STRINGSTRING
AKB16897.1 AKB16897.1 fae-hps fae-hps tpiA tpiA AKB16915.1 AKB16915.1 aroE aroE aroD aroD aroB aroB aroA aroA guaAA guaAA aroA-2 aroA-2 thyA thyA argB argB AKB16999.1 AKB16999.1 leuD leuD hisG hisG hisA hisA hisB hisB AKB17028.1 AKB17028.1 AKB17036.1 AKB17036.1 AKB17037.1 AKB17037.1 pyrH pyrH AKB17155.1 AKB17155.1 aroA-3 aroA-3 dut dut purL purL AKB17248.1 AKB17248.1 gpmI gpmI AKB17297.1 AKB17297.1 AKB17298.1 AKB17298.1 AKB17299.1 AKB17299.1 AKB17300.1 AKB17300.1 hpt hpt mfnB mfnB tmk tmk AKB17368.1 AKB17368.1 proA proA proB proB proC proC purA purA purF purF trpB trpB hisD hisD AKB17512.1 AKB17512.1 folD folD glyA glyA AKB17521.1 AKB17521.1 AKB17610.1 AKB17610.1 AKB17684.1 AKB17684.1 AKB17685.1 AKB17685.1 cimA cimA AKB17724.1 AKB17724.1 AKB17725.1 AKB17725.1 ilvC ilvC AKB17730.1 AKB17730.1 AKB17731.1 AKB17731.1 AKB17738.1 AKB17738.1 hacB hacB AKB17751.1 AKB17751.1 AKB17752.1 AKB17752.1 purC purC AKB17810.1 AKB17810.1 AKB17825.1 AKB17825.1 AKB17837.1 AKB17837.1 leuC leuC AKB17899.1 AKB17899.1 AKB17900.1 AKB17900.1 AKB17961.1 AKB17961.1 purD purD pyrE pyrE AKB17971.1 AKB17971.1 AKB17972.1 AKB17972.1 eno eno ilvD ilvD AKB18117.1 AKB18117.1 ndk ndk carA carA carB carB argG argG AKB18467.1 AKB18467.1 AKB18585.1 AKB18585.1 purQ purQ purS purS AKB18623.1 AKB18623.1 AKB18643.1 AKB18643.1 gap gap trpC trpC trpB-2 trpB-2 trpA trpA trpD trpD trpF trpF trpE trpE AKB18742.1 AKB18742.1 AKB18747.1 AKB18747.1 guaAB guaAB AKB18782.1 AKB18782.1 pyrB pyrB pyrI pyrI dapB dapB dapA dapA ilvE ilvE AKB18923.1 AKB18923.1 AKB18957.1 AKB18957.1 AKB18958.1 AKB18958.1 AKB19093.1 AKB19093.1 AKB19128.1 AKB19128.1 AKB19161.1 AKB19161.1 AKB19175.1 AKB19175.1 pyrK pyrK pyrD pyrD aroC aroC hisF hisF lysA lysA AKB19311.1 AKB19311.1 AKB19313.1 AKB19313.1 pyrC pyrC hisI hisI hisH hisH AKB19514.1 AKB19514.1 AKB19517.1 AKB19517.1 katG katG pyrF pyrF AKB19565.1 AKB19565.1 pgk pgk argC argC argJ argJ pfkC pfkC AKB19596.1 AKB19596.1 AKB19636.1 AKB19636.1 AKB19651.1 AKB19651.1 argH argH AKB19692.1 AKB19692.1 AKB19704.1 AKB19704.1 AKB19791.1 AKB19791.1 AKB19793.1 AKB19793.1 AKB19794.1 AKB19794.1 aroK aroK AKB19800.1 AKB19800.1 AKB19801.1 AKB19801.1 hisE hisE leuC-2 leuC-2 gpmA gpmA pyrG pyrG AKB19906.1 AKB19906.1 AKB19909.1 AKB19909.1 AKB19945.1 AKB19945.1 AKB19965.1 AKB19965.1 AKB19997.1 AKB19997.1 AKB19998.1 AKB19998.1 AKB20157.1 AKB20157.1 apgM apgM AKB20162.1 AKB20162.1 purM purM argD argD hisC hisC surE surE AKB20243.1 AKB20243.1 AKB20244.1 AKB20244.1 AKB20245.1 AKB20245.1 AKB20246.1 AKB20246.1
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AKB16897.12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (512 aa)
fae-hpsFormaldehyde activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (392 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa)
AKB16915.1Prephenate and/or arogenate dehydrogenase (unknown specificity). (476 aa)
aroEShikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa)
aroD3-dehydroquinate dehydratase I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (246 aa)
aroB3,7-dideoxy-D-threo-hepto-2, 6-diulosonate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (380 aa)
aroA2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (265 aa)
guaAAGMP synthase (glutamine-hydrolyzing), amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. (189 aa)
aroA-25-Enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (430 aa)
thyAThymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. (217 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
AKB16999.13-isopropylmalate dehydrogenase. (375 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (162 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (289 aa)
hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (245 aa)
hisBImidazoleglycerol-phosphate dehydratase. (191 aa)
AKB17028.1GCN5-related N-acetyltransferase. (150 aa)
AKB17036.1Citrate synthase (si). (355 aa)
AKB17037.1Aconitate hydratase. (935 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (233 aa)
AKB17155.1Aspartate-semialdehyde dehydrogenase. (342 aa)
aroA-32-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (258 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (171 aa)
purLPhosphoribosylformylglycinamidine synthase, synthetase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (715 aa)
