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| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | AKB76485.1 | Dephospho-CoA kinase archaeal, predicted; Belongs to the UPF0200 family. (199 aa) |
| | AKB76491.1 | 5'-nucleotidase. (552 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (222 aa) |
| | guaAA | GMP synthase (glutamine-hydrolyzing), amidotransferase subunit; Catalyzes the synthesis of GMP from XMP. (189 aa) |
| | AKB76539.1 | Xanthine-guanine phosphoribosyltransferase. (224 aa) |
| | rbcL | Ribulose-1,5-bisphosphate carboxylase, Type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (428 aa) |
| | thyA | Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily. (217 aa) |
| | mptA | GTP cyclohydrolase I type 2; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (318 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa) |
| | guaAB | GMP synthase (glutamine-hydrolyzing), ATP pyrophosphatase subunit; Catalyzes the synthesis of GMP from XMP. (305 aa) |
| | pyrB | Aspartate carbamoyltransferase. (327 aa) |
| | pyrI | Aspartate carbamoyltransferase regulatory chain (PyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. (156 aa) |
| | tmk | Thymidylate kinase. (205 aa) |
| | AKB76734.1 | Geranylgeranyl/isoprenyl reductase. (385 aa) |
| | AKB76746.1 | Sensory transduction histidine kinase. (816 aa) |
| | AKB76753.1 | 7,8 dihydropteroate synthase (methanopterin). (222 aa) |
| | AKB76802.1 | Hypothetical protein. (508 aa) |
| | AKB76825.1 | Molybdopterin biosynthesis protein MoeA; Periplasmic molybdate-binding domain. (648 aa) |
| | thiC | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (428 aa) |
| | AKB76931.1 | Sensory transduction histidine kinase. (409 aa) |
| | AKB76937.1 | (S)-3-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (247 aa) |
| | AKB76939.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (448 aa) |
| | AKB76942.1 | Flagella-related protein FlaI. (839 aa) |
| | AKB76961.1 | GDP-mannose mannosyl hydrolase. (145 aa) |
| | AKB76977.1 | Beta-ribofuranosylaminobenzene 5'-phosphate synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (297 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (515 aa) |
| | AKB76984.1 | IMP cyclohydrolase; Phosphoribosylaminoimidazolecarboxamide formyltransferase. (538 aa) |
| | AKB76989.1 | Sensory transduction histidine kinase. (720 aa) |
| | AKB77005.1 | Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family. (364 aa) |
| | AKB77008.1 | Adenylate cyclase. (176 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase, synthetase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...] (715 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (237 aa) |
| | AKB77044.1 | Aldehyde dehydrogenase. (474 aa) |
| | AKB77051.1 | Molybdopterin converting factor small subunit. (97 aa) |
| | AKB77052.1 | Molybdopterin biosynthesis MoeA protein. (397 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (385 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (425 aa) |
| | atpE | V-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (183 aa) |
| | atpC | V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (360 aa) |
| | atpF | V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (101 aa) |
| | atpA | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (555 aa) |
| | atpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (460 aa) |
| | atpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (209 aa) |
| | AKB77104.1 | Sensory transduction histidine kinase. (669 aa) |
| | AKB77107.1 | Sensory transduction histidine kinase. (612 aa) |
| | AKB77122.1 | Sensory transduction histidine kinase. (467 aa) |
| | AKB77123.1 | Anti-sigma B factor RsbT; Phosphoserine phosphatase RsbX. (189 aa) |
| | AKB77124.1 | Anti-sigma B factor RsbT. (96 aa) |
| | AKB77128.1 | Thiamine monophosphate kinase. (326 aa) |
| | AKB77189.1 | Geranylgeranyl diphosphate reductase. (396 aa) |
| | AKB77193.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa) |
| | cdhE | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (469 aa) |
| | cdhC | CO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (469 aa) |
| | cdhA | CO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (805 aa) |
| | AKB77240.1 | D-glycerate 2-kinase. (431 aa) |
| | AKB77245.1 | Glutamate synthase [NADPH] small chain. (469 aa) |
| | AKB77246.1 | Putative electron-transfer protein. (281 aa) |
