STRINGSTRING
AKB80673.1 AKB80673.1 AKB80839.1 AKB80839.1 AKB81027.1 AKB81027.1 AKB81425.1 AKB81425.1 AKB82354.1 AKB82354.1 AKB82657.1 AKB82657.1 AKB83134.1 AKB83134.1 AKB83141.1 AKB83141.1 hypA hypA AKB83146.1 AKB83146.1 AKB83232.1 AKB83232.1 cdhC cdhC cdhA cdhA AKB83350.1 AKB83350.1 cbiX cbiX AKB83531.1 AKB83531.1 cdhA-2 cdhA-2 AKB83548.1 AKB83548.1 AKB83549.1 AKB83549.1 AKB83551.1 AKB83551.1 AKB83609.1 AKB83609.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKB80673.1Carbon monoxide dehydrogenase CooS subunit. (627 aa)
AKB80839.1Nickel responsive regulator NikR; Transcriptional regulator. (133 aa)
AKB81027.1Nickel responsive regulator NikR; Transcriptional regulator. (141 aa)
AKB81425.1Ni2+-binding GTPase involved in regulation of expression and maturation of hydrogenase. (234 aa)
AKB82354.1Ni2+-binding GTPase involved in regulation of expression and maturation of hydrogenase. (231 aa)
AKB82657.1Hypothetical protein; Belongs to the LarC family. (396 aa)
AKB83134.1Methanophenazine hydrogenase large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (596 aa)
AKB83141.1Methanophenazine hydrogenase large subunit. (591 aa)
hypA[NiFe] hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (133 aa)
AKB83146.1[NiFe] hydrogenase nickel incorporation-associated protein HypB. (220 aa)
AKB83232.1Energy-conserving hydrogenase (ferredoxin), subunit E. (358 aa)
cdhCCO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (472 aa)
cdhACO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (808 aa)
AKB83350.1Coenzyme F420 hydrogenase subunit beta. (346 aa)
cbiXSirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin. (178 aa)
AKB83531.1CO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase. (472 aa)
cdhA-2CO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (807 aa)
AKB83548.1Hypothetical protein. (291 aa)
AKB83549.1Coenzyme F420 hydrogenase subunit gamma. (293 aa)
AKB83551.1Coenzyme F420 hydrogenase subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (456 aa)
AKB83609.1Nickel responsive regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (140 aa)
Your Current Organism:
Methanosarcina barkeri 3
NCBI taxonomy Id: 1434107
Other names: M. barkeri 3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.