Your Input: | |
| | fae-hps | Formaldehyde activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the N-terminal section; belongs to the formaldehyde- activating enzyme family. (392 aa) |
| | aroA | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (265 aa) |
| | mtrE | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (304 aa) |
| | mtrD | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (249 aa) |
| | mtrC | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (266 aa) |
| | mtrB | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (108 aa) |
| | mtrA | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family. (240 aa) |
| | mtrF | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit F; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (72 aa) |
| | mtrG | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. (73 aa) |
| | mtrH | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit H; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA. (316 aa) |
| | AKB73396.1 | Coenzyme F420 hydrogenase subunit beta. (387 aa) |
| | AKB73417.1 | Methyl coenzyme M reductase alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (571 aa) |
| | AKB73418.1 | Methyl coenzyme M reductase gamma subunit. (248 aa) |
| | AKB73419.1 | Methyl coenzyme M reductase operon protein C. (206 aa) |
| | AKB73420.1 | Methyl coenzyme M reductase operon protein D. (170 aa) |
| | AKB73421.1 | Methyl coenzyme M reductase beta subunit. (434 aa) |
| | aroA-3 | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (258 aa) |
| | AKB73455.1 | FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (170 aa) |
| | AKB73499.1 | Methanol methyltransferase corrinoid protein. (258 aa) |
| | AKB73500.1 | Methanol:corrinoid methyltransferase. (461 aa) |
| | AKB73522.1 | FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (200 aa) |
| | AKB73523.1 | Polyferredoxin protein MvhB. (340 aa) |
| | AKB73524.1 | Formylmethanofuran dehydrogenase subunit A. (584 aa) |
| | AKB73525.1 | Formylmethanofuran dehydrogenase (molybdenum) subunit C. (269 aa) |
| | AKB73526.1 | Formylmethanofuran dehydrogenase (molybdenum) subunit D. (129 aa) |
| | AKB73527.1 | Formylmethanofuran dehydrogenase (molybdenum) subunit B. (433 aa) |
| | AKB73547.1 | Dimethylamine methyltransferase corrinoid protein. (164 aa) |
| | AKB73548.1 | Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family. (495 aa) |
| | AKB73549.1 | Trimethylamine methyltransferase corrinoid protein. (216 aa) |
| | AKB73553.1 | Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (467 aa) |
| | AKB73589.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (523 aa) |
| | AKB73620.1 | Valine--pyruvate aminotransferase. (396 aa) |
| | AKB73630.1 | Methylcobamide:CoM methyltransferase MtaA. (341 aa) |
| | cofD | 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (330 aa) |
| | AKB73685.1 | CoB--CoM heterodisulfide reductase 2 iron-sulfur subunit D. (419 aa) |
| | AKB73686.1 | CoB--CoM heterodisulfide reductase 2 subunit E. (242 aa) |
| | AKB73703.1 | Ferredoxin. (87 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (515 aa) |
| | AKB73811.1 | Methyl coenzyme M reductase system component A2. (537 aa) |
| | AKB73840.1 | Putative ABC transporter ATP-binding protein. (578 aa) |
| | AKB73886.1 | Fructose-bisphosphate aldolase/6-deoxy-5-ketofructose 1-phosphate synthase. (307 aa) |
| | cdhE | 5-tetrahydromethanopterin:corrinoid iron-sulfur protein methyltransferase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. (469 aa) |
| | cdhD | CO dehydrogenase/acetyl-CoA synthase subunit delta, corrinoid iron-sulfur subcomplex small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. Probably maintains the overall quaternary structure of the ACDS complex. (437 aa) |