| | AKB77275.1 | Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase. (214 aa) |
| | AKB77284.1 | Nicotinamide-nucleotide adenylyltransferase, NadM family. (173 aa) |
| | AKB77285.1 | AMP/CMP kinase AK6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (186 aa) |
| | uppS | Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (313 aa) |
| | AKB77296.1 | NAD synthetase. (355 aa) |
| | AKB77304.1 | Xanthosine/inosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (184 aa) |
| | AKB77305.1 | YgjD/Kae1/Qri7 family, required for N6-threonylcarbamoyl adenosine t(6)A37 modification in tRNA; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belo [...] (562 aa) |
| | AKB77309.1 | Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (181 aa) |
| | AKB77314.1 | 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase. (387 aa) |
| | egsA | Glycerol-1-phosphate dehydrogenase [NAD(P)]; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. (354 aa) |
| | AKB77348.1 | Pyruvate-utilizing enzyme, similar to phosphoenolpyruvate synthase. (212 aa) |
| | AKB77349.1 | Pyruvate-utilizing enzyme, similar to phosphoenolpyruvate synthase. (511 aa) |
| | AKB77356.1 | Hypothetical protein. (179 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (409 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa) |
| | pfkC | ADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (491 aa) |
| | AKB77481.1 | Sensory transduction histidine kinase. (851 aa) |
| | AKB77520.1 | Sensory transduction histidine kinase. (1073 aa) |
| | AKB77524.1 | Sensory transduction histidine kinase. (1944 aa) |
| | AKB77532.1 | Phosphopantothenate synthetase, archaeal. (240 aa) |
| | AKB77533.1 | Pantoate kinase, archaeal. (300 aa) |
| | AKB77534.1 | Phosphopantothenoylcysteine synthetase. (437 aa) |
| | AKB77546.1 | Sensory transduction histidine kinase. (1079 aa) |
| | AKB77586.1 | Phytol kinase. (198 aa) |
| | AKB77611.1 | Response regulator receiver. (141 aa) |
| | AKB77617.1 | Flagella-related protein FlaI. (611 aa) |
| | AKB77626.1 | Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (418 aa) |
| | AKB77634.1 | Signal transduction histidine kinase CheA. (969 aa) |
| | AKB77646.1 | Flagella-related protein FlaI. (617 aa) |
| | AKB77652.1 | Haloacid dehalogenase-like hydrolase. (217 aa) |
| | AKB77660.1 | Haloacid dehalogenase-like hydrolase. (254 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (618 aa) |
| | AKB77693.1 | Phosphoglycerate mutase family protein. (209 aa) |
| | AKB77733.1 | Sensory transduction histidine kinase. (588 aa) |
| | ribL | FMN adenylyltransferase, type 3 archaeal; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (139 aa) |
| | AKB77761.1 | Hypothetical protein. (1015 aa) |
| | AKB77764.1 | Phytol kinase. (223 aa) |
| | thi4 | Thiazole biosynthetic enzyme Thi4; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (260 aa) |
| | thiC-2 | Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (428 aa) |
| | AKB77822.1 | Sensory transduction histidine kinase. (201 aa) |
| | AKB77847.1 | Sensory transduction histidine kinase. (930 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (433 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (187 aa) |
| | carS | Phosphatidate cytidylyltransferase; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (175 aa) |
| | AKB77887.1 | Sensory transduction histidine kinase. (730 aa) |
| | AKB77900.1 | Tungsten-containing formylmethanofuran dehydrogenase 2 subunit G. (154 aa) |
| | AKB77911.1 | Sensory transduction histidine kinase. (250 aa) |
| | AKB77992.1 | Geranylgeranyl reductase. (354 aa) |
| | AKB77995.1 | Sensory transduction histidine kinase. (170 aa) |
| | AKB78005.1 | Sensory transduction histidine kinase. (364 aa) |
| | AKB78006.1 | Sensory transduction histidine kinase. (120 aa) |
| | AKB78010.1 | Inositol-1-phosphate synthase. (368 aa) |
| | AKB78022.1 | Hypothetical protein. (290 aa) |
| | AKB78027.1 | Sensory transduction histidine kinase. (835 aa) |
| | AKB78033.1 | Response regulator receiver. (127 aa) |
| | AKB78034.1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (492 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1092 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (369 aa) |
| | AKB78064.1 | Ketoisovalerate oxidoreductase subunit VorC. (82 aa) |
| | AKB78065.1 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (557 aa) |
