STRINGSTRING
AKB18806.1 AKB18806.1 AKB16915.1 AKB16915.1 aroE aroE AKB17155.1 AKB17155.1 AKB17282.1 AKB17282.1 AKB17352.1 AKB17352.1 proC proC folD folD ilvC ilvC AKB17737.1 AKB17737.1 AKB17825.1 AKB17825.1 AKB17887.1 AKB17887.1 AKB18185.1 AKB18185.1 AKB18186.1 AKB18186.1 AKB18339.1 AKB18339.1 AKB18342.1 AKB18342.1 AKB18452.1 AKB18452.1 AKB18458.1 AKB18458.1 gap gap AKB18715.1 AKB18715.1 AKB18747.1 AKB18747.1 dapB dapB AKB18814.1 AKB18814.1 AKB18834.1 AKB18834.1 AKB18839.1 AKB18839.1 AKB18855.1 AKB18855.1 AKB18886.1 AKB18886.1 AKB18888.1 AKB18888.1 AKB18903.1 AKB18903.1 AKB18904.1 AKB18904.1 AKB18979.1 AKB18979.1 AKB19175.1 AKB19175.1 hemA hemA AKB19188.1 AKB19188.1 AKB19249.1 AKB19249.1 AKB19266.1 AKB19266.1 AKB19311.1 AKB19311.1 nadX nadX argC argC AKB19700.1 AKB19700.1 AKB19728.1 AKB19728.1 AKB19730.1 AKB19730.1 gmd gmd AKB19833.1 AKB19833.1 AKB19864.1 AKB19864.1 ala ala AKB19945.1 AKB19945.1 AKB20037.1 AKB20037.1 AKB20039.1 AKB20039.1 AKB20217.1 AKB20217.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB18806.1UDP-glucose 4-epimerase. (298 aa)
AKB16915.1Prephenate and/or arogenate dehydrogenase (unknown specificity). (476 aa)
aroEShikimate 5-dehydrogenase I alpha; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (280 aa)
AKB17155.1Aspartate-semialdehyde dehydrogenase. (342 aa)
AKB17282.1Glutathione-regulated potassium-efflux system protein KefC. (662 aa)
AKB17352.1Myo-inositol 2-dehydrogenase. (311 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
folDMethylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (335 aa)
AKB17737.1Ornithine cyclodeaminase. (313 aa)
AKB17825.1Acetyl-CoA synthetase (ADP-forming) alpha chain. (476 aa)
AKB17887.1Glutathione-regulated potassium-efflux system protein KefC. (656 aa)
AKB18185.1Potassium channel protein. (225 aa)
AKB18186.1Potassium channel protein. (334 aa)
AKB18339.1Trk system potassium uptake protein TrkA. (216 aa)
AKB18342.1Inositol-1-phosphate synthase. (369 aa)
AKB18452.1Threonine dehydrogenase and related Zn-dependent dehydrogenase. (353 aa)
AKB18458.13-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa)
gapNAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (335 aa)
AKB18715.1NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (416 aa)
AKB18747.1Homoserine dehydrogenase. (332 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (263 aa)
AKB18814.1dTDP-glucose 4,6-dehydratase. (336 aa)
AKB18834.1Gluconate 5-dehydrogenase. (263 aa)
AKB18839.1UDP-N-acetylglucosamine 4,6-dehydratase. (326 aa)
AKB18855.1dTDP-glucose 4,6-dehydratase. (352 aa)
AKB18886.1UDP-glucose 6-dehydrogenase. (427 aa)
AKB18888.1UDP-glucose 4-epimerase. (316 aa)
AKB18903.1Myo-inositol 2-dehydrogenase. (312 aa)
AKB18904.1UDP-glucose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (475 aa)
AKB18979.18-hydroxy-5-deazaflavin:NADPH oxidoreductase. (235 aa)
AKB19175.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (523 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (440 aa)
AKB19188.1Siroheme synthase; Precorrin-2 oxidase; Sirohydrochlorin ferrochelatase. (220 aa)
AKB19249.1Glutathione-regulated potassium-efflux system protein KefC. (672 aa)
AKB19266.1Bifunctional protein: zinc-containing alcohol dehydrogenase; Quinone oxidoreductase (NADPH:quinone reductase); Similar to arginate lyase. (312 aa)
AKB19311.1Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (307 aa)
nadXL-Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (217 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (336 aa)
AKB19700.1Adenosylhomocysteinase; Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine. Likely functions in a S-adenosyl-L- methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions. Can also catalyze the reverse reaction in vitro, i.e. the synthesis of SIH from Hcy and inosine; Belongs to the adenosylhomocysteinase family. (411 aa)
AKB19728.1Kef-type K+ transport systems (NAD-binding component fused to domain related to exopolyphosphatase). (488 aa)
AKB19730.1GDP-mannose 4,6-dehydratase. (283 aa)
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (340 aa)
AKB19833.1Trk system potassium uptake protein TrkA. (612 aa)
AKB19864.1Hypothetical protein. (145 aa)
alaOrnithine cyclodeaminase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily. (312 aa)
AKB19945.1NAD-dependent malic enzyme. (423 aa)
AKB20037.1Trk system potassium uptake protein TrkA. (448 aa)
AKB20039.1Trk system potassium uptake protein TrkA. (448 aa)
AKB20217.1Inositol-1-phosphate synthase. (366 aa)
Your Current Organism:
Methanosarcina sp. WWM596
NCBI taxonomy Id: 1434103
Other names: M. sp. WWM596
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