AKB17248.1IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. (538 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (515 aa)
AKB17297.1Pyruvate carboxyl transferase subunit B. (570 aa)
AKB17298.1Pyruvate carboxyl transferase subunit A. (493 aa)
AKB17299.1Biotin operon repressor; Biotin-protein ligase. (325 aa)
AKB17300.1Hypothetical protein. (206 aa)
hptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (189 aa)
mfnBDuf556 family protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (234 aa)
tmkThymidylate kinase. (205 aa)
AKB17368.1Phosphoserine phosphatase. (235 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (447 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (344 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (424 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (485 aa)
trpBTryptophan synthase beta chain 1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (432 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
AKB17512.1Coenzyme F420:L-glutamate ligase. (264 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
glyASerine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
AKB17521.1Phosphoribosylglycinamide formyltransferase. (202 aa)
AKB17610.1Methionyl-tRNA formyltransferase. (308 aa)
AKB17684.1Pyruvate kinase; Belongs to the pyruvate kinase family. (500 aa)
AKB17685.1Fructose-bisphosphate aldolase/6-deoxy-5-ketofructose 1-phosphate synthase. (307 aa)
cimA(R)-citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family. (483 aa)
AKB17724.1Acetolactate synthase large subunit. (564 aa)
AKB17725.1Acetolactate synthase small subunit. (161 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (335 aa)
AKB17730.1Glutamate synthase [NADPH] small chain. (469 aa)
AKB17731.1Putative electron-transfer protein. (281 aa)
AKB17738.1Phosphocholine cytidylyltransferase; Aspartate aminotransferase. (600 aa)
hacBCoenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] (165 aa)
AKB17751.1Coenzyme B synthesis from 2-oxoglutarate: steps 5, 9, and 13. (331 aa)
AKB17752.1Metal-dependent hydrolase. (217 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (237 aa)
AKB17810.1Alpha-acetolactate decarboxylase. (288 aa)
AKB17825.1Acetyl-CoA synthetase (ADP-forming) alpha chain. (476 aa)
AKB17837.1Prephenate dehydratase. (332 aa)
leuCCoenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (413 aa)
AKB17899.12-oxoglutarate oxidoreductase, beta subunit. (283 aa)
AKB17900.12-oxoglutarate oxidoreductase, alpha subunit. (579 aa)
AKB17961.1Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (302 aa)
purDPhosphoribosylamine--glycine ligase; Belongs to the GARS family. (433 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (187 aa)
AKB17971.1Sulfopyruvate decarboxylase - beta subunit. (382 aa)
AKB17972.1Cysteate synthase; Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate. (416 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (553 aa)
AKB18117.1Aspartate aminotransferase. (380 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (143 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (369 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1070 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (395 aa)
AKB18467.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)
AKB18585.1Phosphoserine aminotransferase. (370 aa)
purQPhosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (232 aa)
purSPhosphoribosylformylglycinamidine synthase, PurS subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (83 aa)
AKB18623.1Asparagine synthetase (glutamine-hydrolyzing). (519 aa)
AKB18643.1Coenzyme B synthesis from 2-oxoglutarate: steps 1, 6, and 10; Belongs to the alpha-IPM synthase/homocitrate synthase family. (406 aa)
gapNAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (335 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (268 aa)
trpB-2Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (275 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (376 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (234 aa)
trpEAnthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] (571 aa)
AKB18742.1Anthranilate synthase, amidotransferase component. (200 aa)
AKB18747.1Homoserine dehydrogenase. (332 aa)
guaABGMP synthase (glutamine-hydrolyzing), ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP. (305 aa)