| | AKB78073.1 | Asparagine synthetase (glutamine-hydrolyzing). (504 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (224 aa) |
| | AKB78089.1 | Molybdopterin-guanine dinucleotide biosynthesis protein MobB. (278 aa) |
| | nadK | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (275 aa) |
| | AKB78103.1 | Inositol-1-monophosphatase. (267 aa) |
| | gap | NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (335 aa) |
| | AKB78108.1 | Hypothetical protein. (456 aa) |
| | AKB78177.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa) |
| | AKB78180.1 | Digeranylgeranylglycerophospholipid reductase. (421 aa) |
| | AKB78225.1 | Sensory transduction histidine kinase. (584 aa) |
| | AKB78284.1 | Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s). (1056 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (83 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ a [...] (232 aa) |
| | AKB78420.1 | Glutamate decarboxylase. (468 aa) |
| | AKB78422.1 | 7,8 dihydropteroate synthase (methanopterin). (326 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (310 aa) |
| | thiE | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (238 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (261 aa) |
| | fdhD | Formate dehydrogenase chain D; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (245 aa) |
| | AKB78497.1 | Hypothetical protein. (92 aa) |
| | AKB78500.1 | Phosphomethylpyrimidine kinase; Thiamin-phosphate synthase ThiN. (194 aa) |
| | AKB78534.1 | Phosphoesterase. (396 aa) |
| | rpiA | Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (234 aa) |
| | AKB78556.1 | Xanthine-guanine phosphoribosyltransferase. (164 aa) |
| | AKB78565.1 | Sensory transduction histidine kinase. (94 aa) |
| | AKB78569.1 | Sensory transduction histidine kinase. (425 aa) |
| | AKB78570.1 | Shikimate kinase I. (169 aa) |
| | AKB78574.1 | AMP phosphohydrolase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. (506 aa) |
| | AKB78594.1 | Response regulator receiver. (284 aa) |
| | AKB78599.1 | Sodium-transporting ATPase subunit D. (477 aa) |
| | AKB78606.1 | Sodium-transporting ATPase subunit A. (589 aa) |
| | mptE | 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP). (214 aa) |
| | AKB78659.1 | Hypothetical protein. (633 aa) |
| | AKB78671.1 | Fructokinase. (309 aa) |
| | AKB78688.1 | Hypothetical protein. (385 aa) |
| | AKB78707.1 | Orotate phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (203 aa) |
| | AKB78710.1 | Sensory transduction histidine kinase. (890 aa) |
| | AKB78715.1 | Hypothetical protein. (503 aa) |
| | AKB78758.1 | Metallo-beta-lactamase family protein. (456 aa) |
| | AKB78767.1 | Sensory transduction histidine kinase. (237 aa) |
| | AKB78768.1 | Sensory transduction histidine kinase. (171 aa) |
| | AKB78790.1 | Sensory transduction histidine kinase. (1006 aa) |
| | purP | Phosphoribosylaminoimidazolecarboxamide formyltransferase(alternate form); Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (356 aa) |
| | AKB78815.1 | Sensory transduction histidine kinase. (678 aa) |
| | AKB78823.1 | Sensory transduction histidine kinase. (587 aa) |
| | AKB78829.1 | Pyruvate:ferredoxin oxidoreductase, beta subunit. (296 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (238 aa) |
| | AKB78839.1 | Sensory transduction histidine kinase. (413 aa) |
| | AKB78847.1 | Hypothetical protein. (186 aa) |
| | AKB78872.1 | Hypothetical protein. (346 aa) |
| | AKB78874.1 | Hypothetical protein. (69 aa) |
| | AKB78882.1 | Transcriptional regulator, TrmB family. (254 aa) |
| | AKB78914.1 | Phosphoenolpyruvate synthase. (922 aa) |
| | AKB78935.1 | Fructokinase. (320 aa) |
| | AKB78945.1 | Hypothetical protein. (1170 aa) |
| | AKB78971.1 | Hypothetical protein. (602 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa) |
| | gpmI-2 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (517 aa) |
| | AKB79004.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (804 aa) |
| | gap-2 | NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (335 aa) |
| | pgk-2 | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (412 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (401 aa) |
| | AKB79031.1 | Serine/threonine protein kinase. (375 aa) |
| | AKB79032.1 | Hypothetical protein. (998 aa) |
| | AKB79060.1 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase. (251 aa) |
