glutamine amidotransferase, synthase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (298 aa) |
| | AKB24534.1 | Metallo-beta-lactamase family protein. (474 aa) |
| | ribL | FMN adenylyltransferase, type 3 archaeal; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (139 aa) |
| | thi4 | Thiazole biosynthetic enzyme Thi4; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (260 aa) |
| | AKB24595.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (313 aa) |
| | thiC-2 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (427 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (436 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (186 aa) |
| | carS | Phosphatidate cytidylyltransferase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (175 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa) |
| | AKB24717.1 | Xanthine-guanine phosphoribosyltransferase. (242 aa) |
| | AKB24760.1 | Putative NTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (174 aa) |
| | nadK | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (274 aa) |
| | AKB24839.1 | Molybdopterin-guanine dinucleotide biosynthesis protein MobB. (277 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (221 aa) |
| | AKB24842.1 | Molybdopterin-guanine dinucleotide biosynthesis protein. (96 aa) |
| | AKB24855.1 | Asparagine synthetase (glutamine-hydrolyzing). (507 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (83 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (232 aa) |
| | AKB24861.1 | 7,8 dihydropteroate synthase (methanopterin). (280 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1067 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (369 aa) |
| | AKB24978.1 | Digeranylgeranylglycerophospholipid reductase. (432 aa) |
| | AKB25074.1 | Inositol-1-phosphate synthase. (385 aa) |
| | AKB25109.1 | 7,8 dihydropteroate synthase (methanopterin). (218 aa) |
| | AKB25228.1 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (556 aa) |
| | AKB25230.1 | Ketoisovalerate oxidoreductase subunit VorC. (82 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (386 aa) |
| | mptE | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (216 aa) |
| | AKB25398.1 | CDP-diacylglycerol--serine O-phosphatidyltransferase. (218 aa) |
| | AKB25406.1 | Ubiquitin-like small archaeal modifier protein SAMP1. (94 aa) |
| | AKB25414.1 | Indolepyruvate oxidoreductase subunit IorB. (197 aa) |
| | AKB25545.1 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase. (295 aa) |
| | AKB25596.1 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase. (283 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (131 aa) |
| | AKB25689.1 | Transcriptional regulator, MerR family. (192 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (471 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa) |
| | AKB25830.1 | Phosphoribosylglycinamide formyltransferase. (202 aa) |
| | nadE | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (256 aa) |
| | coaD | Phosphopantetheine adenylyltransferase, type II eukaryotic; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (154 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa) |
| | cmk | Cytidylate kinase. (180 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | AKB25979.1 | Indolepyruvate oxidoreductase subunit IorB. (213 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (221 aa) |
| | AKB25994.1 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (278 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (305 aa) |
| | nadX | L-Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (271 aa) |
| | AKB25997.1 | Quinolinate phosphoribosyltransferase (decarboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (282 aa) |
| | AKB26031.1 | Orotate phosphoribosyltransferase related protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (198 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (467 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (232 aa) |
| | AKB26120.1 | Digeranylgeranylglyceryl phosphate synthase. (297 aa) |
| | AKB26153.1 | Hypothetical protein. (80 aa) |
| | hpt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (189 aa) |
| | AKB26197.1 | Indolepyruvate oxidoreductase subunit IorA. (223 aa) |
| | AKB26201.1 | Geranylgeranyl diphosphate reductase. (374 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (301 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (259 aa) |
| | pyrD | Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (301 aa) |
| | ribK | DNA-binding HTH domain in riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (228 aa) |
| | AKB26383.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (226 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (160 aa) |
| | AKB26422.1 | Circadian phase modifier. (280 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (233 aa) |
| | AKB26460.1 | Molybdenum transport system protein ModD; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (265 aa) |
| | AKB26498.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (202 aa) |
| | fdhD | Formate dehydrogenase chain D; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. (254 aa) |
| | purP | Phosphoribosylaminoimidazolecarboxamide formyltransferase(alternate form); Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (356 aa) |
| | AKB26563.1 | Molybdenum cofactor biosynthesis protein MoaB. (179 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (333 aa) |
| | mptD | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). (123 aa) |
| | AKB26623.1 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (231 aa) |
| | asd | Phosphatidylserine decarboxylase; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily. (208 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (351 aa) |
| | AKB26656.1 | Inositol-1-phosphate synthase. (367 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (382 aa) |
| | AKB26686.1 | Pyruvate:ferredoxin oxidoreductase, gamma subunit. (182 aa) |
| | AKB26687.1 | Pyruvate:ferredoxin oxidoreductase, delta subunit. (86 aa) |
| | AKB26688.1 | Pyruvate:ferredoxin oxidoreductase, alpha subunit. (403 aa) |
| | AKB26689.1 | Pyruvate:ferredoxin oxidoreductase, beta subunit. (296 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (393 aa) |
| | guaAA | GMP synthase (glutamine-hydrolyzing), amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. (193 aa) |
| | AKB23535.1 | Xanthine-guanine phosphoribosyltransferase. (243 aa) |
| | thyA | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. (217 aa) |
| | mptA | GTP cyclohydrolase I type 2; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (319 aa) |