AKB18782.1D-arabino-3-hexulose 6-phosphate formaldehyde lyase; Hypothetical protein with distant similarity to Ribonuclease E inhibitor RraA (former MenG). (383 aa)
pyrBAspartate carbamoyltransferase. (298 aa)
pyrIAspartate carbamoyltransferase regulatory chain (PyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (291 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (292 aa)
AKB18923.1GCN5-related N-acetyltransferase. (151 aa)
AKB18957.13-isopropylmalate dehydrogenase. (342 aa)
AKB18958.12-isopropylmalate synthase. (443 aa)
AKB19093.1Valine--pyruvate aminotransferase. (396 aa)
AKB19128.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa)
AKB19161.1Pyruvate,phosphate dikinase. (883 aa)
AKB19175.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (523 aa)
pyrKDihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (259 aa)
pyrDDihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (301 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (365 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (273 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa)
AKB19311.1Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (307 aa)
AKB19313.1Glucose-6-phosphate isomerase. (246 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (467 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (120 aa)
hisHImidazole glycerol phosphate synthase amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (202 aa)
AKB19514.1Xanthosine/inosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (184 aa)
AKB19517.1Metal-dependent hydrolase. (243 aa)
katGCatalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (732 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (221 aa)
AKB19565.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (248 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (336 aa)
argJGlutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (395 aa)
pfkCADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (491 aa)
AKB19596.1ADP-dependent glucokinase. (511 aa)
AKB19636.1Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. (295 aa)
AKB19651.1Acetolactate synthase; Belongs to the TPP enzyme family. (544 aa)
argHArgininosuccinate lyase. (491 aa)
AKB19692.1Hypothetical protein. (215 aa)
AKB19704.1Fructose-1,6-bisphosphatase, GlpX type; Belongs to the FBPase class 2 family. (362 aa)
AKB19791.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (405 aa)
AKB19793.1Phosphoribosylaminoimidazole carboxylase catalytic subunit. (131 aa)
AKB19794.1Chorismate mutase I. (95 aa)
aroKShikimate kinase II. (293 aa)
AKB19800.16-phospho-3-hexuloisomerase. (204 aa)
AKB19801.1Biosynthetic Aromatic amino acid aminotransferase alpha / Aspartate aminotransferase. (370 aa)
hisEPhosphoribosyl-ATP pyrophosphatase. (104 aa)
leuC-23-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (461 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (229 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa)
AKB19906.1AMP phosphohydrolase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. (506 aa)
AKB19909.1Shikimate kinase I. (169 aa)
AKB19945.1NAD-dependent malic enzyme. (423 aa)
AKB19965.1LL-diaminopimelate aminotransferase, methanococcal. (385 aa)
AKB19997.1Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase beta subunit. (208 aa)
AKB19998.1Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit. (280 aa)
AKB20157.1dCMP deaminase. (159 aa)
apgM2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (403 aa)
AKB20162.1Aspartokinase; Belongs to the aspartokinase family. (472 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase. (323 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa)
hisCAspartate aminotransferase / Histidinol-phosphate aminotransferase. (366 aa)
surE5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (267 aa)
AKB20243.1Pyruvate:ferredoxin oxidoreductase, gamma subunit. (182 aa)
AKB20244.1Pyruvate:ferredoxin oxidoreductase, delta subunit. (86 aa)
AKB20245.1Pyruvate:ferredoxin oxidoreductase, alpha subunit. (403 aa)
AKB20246.1Pyruvate:ferredoxin oxidoreductase, beta subunit. (296 aa)
Your Current Organism:
Methanosarcina sp. WWM596
NCBI taxonomy Id: 1434103
Other names: M. sp. WWM596
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