| | AKB79064.1 | Indolepyruvate oxidoreductase subunit IorB. (225 aa) |
| | AKB79074.1 | Molybdenum cofactor biosynthesis protein MoaD. (100 aa) |
| | AKB79076.1 | Sensory transduction histidine kinase. (885 aa) |
| | AKB79215.1 | MutT protein. (173 aa) |
| | AKB79230.1 | Sensory transduction histidine kinase. (672 aa) |
| | AKB79252.1 | NADH pyrophosphatase. (286 aa) |
| | AKB79271.1 | Sensory transduction histidine kinase. (622 aa) |
| | AKB79274.1 | Putative NTPase; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. (175 aa) |
| | thiI | tRNA S(4)U 4-thiouridine synthase (former ThiI); Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (438 aa) |
| | AKB79279.1 | Sensory transduction histidine kinase. (1141 aa) |
| | AKB79280.1 | Sensory transduction histidine kinase. (1373 aa) |
| | AKB79283.1 | Delta 1-pyrroline-5-carboxylate synthetase. (225 aa) |
| | AKB79284.1 | Putative H4MPT-linked C1 transfer pathway protein. (353 aa) |
| | AKB79294.1 | Digeranylgeranylglycerophospholipid reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. (407 aa) |
| | cofC | Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (246 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (143 aa) |
| | pdxT | Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (199 aa) |
| | pdxS | Pyridoxine biosynthesis glutamine amidotransferase, synthase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (298 aa) |
| | aroK | Shikimate kinase II. (293 aa) |
| | AKB79444.1 | Phosphoribosylaminoimidazole carboxylase catalytic subunit. (131 aa) |
| | AKB79446.1 | Cytidine kinase; Belongs to the carbohydrate kinase PfkB family. (299 aa) |
| | AKB79453.1 | Phosphate regulon transcriptional regulatory protein PhoB (SphR). (170 aa) |
| | AKB79455.1 | Hydrolase, HAD superfamily. (261 aa) |
| | AKB79464.1 | Succinate-semialdehyde dehydrogenase [NADP+]. (454 aa) |
| | AKB79502.1 | ABC1 family protein. (544 aa) |
| | AKB79511.1 | ABC1 family protein. (551 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (485 aa) |
| | AKB79532.1 | Phosphomethylpyrimidine kinase; Thiamin-phosphate synthase ThiN. (448 aa) |
| | AKB79543.1 | Coenzyme F420:L-glutamate ligase. (259 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (287 aa) |
| | AKB79549.1 | Phosphoribosylglycinamide formyltransferase. (202 aa) |
| | nadE | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (256 aa) |
| | AKB79561.1 | Hypothetical protein. (175 aa) |
| | AKB79567.1 | Phosphoglycolate phosphatase, archaeal type; Catalyzes the dephosphorylation of 2-phosphoglycolate. (226 aa) |
| | coaD | Phosphopantetheine adenylyltransferase, type II eukaryotic; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (154 aa) |
| | nnrD | NAD(P)HX epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epime [...] (500 aa) |
| | moaC | Molybdenum cofactor biosynthesis enzyme; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (155 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (283 aa) |
| | AKB79631.1 | Two component system histidine kinase. (843 aa) |
| | cmk | Cytidylate kinase. (180 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | AKB79733.1 | Indolepyruvate oxidoreductase subunit IorB. (200 aa) |
| | AKB79736.1 | Sensory transduction histidine kinase. (971 aa) |
| | cdhA-2 | CO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (805 aa) |
| | cdhC-2 | CO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (467 aa) |
| | cdhE-2 | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (469 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (220 aa) |
| | AKB79757.1 | (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (289 aa) |
| | nadA-2 | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (304 aa) |
| | AKB79760.1 | L-Aspartate dehydrogenase. (217 aa) |
| | AKB79761.1 | Quinolinate phosphoribosyltransferase (decarboxylating); Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (277 aa) |
| | AKB79799.1 | Orotate phosphoribosyltransferase related protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (204 aa) |
| | AKB79818.1 | Serine/threonine-protein kinase RIO1. (262 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (467 aa) |
| | AKB79843.1 | Sensory transduction histidine kinase. (215 aa) |
| | AKB79844.1 | Sensory transduction histidine kinase. (709 aa) |
| | AKB79877.1 | Glucose-6-phosphate isomerase. (246 aa) |
| | AKB79886.1 | Purine nucleoside phosphoramidase. (139 aa) |
