STRINGSTRING
AKB16893.1 AKB16893.1 mptA mptA AKB17031.1 AKB17031.1 AKB17226.1 AKB17226.1 AKB17227.1 AKB17227.1 AKB17228.1 AKB17228.1 AKB17229.1 AKB17229.1 AKB17230.1 AKB17230.1 AKB17390.1 AKB17390.1 AKB17467.1 AKB17467.1 AKB17681.1 AKB17681.1 uppS uppS AKB17902.1 AKB17902.1 carS carS AKB18277.1 AKB18277.1 AKB18485.1 AKB18485.1 AKB18486.1 AKB18486.1 AKB18716.1 AKB18716.1 AKB19020.1 AKB19020.1 AKB19130.1 AKB19130.1 AKB19162.1 AKB19162.1 fni fni AKB19166.1 AKB19166.1 mvk mvk AKB19555.1 AKB19555.1 AKB20035.1 AKB20035.1 AKB20036.1 AKB20036.1 AKB20063.1 AKB20063.1 AKB20107.1 AKB20107.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB16893.1Fe-S OXIDOREDUCTASE. (710 aa)
mptAGTP cyclohydrolase I type 2; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (318 aa)
AKB17031.1(dimethylallyl)adenosine tRNA methylthiotransferase. (373 aa)
AKB17226.1Adenylate cyclase. (179 aa)
AKB17227.1Conserved protein associated with acetyl-CoA C-acyltransferase. (132 aa)
AKB17228.1Beta-ketoacyl synthase/thiolase. (390 aa)
AKB17229.1Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (349 aa)
AKB17230.1Hypothetical protein. (246 aa)
AKB17390.1Undecaprenyl diphosphate synthase. (224 aa)
AKB17467.1Geranylfarnesyl diphosphate synthetase; Belongs to the FPP/GGPP synthase family. (285 aa)
AKB17681.1Geranylgeranyl diphosphate reductase. (427 aa)
uppSUndecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (313 aa)
AKB17902.1Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (418 aa)
carSPhosphatidate cytidylyltransferase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (175 aa)
AKB18277.1Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (407 aa)
AKB18485.1Hypothetical protein. (107 aa)
AKB18486.1Hypothetical protein. (109 aa)
AKB18716.1Digeranylgeranylglycerophospholipid reductase. (421 aa)
AKB19020.1Benzodiazepine receptor TspO. (168 aa)
AKB19130.1(S)-3-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (247 aa)
AKB19162.1Geranylfarnesyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (321 aa)
fniIsopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (365 aa)
AKB19166.1Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (260 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (301 aa)
AKB19555.1(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (293 aa)
AKB20035.1Ferredoxin. (42 aa)
AKB20036.1Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (409 aa)
AKB20063.1Hypothetical protein. (246 aa)
AKB20107.1MutT protein. (173 aa)
Your Current Organism:
Methanosarcina sp. WWM596
NCBI taxonomy Id: 1434103
Other names: M. sp. WWM596
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