| | cdhC | CO dehydrogenase/acetyl-CoA synthase subunit beta, acetyl-CoA synthase; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron- sulfur protein (the gamma-delta complex). (469 aa) |
| | cdhB | CO dehydrogenase/acetyl-CoA synthase subunit epsilon, CO dehydrogenase subcomplex; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD- mediated CO oxidation. (170 aa) |
| | cdhA | CO dehydrogenase/acetyl-CoA synthase subunit alpha, CO dehydrogenase subcomplex; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. (806 aa) |
| | AKB73953.1 | FmdE, Molybdenum formylmethanofuran dehydrogenase operon. (203 aa) |
| | AKB73960.1 | Fructose-1,6-bisphosphatase, GlpX type; Belongs to the FBPase class 2 family. (362 aa) |
| | glyA | Serine hydroxymethyltransferase / L-threonine aldolase / L-allo-threonine aldolase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa) |
| | AKB74171.1 | Delta 1-pyrroline-5-carboxylate synthetase. (225 aa) |
| | AKB74172.1 | Putative H4MPT-linked C1 transfer pathway protein. (329 aa) |
| | AKB74173.1 | COG1821 family protein. (325 aa) |
| | AKB74207.1 | Coenzyme gamma-F420-2:alpha-L-glutamate ligase. (309 aa) |
| | AKB74228.1 | 6-phospho-3-hexuloisomerase. (204 aa) |
| | AKB74257.1 | acetyl-CoA decarbonylase/synthase complex subunit alpha. (659 aa) |
| | AKB74281.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa) |
| | AKB74289.1 | N5-methyltetrahydromethanopterin:coenzyme M methyltransferase subunit A. (182 aa) |
| | mch | N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (321 aa) |
| | AKB74341.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa) |
| | AKB74439.1 | Formaldehyde activating enzyme. (168 aa) |
| | AKB74489.1 | Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (344 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | AKB74640.1 | Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (339 aa) |
| | AKB74641.1 | Methanol:corrinoid methyltransferase. (461 aa) |
| | AKB74642.1 | Methanol methyltransferase corrinoid protein. (255 aa) |
| | gpmA | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | cofC | 2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (208 aa) |
| | cofH | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (387 aa) |
| | cofH-2 | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. (376 aa) |
| | cofG | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil; Belongs to the radical SAM superfamily. CofG family. (290 aa) |
| | AKB74725.1 | CO dehydrogenase iron-sulfur protein CooF. (169 aa) |
| | AKB74726.1 | Carbon monoxide dehydrogenase CooS subunit. (624 aa) |
| | AKB74814.1 | Coenzyme B synthesis from 2-oxoglutarate: steps 1, 6, and 10; Belongs to the alpha-IPM synthase/homocitrate synthase family. (393 aa) |
| | AKB74838.1 | Polyferredoxin protein MvhB. (511 aa) |
| | AKB74839.1 | CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (793 aa) |
| | AKB74841.1 | Acetyl-CoA decarbonylase/synthase complex subunit gamma 1. (154 aa) |
| | AKB74842.1 | Formylmethanofuran dehydrogenase subunit B. (414 aa) |
| | AKB74843.1 | Formylmethanofuran dehydrogenase subunit D. (132 aa) |
| | AKB74928.1 | Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (467 aa) |
| | AKB74929.1 | Dimethylamine methyltransferase corrinoid protein. (214 aa) |
| | AKB75198.1 | Phosphoserine aminotransferase. (370 aa) |
| | AKB75268.1 | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (556 aa) |
| | AKB75295.1 | Tetrahydromethanopterin S-methyltransferase subunit H. (310 aa) |
| | leuC-2 | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (413 aa) |
| | AKB75389.1 | Sulfopyruvate decarboxylase - beta subunit. (384 aa) |
| | AKB75463.1 | CoB--CoM heterodisulfide reductase subunit B. (296 aa) |
| | AKB75464.1 | CoB--CoM heterodisulfide reductase subunit C. (236 aa) |
| | AKB75465.1 | CoB--CoM heterodisulfide reductase subunit A; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). (813 aa) |