| | AKB79909.1 | Digeranylgeranylglyceryl phosphate synthase. (297 aa) |
| | AKB79920.1 | Signal-transducing histidine kinase. (570 aa) |
| | AKB79941.1 | Sensory transduction histidine kinase. (387 aa) |
| | AKB79943.1 | Sensory transduction histidine kinase. (1026 aa) |
| | AKB79949.1 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (197 aa) |
| | AKB79954.1 | Hypothetical protein. (151 aa) |
| | hpt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily. (190 aa) |
| | cofD | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (309 aa) |
| | AKB79996.1 | Putative dNTP triphosphohydrolase, Archaeal subgroup. (405 aa) |
| | AKB80010.1 | Indolepyruvate oxidoreductase subunit IorA. (239 aa) |
| | AKB80012.1 | Triphosphoribosyl-dephospho-CoA synthetase. (351 aa) |
| | AKB80014.1 | Geranylgeranyl diphosphate reductase. (389 aa) |
| | AKB80015.1 | Geranylgeranyl diphosphate reductase. (374 aa) |
| | AKB80016.1 | Hypothetical protein. (332 aa) |
| | AKB80085.1 | Sensory transduction histidine kinase. (635 aa) |
| | AKB80086.1 | Sensory transduction histidine kinase. (672 aa) |
| | AKB80104.1 | Pyruvate,phosphate dikinase. (883 aa) |
| | AKB80108.1 | Isopentenyl phosphate kinase; Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. (262 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (301 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (259 aa) |
| | pyrD | Dihydroorotate dehydrogenase, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (314 aa) |
| | ribK | DNA-binding HTH domain in riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (224 aa) |
| | AKB80159.1 | Hypothetical protein. (95 aa) |
| | AKB80163.1 | Deoxynucleoside 5'-monophosphate N-glycosidase; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base; Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family. (149 aa) |
| | AKB80175.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (170 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (171 aa) |
| | AKB80252.1 | Circadian phase modifier. (267 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (233 aa) |
| | AKB80280.1 | Beta-ribofuranosylaminobenzene 5'-phosphate synthase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (323 aa) |
| | AKB80297.1 | Molybdenum transport system protein ModD; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (263 aa) |
| | AKB80345.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (203 aa) |
| | AKB80349.1 | Thiamin biosynthesis protein ThiC. (415 aa) |
| | AKB80350.1 | Sensory transduction histidine kinase. (828 aa) |
| | AKB80372.1 | Type II secretion system protein. (558 aa) |
| | fdhD-2 | Formate dehydrogenase chain D; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. (247 aa) |
| | purP-2 | Phosphoribosylaminoimidazolecarboxamide formyltransferase(alternate form); Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. (356 aa) |
| | AKB80415.1 | Molybdenum cofactor biosynthesis protein MoaB. (179 aa) |
| | ppa | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (169 aa) |
| | AKB80468.1 | dCMP deaminase. (150 aa) |
| | cofE | Coenzyme F420:L-glutamate ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. (254 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (403 aa) |
| | AKB80475.1 | Aspartokinase; Belongs to the aspartokinase family. (472 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (346 aa) |
| | mptD | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD). (118 aa) |
| | AKB80491.1 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (247 aa) |
| | asd | Phosphatidylserine decarboxylase; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily. (208 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (349 aa) |
| | surE | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (263 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family. (732 aa) |
| | AKB80525.1 | Inositol-1-phosphate synthase. (366 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (339 aa) |
| | AKB80551.1 | Pyruvate:ferredoxin oxidoreductase, gamma subunit. (182 aa) |
| | AKB80552.1 | Pyruvate:ferredoxin oxidoreductase, delta subunit. (110 aa) |
| | AKB80553.1 | Pyruvate:ferredoxin oxidoreductase, alpha subunit. (402 aa) |
| | AKB80554.1 | Pyruvate:ferredoxin oxidoreductase, beta subunit. (296 aa) |
| | AKB80569.1 | Signal transduction histidine kinase CheA. (677 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (399 aa) |
