STRINGSTRING
AKB24293.1 AKB24293.1 AKB23525.1 AKB23525.1 aroE aroE AKB23597.1 AKB23597.1 AKB23600.1 AKB23600.1 AKB23603.1 AKB23603.1 AKB23604.1 AKB23604.1 AKB23618.1 AKB23618.1 AKB23619.1 AKB23619.1 dapB dapB AKB23681.1 AKB23681.1 AKB23682.1 AKB23682.1 AKB23683.1 AKB23683.1 AKB23835.1 AKB23835.1 AKB23921.1 AKB23921.1 proC proC ilvC ilvC AKB24232.1 AKB24232.1 AKB24240.1 AKB24240.1 AKB24253.1 AKB24253.1 AKB24336.1 AKB24336.1 AKB24338.1 AKB24338.1 AKB24421.1 AKB24421.1 AKB24531.1 AKB24531.1 AKB24595.1 AKB24595.1 AKB24614.1 AKB24614.1 ala ala AKB24701.1 AKB24701.1 AKB24719.1 AKB24719.1 gap gap AKB24976.1 AKB24976.1 AKB25074.1 AKB25074.1 AKB25205.1 AKB25205.1 AKB25206.1 AKB25206.1 AKB25292.1 AKB25292.1 AKB25332.1 AKB25332.1 AKB25333.1 AKB25333.1 AKB25418.1 AKB25418.1 AKB25700.1 AKB25700.1 AKB25786.1 AKB25786.1 AKB25787.1 AKB25787.1 folD folD argC argC nadX nadX AKB26092.1 AKB26092.1 AKB26343.1 AKB26343.1 hemA hemA AKB26356.1 AKB26356.1 AKB26419.1 AKB26419.1 AKB26656.1 AKB26656.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB24293.1Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. (411 aa)
AKB23525.1Prephenate and/or arogenate dehydrogenase (unknown specificity). (475 aa)
aroEShikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (279 aa)
AKB23597.1UDP-glucose 4-epimerase. (298 aa)
AKB23600.1UDP-glucose 4-epimerase. (322 aa)
AKB23603.1Myo-inositol 2-dehydrogenase. (310 aa)
AKB23604.1UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (476 aa)
AKB23618.1dTDP-glucose 4,6-dehydratase. (318 aa)
AKB23619.1dTDP-4-dehydrorhamnose reductase. (269 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa)
AKB23681.1UDP-glucose dehydrogenase. (427 aa)
AKB23682.1UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (498 aa)
AKB23683.1Myo-inositol 2-dehydrogenase. (311 aa)
AKB23835.18-hydroxy-5-deazaflavin:NADPH oxidoreductase. (235 aa)
AKB23921.1Glutathione-regulated potassium-efflux system protein KefC. (663 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (335 aa)
AKB24232.13-oxoacyl-[acyl-carrier protein] reductase. (246 aa)
AKB24240.1UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (439 aa)
AKB24253.1Homoserine dehydrogenase. (332 aa)
AKB24336.1UDP-glucose 4-epimerase. (335 aa)
AKB24338.1Kef-type K+ transport systems (NAD-binding component fused to domain related to exopolyphosphatase). (488 aa)
AKB24421.1Trk system potassium uptake protein TrkA. (448 aa)
AKB24531.1Trk system potassium uptake protein TrkA. (216 aa)
AKB24595.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (313 aa)
AKB24614.1Glutathione-regulated potassium-efflux system protein KefB. (618 aa)
alaOrnithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily. (326 aa)
AKB24701.1Acetyl-CoA synthetase (ADP-forming) alpha chain. (458 aa)
AKB24719.1Glutathione-regulated potassium-efflux system protein KefC. (686 aa)
gapNAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (335 aa)
AKB24976.1NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)
AKB25074.1Inositol-1-phosphate synthase. (385 aa)
AKB25205.13-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (236 aa)
AKB25206.13-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa)
AKB25292.1Hypothetical protein. (145 aa)
AKB25332.1Potassium channel protein. (347 aa)
AKB25333.1Potassium channel protein. (225 aa)
AKB25418.1NAD-dependent malic enzyme. (416 aa)
AKB25700.1Trk system potassium uptake protein TrkA. (612 aa)
AKB25786.1Acetyl-CoA synthetase (ADP-forming) alpha chain. (455 aa)
AKB25787.1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (377 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (336 aa)
nadXL-Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (271 aa)
AKB26092.1Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (307 aa)
AKB26343.1D-3-phosphoglycerate dehydrogenase. (523 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (428 aa)
AKB26356.1Siroheme synthase; Precorrin-2 oxidase; Sirohydrochlorin ferrochelatase. (225 aa)
AKB26419.1Aspartate-semialdehyde dehydrogenase. (342 aa)
AKB26656.1Inositol-1-phosphate synthase. (367 aa)
Your Current Organism:
Methanosarcina sp. MTP4
NCBI taxonomy Id: 1434100
Other names: M. sp. MTP4
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