| | AKB75478.1 | Coenzyme B synthesis from 2-oxoglutarate: steps 5, 9, and 13. (331 aa) |
| | mer | 5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family. (328 aa) |
| | AKB75583.1 | Methylcobamide:CoM methyltransferase MtaA. (346 aa) |
| | AKB75586.1 | Phosphate acetyltransferase. (333 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (408 aa) |
| | pfkC | ADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (491 aa) |
| | AKB75614.1 | ADP-dependent glucokinase. (501 aa) |
| | hacB | Coenzyme B synthesis from 2-oxoglutarate: steps 4, 7, 8, 11, and 12 (small subunit); Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis path [...] (165 aa) |
| | AKB75737.1 | Trimethylamine methyltransferase corrinoid protein. (217 aa) |
| | AKB75738.1 | Trimethylamine:corrinoid methyltransferase; Pyrrolysine-containing; Belongs to the trimethylamine methyltransferase family. (495 aa) |
| | AKB75739.1 | Dimethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (468 aa) |
| | AKB75740.1 | Dimethylamine methyltransferase corrinoid protein. (216 aa) |
| | AKB75872.1 | Methylcobamide:CoM methyltransferase MtaA. (345 aa) |
| | AKB75884.1 | Formylmethanofuran dehydrogenase (tungsten) subunit D. (127 aa) |
| | AKB75885.1 | Formylmethanofuran dehydrogenase subunit B. (434 aa) |
| | AKB75886.1 | Formylmethanofuran dehydrogenase subunit A. (572 aa) |
| | AKB75887.1 | Formylmethanofuran dehydrogenase subunit C. (252 aa) |
| | AKB75899.1 | Malate dehydrogenase; Belongs to the LDH/MDH superfamily. (307 aa) |
| | AKB75982.1 | Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (344 aa) |
| | AKB75983.1 | Dimethylsulfide:corrinoid methyltransferase. (264 aa) |
| | AKB76028.1 | Coenzyme F420 hydrogenase subunit beta. (344 aa) |
| | AKB76045.1 | CoB--CoM heterodisulfide reductase subunit C. (161 aa) |
| | AKB76046.1 | CoB--CoM heterodisulfide reductase subunit B. (300 aa) |
| | mfnB | Duf556 family protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P). (236 aa) |
| | mtd | F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT. (276 aa) |
| | AKB76186.1 | Phosphoserine phosphatase. (235 aa) |
| | AKB76216.1 | Methanol:corrinoid methyltransferase. (461 aa) |
| | AKB76217.1 | Methanol methyltransferase corrinoid protein. (258 aa) |
| | AKB76226.1 | Methylcobalamin:coenzyme M methyltransferase, methanol-specific. (342 aa) |
| | AKB76243.1 | Methylcobamide:CoM methyltransferase MtaA. (370 aa) |
| | AKB76275.1 | Coenzyme F420-reducing hydrogenase subunit beta. (464 aa) |
| | AKB76314.1 | D-arabino-3-hexulose 6-phosphate formaldehyde lyase; Hypothetical protein with distant similarity to Ribonuclease E inhibitor RraA (former MenG). (426 aa) |
| | ftr | Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family. (297 aa) |
| | AKB76372.1 | Pyruvate:ferredoxin oxidoreductase, beta subunit. (296 aa) |
| | AKB76373.1 | Pyruvate:ferredoxin oxidoreductase, alpha subunit. (403 aa) |
| | AKB76374.1 | Pyruvate:ferredoxin oxidoreductase, delta subunit. (86 aa) |
| | AKB76375.1 | Pyruvate:ferredoxin oxidoreductase, gamma subunit. (182 aa) |
| | apgM | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (397 aa) |
| | cofE | Coenzyme F420:L-glutamate ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. (254 aa) |
| | AKB76463.1 | Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (458 aa) |
| | AKB76464.1 | Monomethylamine methyltransferase corrinoid protein. (217 aa) |
| | AKB76465.1 | Monomethylamine:corrinoid methyltransferase; Pyrrolysine-containing. (458 aa) |
| | AKB76466.1 | Monomethylamine methyltransferase corrinoid protein. (217 aa) |
| | AKB76467.1 | Methylcobalamin:coenzyme M methyltransferase, methylamine-specific. (318 aa) |
| | mfnA | L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (395 aa) |
