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hisA hisA hisF hisF aroB aroB pyrF pyrF pdxS pdxS AKB81789.1 AKB81789.1 trpF-2 trpF-2 trpA trpA trpC trpC fae-hps fae-hps AKB83887.1 AKB83887.1 AKB83950.1 AKB83950.1 trpF trpF
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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hisAPhosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (245 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (273 aa)
aroB3,7-dideoxy-D-threo-hepto-2, 6-diulosonate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (380 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (221 aa)
pdxSPyridoxine biosynthesis glutamine amidotransferase, synthase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (298 aa)
AKB81789.1Orotidine 5'-phosphate decarboxylase. (298 aa)
trpF-2Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (238 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (267 aa)
fae-hpsFormaldehyde activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (392 aa)
AKB83887.1Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase related protein; Belongs to the HisA/HisF family. (237 aa)
AKB83950.1D-arabino-3-hexulose 6-phosphate formaldehyde lyase; Hypothetical protein with distant similarity to Ribonuclease E inhibitor RraA (former MenG). (413 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (226 aa)
Your Current Organism:
Methanosarcina barkeri 3
NCBI taxonomy Id: 1434107
Other names: M. barkeri 3
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